دورية أكاديمية
Toward the use of proxy reports for estimating long-term patient-reported outcomes in multiple sclerosis.
| العنوان: | Toward the use of proxy reports for estimating long-term patient-reported outcomes in multiple sclerosis. |
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| المؤلفون: | Sonder JM; VU University Medical Center, The Netherlands Judith.sonder@vumc.nl., Balk LJ; VU University Medical Center, The Netherlands., van der Linden FA; VU University Medical Center, The Netherlands., Bosma LV; VU University Medical Center, The Netherlands., Polman CH; VU University Medical Center, The Netherlands., Uitdehaag BM; VU University Medical Center, The Netherlands. |
| المصدر: | Multiple sclerosis (Houndmills, Basingstoke, England) [Mult Scler] 2015 Dec; Vol. 21 (14), pp. 1865-71. Date of Electronic Publication: 2014 Sep 25. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: SAGE Publications Country of Publication: England NLM ID: 9509185 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-0970 (Electronic) Linking ISSN: 13524585 NLM ISO Abbreviation: Mult Scler Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2006- : London : SAGE Publications Original Publication: Houndmills, Basingstoke, Hampshire, UK : Stockton Press, c1995- |
| مواضيع طبية MeSH: | Disease Progression* , Patient Outcome Assessment* , Severity of Illness Index*, Multiple Sclerosis/*diagnosis , Outcome Assessment, Health Care/*methods, Adult ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Outcome Assessment, Health Care/standards |
| مستخلص: | Background: Assessment of disease impact in multiple sclerosis (MS) is usually driven by information obtained directly from patients using patient-reported outcomes. However, when patients' response in longitudinal studies is less reliable or missing, proxy respondents may be used. Objective: The objective of this paper is to evaluate whether long-term patient scores can be reliably estimated using scores obtained from proxies. Methods: Baseline, six-month and two-year data were collected from 155 patients and proxies on the physical scale of the Multiple Sclerosis Impact Scale (MSIS-29). Linear regression analyses were performed with the patient two-year scores as outcome, proxy two-year scores as predictor and other variables that could contribute to a better prediction of the patient follow-up score. Results: The patient follow-up score could be predicted rather accurately (R(2) = 0.74) using the patient baseline score and the proxy follow-up score. The correlation between observed and predicted scores was 0.86. The model performed well in different follow-up durations and even better in an external cohort. Conclusion: A simple model of a constant value (intercept), the patient baseline score and the proxy follow-up score can predict patients' follow-up score on the physical impact of MS. (© The Author(s), 2014.) |
| فهرسة مساهمة: | Keywords: MSIS; Multiple sclerosis; longitudinal research; outcome measurement; patient-reported outcome; proxy |
| تواريخ الأحداث: | Date Created: 20140927 Date Completed: 20160906 Latest Revision: 20191210 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1177/1352458514544078 |
| PMID: | 25257617 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1477-0970 |
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| DOI: | 10.1177/1352458514544078 |