دورية أكاديمية
Developmental toxicity, acute toxicity and mutagenicity testing in freshwater snails Biomphalaria glabrata (Mollusca: Gastropoda) exposed to chromium and water samples.
| العنوان: | Developmental toxicity, acute toxicity and mutagenicity testing in freshwater snails Biomphalaria glabrata (Mollusca: Gastropoda) exposed to chromium and water samples. |
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| المؤلفون: | Tallarico Lde F; Laboratório de Parasitologia/Malacologia, Instituto Butantan, Avenida Vital Brasil, 1500, CEP 05503-900, São Paulo, SP, Brazil; Instituto de Pesquisas Energéticas e Nucleares, IPEN-CNEN/SP, Av. Prof. Lineu Prestes, no 2242, Cidade Universitária, CEP 05508-000, São Paulo, SP, Brazil. Electronic address: letallarico@gmail.com., Borrely SI; Instituto de Pesquisas Energéticas e Nucleares, IPEN-CNEN/SP, Av. Prof. Lineu Prestes, no 2242, Cidade Universitária, CEP 05508-000, São Paulo, SP, Brazil., Hamada N; Instituto de Pesquisas Energéticas e Nucleares, IPEN-CNEN/SP, Av. Prof. Lineu Prestes, no 2242, Cidade Universitária, CEP 05508-000, São Paulo, SP, Brazil., Grazeffe VS; Laboratório de Parasitologia/Malacologia, Instituto Butantan, Avenida Vital Brasil, 1500, CEP 05503-900, São Paulo, SP, Brazil., Ohlweiler FP; Laboratório de Malacologia, Superintendência de Controle de Endemias, Rua Cardeal Arcoverde, no 2878, CEP 05408-003, São Paulo, SP, Brazil., Okazaki K; Instituto de Pesquisas Energéticas e Nucleares, IPEN-CNEN/SP, Av. Prof. Lineu Prestes, no 2242, Cidade Universitária, CEP 05508-000, São Paulo, SP, Brazil., Granatelli AT; Laboratório de Parasitologia/Malacologia, Instituto Butantan, Avenida Vital Brasil, 1500, CEP 05503-900, São Paulo, SP, Brazil., Pereira IW; Companhia de Saneamento Básico do Estado de São Paulo, R. Major Pinheiro Fróes, no 1.560, CEP 08680-000, Suzano, SP, Brazil., Pereira CA; Departamento de Estatística, Instituto de Matemática e Estatística, Universidade de São Paulo, Rua do Matão, no 1010, CEP 05008-090, São Paulo, SP, Brazil., Nakano E; Laboratório de Parasitologia/Malacologia, Instituto Butantan, Avenida Vital Brasil, 1500, CEP 05503-900, São Paulo, SP, Brazil. |
| المصدر: | Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2014 Dec; Vol. 110, pp. 208-15. Date of Electronic Publication: 2014 Sep 26. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7805381 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2414 (Electronic) Linking ISSN: 01476513 NLM ISO Abbreviation: Ecotoxicol Environ Saf Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Amsterdam, Netherlands : Elsevier |
| مواضيع طبية MeSH: | Fresh Water*, Biomphalaria/*drug effects , Chromium/*toxicity , Embryonic Development/*drug effects , Mutagens/*toxicity, Animals ; Biological Assay/methods ; Biomphalaria/embryology ; Biomphalaria/growth & development ; Daphnia/genetics ; Ecotoxicology/methods ; Embryo, Nonmammalian ; Mutagenicity Tests/methods ; Potassium Dichromate/toxicity |
| مستخلص: | A protocol combining acute toxicity, developmental toxicity and mutagenicity analysis in freshwater snail Biomphalaria glabrata for application in ecotoxicological studies is described. For acute toxicity testing, LC50 and EC50 values were determined; dominant lethal mutations induction was the endpoint for mutagenicity analysis. Reference toxicant potassium dichromate (K2Cr2O7) was used to characterize B. glabrata sensitivity for toxicity and cyclophosphamide to mutagenicity testing purposes. Compared to other relevant freshwater species, B. glabrata showed high sensitivity: the lowest EC50 value was obtained with embryos at veliger stage (5.76mg/L). To assess the model applicability for environmental studies, influent and effluent water samples from a wastewater treatment plant were evaluated. Gastropod sensitivity was assessed in comparison to the standardized bioassay with Daphnia similis exposed to the same water samples. Sampling sites identified as toxic to daphnids were also detected by snails, showing a qualitatively similar sensitivity suggesting that B. glabrata is a suitable test species for freshwater monitoring. Holding procedures and protocols implemented for toxicity and developmental bioassays showed to be in compliance with international standards for intra-laboratory precision. Thereby, we are proposing this system for application in ecotoxicological studies. (Copyright © 2014 Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Biomphalaria glabrata; Developmental toxicity; Dominant lethal test; Potassium dichromate; Toxicity |
| المشرفين على المادة: | 0 (Mutagens) 0R0008Q3JB (Chromium) T4423S18FM (Potassium Dichromate) |
| تواريخ الأحداث: | Date Created: 20140927 Date Completed: 20150722 Latest Revision: 20181202 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1016/j.ecoenv.2014.09.005 |
| PMID: | 25259848 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1090-2414 |
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| DOI: | 10.1016/j.ecoenv.2014.09.005 |