دورية أكاديمية

The psychophysiological effects of Tai-chi and exercise in residential schizophrenic patients: a 3-arm randomized controlled trial.

التفاصيل البيبلوغرافية
العنوان: The psychophysiological effects of Tai-chi and exercise in residential schizophrenic patients: a 3-arm randomized controlled trial.
المؤلفون: Ho RT; Centre on Behavioral Health, The University of Hong Kong, 2/F, The Hong Kong Jockey Club Building for Interdisciplinary Research, 5 Sassoon Road, Pokfulam Hong Kong, China. tinho@hku.hk., Wan AH, Au-Yeung FS, Lo PH, Siu PJ, Wong CP, Ng WY, Cheung IK, Ng SM, Chan CL, Chen EY
المصدر: BMC complementary and alternative medicine [BMC Complement Altern Med] 2014 Sep 27; Vol. 14, pp. 364. Date of Electronic Publication: 2014 Sep 27.
نوع المنشور: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101088661 Publication Model: Electronic Cited Medium: Internet ISSN: 1472-6882 (Electronic) Linking ISSN: 14726882 NLM ISO Abbreviation: BMC Complement Altern Med Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central, [2001-2019]
مواضيع طبية MeSH: Exercise Therapy/*methods , Exercise Therapy/*psychology , Schizophrenia/*therapy , Tai Ji/*psychology, Adult ; Exercise/physiology ; Female ; Humans ; Male ; Middle Aged ; Psychophysiology ; Young Adult
مستخلص: Background: Patients with schizophrenia are characterized by high prevalence rates and chronicity that often leads to long-term institutionalization. Under the traditional medical model, treatment usually emphasizes the management of psychotic symptoms through medication, even though anti-psychotic drugs are associated with severe side effects, which can diminish patients' physical and psychological well-being. Tai-chi, a mind-body exercise rooted in Eastern health philosophy, emphasizes the motor coordination and relaxation. With these potential benefits, a randomized controlled trial (RCT) is planned to investigate the effects of Tai-chi intervention on the cognitive and motor deficits characteristic of patients with schizophrenia.
Methods/design: A 3-arm RCT with waitlist control design will be used in this study. One hundred and fifty three participants will be randomized into (i) Tai-chi, (ii) exercise or (iii) waitlist control groups. Participants in both the Tai-chi and exercise groups will receive 12-weeks of specific intervention, in addition to the standard medication and care received by the waitlist control group. The exercise group will serve as a comparison, to delineate any unique benefits of Tai-chi that are independent of moderate aerobic exercise. All three groups will undergo three assessment phases: (i) at baseline, (ii) at 12 weeks (post-intervention), and (iii) at 24 weeks (maintenance). All participants will be assessed in terms of symptom management, motor coordination, memory, daily living function, and stress levels based on self-perceived responses and a physiological marker.
Discussion: Based on a promising pilot study conducted prior to this RCT, subjects in the Tai-chi intervention group are expected to be protected against deterioration of motor coordination and interpersonal functioning. They are also expected to have better symptoms management and lower stress level than the other treatment groups.
Trial Registration: The trail has been registered in the Clinical Trials Center of the University of Hong Kong (HKCTR-1453).
References: Psychol Med. 2011 Mar;41(3):463-76. (PMID: 20529412)
Proc Natl Acad Sci U S A. 1996 Sep 3;93(18):9985-90. (PMID: 8790444)
Br J Sports Med. 2000 Feb;34(1):29-34. (PMID: 10690447)
Psychiatry Clin Neurosci. 2010 Oct;64(5):548-54. (PMID: 20923433)
J Psychosom Res. 1989;33(2):197-206. (PMID: 2724196)
Schizophr Bull. 1987;13(2):261-76. (PMID: 3616518)
J Psychopharmacol. 2010 Nov;24(4 Suppl):37-50. (PMID: 20923919)
Schizophr Res. 2010 Feb;116(2-3):234-42. (PMID: 19751968)
Arch Gen Psychiatry. 2010 Feb;67(2):133-43. (PMID: 20124113)
Arch Gerontol Geriatr. 2011 May-Jun;52(3):357-62. (PMID: 20965096)
Support Care Cancer. 2004 Dec;12(12):871-6. (PMID: 15599776)
Psychol Med. 1999 May;29(3):697-701. (PMID: 10405091)
Evid Based Complement Alternat Med. 2011;2011:383245. (PMID: 19351709)
Home Health Care Serv Q. 2011 Jul;30(3):147-59. (PMID: 21846228)
West J Nurs Res. 2009 Mar;31(2):245-79. (PMID: 19179544)
Md State Med J. 1965 Feb;14:61-5. (PMID: 14258950)
Scand J Soc Med Suppl. 1982;29:259-64. (PMID: 6958049)
J Psychopharmacol. 2010 Nov;24(4 Suppl):91-118. (PMID: 20923924)
JAMA. 2007 Oct 17;298(15):1794-6. (PMID: 17940236)
Schizophr Res. 2011 Jul;129(2-3):122-7. (PMID: 21493044)
J Am Geriatr Soc. 2007 Apr;55(4):511-7. (PMID: 17397428)
Schizophr Res. 2010 Feb;116(2-3):152-8. (PMID: 19942409)
J Altern Complement Med. 2008 Sep;14(7):801-6. (PMID: 18803491)
J Health Soc Behav. 1983 Dec;24(4):385-96. (PMID: 6668417)
Am J Psychiatry. 2004 Aug;161(8):1334-49. (PMID: 15285957)
Psychiatry Res. 1989 Mar;27(3):335-50. (PMID: 2710870)
J Cardiovasc Nurs. 2004 Jan-Feb;19(1):48-57. (PMID: 14994782)
Brain Inj. 2006 Feb;20(2):151-6. (PMID: 16421063)
Altern Ther Health Med. 2012 May-Jun;18(3):16-22. (PMID: 22875558)
J Gerontol B Psychol Sci Soc Sci. 1997 Sep;52(5):P242-6. (PMID: 9310093)
Schizophr Res. 2011 May;128(1-3):23-9. (PMID: 21353766)
تواريخ الأحداث: Date Created: 20140929 Date Completed: 20141222 Latest Revision: 20240321
رمز التحديث: 20240321
مُعرف محوري في PubMed: PMC4189583
DOI: 10.1186/1472-6882-14-364
PMID: 25262346
قاعدة البيانات: MEDLINE
الوصف
تدمد:1472-6882
DOI:10.1186/1472-6882-14-364