دورية أكاديمية
Epidemiology and cost of hospital care for Lyme borreliosis in Germany: lessons from a health care utilization database analysis.
| العنوان: | Epidemiology and cost of hospital care for Lyme borreliosis in Germany: lessons from a health care utilization database analysis. |
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| المؤلفون: | Lohr B; Institute for Laboratory Medicine, Microbiology and Infection Control, Northwest Medical Centre, Academic Teaching Hospital, Medical Faculty, Goethe-University, Steinbacher Hohl 2-26, 60488 Frankfurt am Main, Germany. Electronic address: lohr.benedikt@khnw.de., Müller I; Institute for Laboratory Medicine, Microbiology and Infection Control, Northwest Medical Centre, Academic Teaching Hospital, Medical Faculty, Goethe-University, Steinbacher Hohl 2-26, 60488 Frankfurt am Main, Germany., Mai M; Institute for Laboratory Medicine, Microbiology and Infection Control, Northwest Medical Centre, Academic Teaching Hospital, Medical Faculty, Goethe-University, Steinbacher Hohl 2-26, 60488 Frankfurt am Main, Germany., Norris DE; Department of Molecular Microbiology and Immunology, Johns Hopkins Malaria Research Institute, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA., Schöffski O; Chair for Health Management, Friedrich-Alexander-University Erlangen-Nuremberg, Lange Gasse 20, 90403 Nuremberg, Germany., Hunfeld KP; Institute for Laboratory Medicine, Microbiology and Infection Control, Northwest Medical Centre, Academic Teaching Hospital, Medical Faculty, Goethe-University, Steinbacher Hohl 2-26, 60488 Frankfurt am Main, Germany. |
| المصدر: | Ticks and tick-borne diseases [Ticks Tick Borne Dis] 2015 Feb; Vol. 6 (1), pp. 56-62. Date of Electronic Publication: 2014 Oct 19. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101522599 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1877-9603 (Electronic) Linking ISSN: 1877959X NLM ISO Abbreviation: Ticks Tick Borne Dis Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Amsterdam : Elsevier, 2010- |
| مواضيع طبية MeSH: | Borrelia burgdorferi/*physiology , Lyme Disease/*epidemiology, Adolescent ; Adult ; Aged ; Child ; Child, Preschool ; Cohort Studies ; Female ; Germany/epidemiology ; Hospitalization/economics ; Humans ; Incidence ; Lyme Disease/economics ; Male ; Middle Aged ; Retrospective Studies ; Seasons ; Young Adult |
| مستخلص: | To date, relatively little is known about the economic and medical impact of Lyme borreliosis (LB) on European health care systems, especially for the inpatient sector. This retrospective analysis is based on data provided for the years 2007-2011 by a German statutory health insurance company (DAK-Gesundheit) covering approximately 6 million insured. Total cost was calculated for a 1-year period both from the third-party payers and from the societal perspective, respectively. In our cohort the incident diagnosis of LB was coded for 2163 inpatient cases during the years 2008-2011. The median inpatient time was 9 days resulting in a median direct medical cost per hospital stay of 3917€ for adolescents and 2843€ for adults. Based on extrapolation of our findings to the German population, we would expect an average hospital admission of 5200 adults and 2300 adolescents (<18 years) for LB treatment incurring direct medical costs of more than 23 million Euro annually. The annual indirect costs due to loss of productivity would add up to more than 7 million Euro as assessed by the human capital method. Cases tended to accumulate between June and September with remarkable changes in disease manifestations in the course of the year documented in the coded secondary diagnoses. Also specific differences in the disease pattern of adolescents and adults became obvious. Age-specific incidence showed male predominance and a bimodal distribution. Incidence was highest in children aged between 3 and 17 (highest mean incidence of 29 cases/100,000 inhabitants in 6-9 year olds) with a second peak in 60-79 year old individuals. During the study period the nationwide inpatient incidence was 9/100,000 with marked regional variability. In summary, our study is one of the first European investigations on hospital care for LB inpatients and identifies LB as a possibly underestimated socioeconomic factor for health care in Germany. (Copyright © 2014 Elsevier GmbH. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Costs; Epidemiology; Germany; Health care utilization database; Hospital care; Lyme borreliosis |
| تواريخ الأحداث: | Date Created: 20141203 Date Completed: 20160502 Latest Revision: 20141203 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1016/j.ttbdis.2014.09.004 |
| PMID: | 25448420 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1877-9603 |
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| DOI: | 10.1016/j.ttbdis.2014.09.004 |