دورية أكاديمية
أعرض في EDS

Antifungal properties and inhibitory effects upon aflatoxin production of Thymus vulgaris L. by Aspergillus flavus Link.

التفاصيل البيبلوغرافية
العنوان: Antifungal properties and inhibitory effects upon aflatoxin production of Thymus vulgaris L. by Aspergillus flavus Link.
المؤلفون: Kohiyama CY; Health Sciences Post-Graduate Program, State University of Maringa, Maringa 87020-900, Brazil., Yamamoto Ribeiro MM; Health Sciences Post-Graduate Program, State University of Maringa, Maringa 87020-900, Brazil., Mossini SA; Department of Basic Health Sciences, State University of Maringa, Maringa 87020-900, Brazil., Bando E; Department of Basic Health Sciences, State University of Maringa, Maringa 87020-900, Brazil., Bomfim Nda S; Health Sciences Post-Graduate Program, State University of Maringa, Maringa 87020-900, Brazil., Nerilo SB; Health Sciences Post-Graduate Program, State University of Maringa, Maringa 87020-900, Brazil., Rocha GH; Department of Basic Health Sciences, State University of Maringa, Maringa 87020-900, Brazil., Grespan R; Health Sciences Post-Graduate Program, State University of Maringa, Maringa 87020-900, Brazil., Mikcha JM; Department of Clinical Analysis and Biomedicine, State University of Maringa, Maringa 87020-900, Brazil., Machinski M Jr; Department of Basic Health Sciences, State University of Maringa, Maringa 87020-900, Brazil. Electronic address: mmjunior@uem.br.
المصدر: Food chemistry [Food Chem] 2015 Apr 15; Vol. 173, pp. 1006-10. Date of Electronic Publication: 2014 Nov 03.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE
أسماء مطبوعة: Publication: Barking : Elsevier Applied Science Publishers
Original Publication: Barking, Eng., Applied Science Publishers.
مواضيع طبية MeSH: Aflatoxin B1/*antagonists & inhibitors , Aflatoxins/*antagonists & inhibitors , Antifungal Agents/*pharmacology , Aspergillus flavus/*drug effects , Oils, Volatile/*pharmacology , Thymus Plant/*metabolism, Aflatoxin B1/biosynthesis ; Aflatoxins/biosynthesis
مستخلص: The antifungal and antiaflatoxigenic properties of Thymus vulgaris essential oil (TEO) were evaluated upon Aspergillus flavus "in vitro". Suspension containing 10(6) of A. flavus were cultivated with TEO in concentrations ranging from 50 to 500 μg/mL. TEO reached minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) at 250 μg/mL. Inhibition of ergosterol biosynthesis was detected at a concentration of 100 μg/mL of TEO. Morphological evaluation performed by both light microscopy and scanning electron microscopy showed that antifungal activity of TEO could be detected starting at a concentration of 50 μg/mL and the fungicide effect at a concentration of 250 μg/mL. TEO completely inhibited production of both B1 and B2 aflatoxins (AFB1 and AFB2) at a concentration of 150 μg/mL. This way, fungal biomass development and aflatoxin production were dependent on TEO concentration. Therefore, TEO was capable of controlling the growth of A. flavus and its production of aflatoxins.
(Copyright © 2014 Elsevier Ltd. All rights reserved.)
فهرسة مساهمة: Keywords: Antifungal; Aspergillus flavus; Ergosterol; Mycotoxins; Thyme essential oil
المشرفين على المادة: 0 (Aflatoxins)
0 (Antifungal Agents)
0 (Oils, Volatile)
7SKR7S646P (aflatoxin B2)
9N2N2Y55MH (Aflatoxin B1)
تواريخ الأحداث: Date Created: 20141204 Date Completed: 20150804 Latest Revision: 20181202
رمز التحديث: 20231215
DOI: 10.1016/j.foodchem.2014.10.135
PMID: 25466118
قاعدة البيانات: MEDLINE
الوصف
تدمد:1873-7072
DOI:10.1016/j.foodchem.2014.10.135