دورية أكاديمية

Pattern of childhood leukaemia in University College Hospital, Ibadan.

التفاصيل البيبلوغرافية
العنوان: Pattern of childhood leukaemia in University College Hospital, Ibadan.
المؤلفون: Babatunde TO, Ogun GO, Brown BJ, Akang EE, Aken'Ova YA
المصدر: African journal of medicine and medical sciences [Afr J Med Med Sci] 2014 Jun; Vol. 43 (2), pp. 135-8.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: College of Medicine, University of Ibadan and the University College Hospital Country of Publication: Nigeria NLM ID: 7801013 Publication Model: Print Cited Medium: Print ISSN: 0309-3913 (Print) Linking ISSN: 03093913 NLM ISO Abbreviation: Afr J Med Med Sci Subsets: MEDLINE
أسماء مطبوعة: Publication: Sept.1996- : Ibadan : College of Medicine, University of Ibadan and the University College Hospital.
Original Publication: Oxford, Blackwell Scientific Publications
مواضيع طبية MeSH: Leukemia/*epidemiology, Adolescent ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Leukemia, Myeloid, Acute/epidemiology ; Male ; Nigeria/epidemiology ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/epidemiology ; Retrospective Studies ; Urban Population/statistics & numerical data
مستخلص: Background: Leukaemias are haematological malignancies characterized by unregulated clonal proliferation of haematopoietic cells.
Objective: To determine the pattern of childhood leukaemia in Ibadan.
Methodology: This was a retrospective study of leukaemia cases diagnosed at the University College Hospital (UCH), Ibadan between January 1991 and December 2010 in children less than 15 years of age. Data obtained was subjected to statistical analysis using the Statistical Package for Social Sciences version 20.
Results: There were 64 cases of childhood leukaemia, accounting for 10.2% of childhood cancers seen during this study period. The male to female ratio was 2:1 and modal age group was between 10 and 14 years. Thirty (46.9%) cases were acute lymphoblastic leukaemia (ALL), 22 (34.4%) were acute myelogenous leukaemia (AML) and 12 (18.8%) were unspecified acute leukaemias. There was no case of chronic myeloid or lymphocytic leukaemia.
Conclusion: There has been a relative increase in the frequency of leukaemia cases at UCH, Ibadan, which may be largely explained by increased awareness and referrals. There is a need for further collaborative multicentre studies of childhood leukaemias in Nigeria and other developing countries and focused research on childhood leukaemias in order to unravel the aetiology.
تواريخ الأحداث: Date Created: 20141206 Date Completed: 20150113 Latest Revision: 20180718
رمز التحديث: 20231215
PMID: 25474988
قاعدة البيانات: MEDLINE