دورية أكاديمية
أعرض في EDS

Integrative medicine for subacute stroke rehabilitation: a study protocol for a multicentre, randomised, controlled trial.

التفاصيل البيبلوغرافية
العنوان: Integrative medicine for subacute stroke rehabilitation: a study protocol for a multicentre, randomised, controlled trial.
المؤلفون: Fang J; Department of Acupuncture, The Third Affiliated Hospital of Zhejiang Traditional Chinese Medical University, Hangzhou, Zhejiang, China The Third Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Chen L; Department of Acupuncture, The Third Affiliated Hospital of Zhejiang Traditional Chinese Medical University, Hangzhou, Zhejiang, China., Chen L; The Third Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Wang C; The Third Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Keeler CL; Department of Innovations to Wellness, Affiliated with Five Branches University, San Jose, California, USA., Ma R; Department of Acupuncture, The Third Affiliated Hospital of Zhejiang Traditional Chinese Medical University, Hangzhou, Zhejiang, China., Xu S; Department of Rehabilitation, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Shen L; Department of Acupuncture & Encephalopathy, Jiaxing Hospital of Traditional Chinese Medicine, Jiaxing, Zhejiang, China., Bao Y; Department of Acupuncture & Rehabilitation, Hangzhou Hospital of Traditional Chinese Medicine, Hangzhou, Zhejiang, China., Ji C; The Clinical Research Institute of Zhejiang Provincial Hospital of Traditional Chinese Medicine, Hangzhou, Zhejiang, China.
المصدر: BMJ open [BMJ Open] 2014 Dec 04; Vol. 4 (12), pp. e007080. Date of Electronic Publication: 2014 Dec 04.
نوع المنشور: Journal Article; Multicenter Study; Randomized Controlled Trial
اللغة: English
بيانات الدورية: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [London] : BMJ Publishing Group Ltd, 2011-
مواضيع طبية MeSH: Stroke Rehabilitation*, Integrative Medicine/*methods, Acupuncture Therapy/methods ; Adult ; Aged ; Aged, 80 and over ; Drugs, Chinese Herbal/therapeutic use ; Female ; Humans ; Male ; Middle Aged ; Single-Blind Method ; Treatment Outcome
مستخلص: Introduction: Many patients with stroke receive integrative medicine in China, which includes the basic treatment of Western medicine and routine rehabilitation, in conjunction with acupuncture and Chinese medicine. The question of whether integrative medicine is efficacious for stroke rehabilitation is still controversial and very little research currently exists on the integrated approach for this condition. Consequently, we will conduct a multicentre, randomised, controlled, assessor-blinded clinical trial to assess the effectiveness of integrative medicine on stroke rehabilitation.
Methods and Analysis: 360 participants recruited from three large Chinese medical hospitals in Zhejiang Province will be randomly divided into the integrative medicine rehabilitation (IMR) group and the conventional rehabilitation (CR) group in a 1:1 ratio. Participants in the IMR group will receive acupuncture and Chinese herbs in addition to basic Western medicine and rehabilitation treatment. The CR group will not receive acupuncture and Chinese herbal medicine. The assessment data will be collected at baseline, 4 and 8 weeks postrandomisation, and then at 12 weeks' follow-up. The primary outcome is measured by the Modified Barthel Index. The secondary outcomes are the National Institutes of Health Stroke Scale (NIHSS), Fugl-Meyer Assessment, the mini-mental state examination and Montreal Cognitive, Hamilton's Depression Scale and Self-Rating Depression Scale, and the incidence of adverse events.
Ethics and Dissemination: Ethical approval was obtained from ethics committees of three hospitals. The results will be disseminated in a peer-reviewed journal and presented at international congresses. The results will also be disseminated to patients by telephone, during follow-up calls inquiring on patient's post-study health status.
Trial Registration Number: Chinese Clinical Trial Register: ChiCTR-TRC-12001972, http://www.chictr.org/en/proj/show.aspx?proj=2561.
(Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.)
References: Evid Based Complement Alternat Med. 2012;2012:268542. (PMID: 22550539)
Md State Med J. 1965 Feb;14:61-5. (PMID: 14258950)
Phys Ther. 1988 Jul;68(7):1077-81. (PMID: 3387463)
Phys Ther. 1993 Jul;73(7):447-54. (PMID: 8316578)
Stroke. 2009 Aug;40(8):2797-804. (PMID: 19556527)
Cochrane Database Syst Rev. 2005 Apr 18;(2):CD003317. (PMID: 15846657)
Lancet Neurol. 2004 Jul;3(7):391-3. (PMID: 15207791)
Stroke. 1998 Oct;29(10):2100-8. (PMID: 9756589)
Stroke. 2011 Dec;42(12):3651-4. (PMID: 22052510)
Explore (NY). 2009 Sep-Oct;5(5):277-89. (PMID: 19733814)
Trends Pharmacol Sci. 1999 May;20(5):191-6. (PMID: 10354613)
Arch Intern Med. 2005 Sep 26;165(17):2026-31. (PMID: 16186474)
Int Clin Psychopharmacol. 2008 May;23(3):120-9. (PMID: 18408526)
Stroke. 2007 Jun;38(6):1973-9. (PMID: 17463317)
Neurology. 1999 Jul 13;53(1):126-31. (PMID: 10408548)
Int J Geriatr Psychiatry. 1997 Jan;12(1):101-8. (PMID: 9050431)
Lancet. 2005 Nov 19;366(9499):1821-4. (PMID: 16298221)
J Am Geriatr Soc. 2005 Apr;53(4):695-9. (PMID: 15817019)
CMAJ. 2005 Nov 22;173(11):1327-34. (PMID: 16301700)
Stroke. 2011 Feb;42(2):427-32. (PMID: 21164120)
Stroke. 1997 Feb;28(2):307-10. (PMID: 9040680)
Int Disabil Stud. 1988;10(2):61-3. (PMID: 3403500)
Arch Gen Psychiatry. 1998 Jan;55(1):82-3. (PMID: 9435764)
Arch Phys Med Rehabil. 1979 Jan;60(1):14-7. (PMID: 420565)
Stroke. 2002 Nov;33(11):2604-19. (PMID: 12411650)
Stroke. 2008 Jun;39(6):1668-74. (PMID: 18309149)
Lancet Neurol. 2007 May;6(5):456-64. (PMID: 17434100)
فهرسة مساهمة: Keywords: COMPLEMENTARY MEDICINE; STROKE MEDICINE
المشرفين على المادة: 0 (Drugs, Chinese Herbal)
تواريخ الأحداث: Date Created: 20141206 Date Completed: 20150721 Latest Revision: 20240322
رمز التحديث: 20240322
مُعرف محوري في PubMed: PMC4256536
DOI: 10.1136/bmjopen-2014-007080
PMID: 25475247
قاعدة البيانات: MEDLINE
الوصف
تدمد:2044-6055
DOI:10.1136/bmjopen-2014-007080