دورية أكاديمية
Neutrophil-lymphocyte ratio as a predictive factor for tumor staging in colorectal cancer.
| العنوان: | Neutrophil-lymphocyte ratio as a predictive factor for tumor staging in colorectal cancer. |
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| المؤلفون: | Özgehan G; Dışkapı Yıldırım Beyazit Education and Research Hospital, Ankara, Turkey., Kahramanca Ş, Kaya İO, Bilgen K, Bostanci H, Güzel H, Küçükpinar T, Kargici H |
| المصدر: | Turkish journal of medical sciences [Turk J Med Sci] 2014; Vol. 44 (3), pp. 365-8. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Scientific and Technical Research Council of Turkey Country of Publication: Turkey NLM ID: 9441758 Publication Model: Print Cited Medium: Print ISSN: 1300-0144 (Print) Linking ISSN: 13000144 NLM ISO Abbreviation: Turk J Med Sci Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Ankara : Scientific and Technical Research Council of Turkey, [1994- |
| مواضيع طبية MeSH: | Colorectal Neoplasms/*blood , Colorectal Neoplasms/*pathology , Lymphocytes/*pathology , Neutrophils/*pathology, Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Leukocyte Count ; Male ; Middle Aged ; Neoplasm Staging ; Predictive Value of Tests ; Young Adult |
| مستخلص: | Background/aim: In the preoperative period, simple methods to identify the tumor stage of colorectal cancer patients are needed. In recent years, the neutrophil-lymphocyte ratio (NLR) has been used as a predictive parameter for systemic inflammatory response in many different clinical entities. This study aims to determine if the NLR predicts the tumor stage in colorectal cancer patients in the preoperative period. Materials and Methods: A total of 206 patients diagnosed with colorectal cancer and admitted for surgical treatment over a 6-year period were identified from a retrospectively maintained database. NLR was calculated from preoperative full blood counts. NLRs were compared with the tumor stages as determined in histopathological reports and scanning tests to determine the extent of metastasis. Results: We found NLRs to be statistically higher in patients with T3 and T4 tumors than in patients with T1 and T2 tumors (mean: 5.261 vs. 4.499, respectively, P = 0.010). Similarly, we found statistically higher NLR values in the N1 and N2 groups than in the NO group (mean: 6.597 vs. 4.501, respectively, P < 0.001). Additionally, NLRs were statistically higher in M1 patients than in MO patients (mean: 8.261 vs. 5.158, respectively, P = 0.004). Conclusion: In the preoperative period, NLR was found to be a valuable predictive parameter for tumor staging in patients with colorectal cancer, thus informing us as to the kind of tumor we will meet when we open the abdomen. |
| تواريخ الأحداث: | Date Created: 20150107 Date Completed: 20150304 Latest Revision: 20191113 |
| رمز التحديث: | 20221213 |
| DOI: | 10.3906/sag-1305-33 |
| PMID: | 25558634 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1300-0144 |
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| DOI: | 10.3906/sag-1305-33 |