دورية أكاديمية
Tolerance of benznidazole in a United States Chagas Disease clinic.
| العنوان: | Tolerance of benznidazole in a United States Chagas Disease clinic. |
|---|---|
| المؤلفون: | Miller DA; Los Angeles Biomedical Research Division of Infectious Diseases, Harbor-UCLA Medical Center, Torrance., Hernandez S; Center of Excellence for Chagas Disease, Olive View-UCLA Medical Center, Sylmar, California., Rodriguez De Armas L; Center of Excellence for Chagas Disease, Olive View-UCLA Medical Center, Sylmar, California., Eells SJ; Los Angeles Biomedical Research Division of Infectious Diseases, Harbor-UCLA Medical Center, Torrance., Traina MM; Center of Excellence for Chagas Disease, Olive View-UCLA Medical Center, Sylmar, California., Miller LG; Los Angeles Biomedical Research Division of Infectious Diseases, Harbor-UCLA Medical Center, Torrance., Meymandi SK; Center of Excellence for Chagas Disease, Olive View-UCLA Medical Center, Sylmar, California. |
| المصدر: | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2015 Apr 15; Vol. 60 (8), pp. 1237-40. Date of Electronic Publication: 2015 Jan 18. |
| نوع المنشور: | Journal Article; Observational Study; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Oxford University Press Country of Publication: United States NLM ID: 9203213 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-6591 (Electronic) Linking ISSN: 10584838 NLM ISO Abbreviation: Clin Infect Dis Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Jan. 2011- : Oxford : Oxford University Press Original Publication: Chicago, IL : The University of Chicago Press, c1992- |
| مواضيع طبية MeSH: | Chagas Disease/*drug therapy , Drug-Related Side Effects and Adverse Reactions/*epidemiology , Nitroimidazoles/*adverse effects , Trypanocidal Agents/*adverse effects, Adolescent ; Adult ; Aged ; Angioedema/chemically induced ; Angioedema/epidemiology ; Female ; Humans ; Male ; Middle Aged ; Nitroimidazoles/therapeutic use ; Peripheral Nervous System Diseases/chemically induced ; Peripheral Nervous System Diseases/epidemiology ; Retrospective Studies ; Trypanocidal Agents/therapeutic use ; United States ; Young Adult |
| مستخلص: | The US-based Center of Excellence for Chagas Disease performed an observational study on the safety and tolerance of benznidazole 5 mg/kg/day for 60 days in 30 adults with chronic Chagas disease. The side-effect profile was suboptimal, including 5 cases of debilitating neuropathy and an unusually high angioedema rate. (© The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.) |
| التعليقات: | Comment in: Clin Infect Dis. 2015 Jun 15;60(12):1873-5. (PMID: 25805302) Comment in: Clin Infect Dis. 2015 Jun 15;60(12):1875-6. (PMID: 25805304) Comment in: Clin Infect Dis. 2016 Apr 15;62(8):1052. (PMID: 26769725) |
| فهرسة مساهمة: | Keywords: Chagas disease; United States; benznidazole; drug tolerance; trypanosomiasis |
| المشرفين على المادة: | 0 (Nitroimidazoles) 0 (Trypanocidal Agents) YC42NRJ1ZD (benzonidazole) |
| تواريخ الأحداث: | Date Created: 20150121 Date Completed: 20151214 Latest Revision: 20220321 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1093/cid/civ005 |
| PMID: | 25601454 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1537-6591 |
|---|---|
| DOI: | 10.1093/cid/civ005 |