دورية أكاديمية
أعرض في EDS

Niobium pentoxide as radiopacifying agent of calcium silicate-based material: evaluation of physicochemical and biological properties.

التفاصيل البيبلوغرافية
العنوان: Niobium pentoxide as radiopacifying agent of calcium silicate-based material: evaluation of physicochemical and biological properties.
المؤلفون: Silva GF; Department of Restorative Dentistry, UNESP-Univ. Estadual Paulista, Dental School, Araraquara, SP, Brazil., Tanomaru-Filho M; Department of Restorative Dentistry, UNESP-Univ. Estadual Paulista, Dental School, Araraquara, SP, Brazil., Bernardi MI; Physics Institute of São Carlos, Grupo Crescimento de Cristais e Materiais Cerâmicos, University of São Paulo-USP, São Carlos, SP, Brazil., Guerreiro-Tanomaru JM; Department of Restorative Dentistry, UNESP-Univ. Estadual Paulista, Dental School, Araraquara, SP, Brazil., Cerri PS; Laboratory of Histology and Embryology, UNESP-Univ. Estadual Paulista, Dental School, Araraquara, SP, Brazil. pcerri@foar.unesp.br.; Department of Morphology-Laboratory of Histology and Embryology, UNESP-Univ Estadual Paulista, Dental School, Rua Humaitá, 1680, Centro, CEP, 14801-903, Araraquara, SP, Brazil. pcerri@foar.unesp.br.
المصدر: Clinical oral investigations [Clin Oral Investig] 2015 Nov; Vol. 19 (8), pp. 2015-25. Date of Electronic Publication: 2015 Feb 03.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 9707115 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1436-3771 (Electronic) Linking ISSN: 14326981 NLM ISO Abbreviation: Clin Oral Investig
أسماء مطبوعة: Publication: Berlin : Springer-Verlag
Original Publication: Berlin : Springer, c1997-
مواضيع طبية MeSH: Calcium Compounds*/chemistry , Calcium Compounds*/pharmacology , Contrast Media*/chemistry , Contrast Media*/pharmacology , Dental Cements*/chemistry , Dental Cements*/pharmacology , Materials Testing* , Niobium*/chemistry , Niobium*/pharmacology , Oxides*/chemistry , Oxides*/pharmacology , Silicates*/chemistry , Silicates*/pharmacology, Animals ; Rats
مستخلص: Objectives: The physicochemical properties and the tissue reaction promoted by microparticulated or nanoparticulated niobium pentoxide (Nb2O5) added to calcium silicate-based cement (CS), compared to MTA-Angelus™, were evaluated.
Materials and Methods: Materials were submitted to the tests of radiopacity, setting time, pH, and calcium ion release. Polyethylene tubes filled with the materials were implanted into rats subcutaneously. After 7, 15, 30, and 60 days, the specimens were fixed and embedded in paraffin. Hematoxylin & eosin (H&E)-stained sections were used to compute the number of inflammatory cells (IC). Interleukin-6 (IL-6) detection was performed, and the number of immunolabeled cells was obtained; von Kossa method was also carried out. Data were subjected to ANOVA and Tukey test (p ≤ 0.05).
Results: Nb2O5micro and Nb2O5nano provided to the CS radiopacity values (3.52 and 3.75 mm Al, respectively) superior to the minimum recommended. Groups containing Nb2O5 presented initial setting time significantly superior than mineral trioxide aggregate (MTA). All materials presented an alkaline pH and released calcium ions. The number of IC and IL-6 immunolabeled cells in the CS + Nb2O5 groups was significantly reduced in comparison to MTA in all periods. von Kossa-positive structures were observed adjacent to implanted materials in all periods.
Conclusions: The addition of Nb2O5 to the CS resulted in a material biocompatible and with adequate characteristics regarding radiopacity and final setting time and provides an alkaline pH to the environment. Furthermore, the particle size did not significantly affect the physicochemical and biological properties of the calcium silicate-based cement.
Clinical Relevance: Niobium pentoxide can be used as radiopacifier for the development of calcium silicate-based materials.
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فهرسة مساهمة: Keywords: Biocompatibility; Calcium silicate cement; Mineral trioxide aggregate; Physicochemical properties; Radiopacifiers
المشرفين على المادة: 0 (Calcium Compounds)
0 (Contrast Media)
0 (Dental Cements)
0 (Oxides)
0 (Silicates)
05175J654G (Niobium)
K9343U17IN (niobium pentoxide)
S4255P4G5M (calcium silicate)
تواريخ الأحداث: Date Created: 20150204 Date Completed: 20170106 Latest Revision: 20181113
رمز التحديث: 20231215
DOI: 10.1007/s00784-015-1412-9
PMID: 25644135
قاعدة البيانات: MEDLINE
الوصف
تدمد:1436-3771
DOI:10.1007/s00784-015-1412-9