دورية أكاديمية
New reference charts for testicular volume in Dutch children and adolescents allow the calculation of standard deviation scores.
| العنوان: | New reference charts for testicular volume in Dutch children and adolescents allow the calculation of standard deviation scores. |
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| المؤلفون: | Joustra SD; Department of Pediatrics, Leiden University Medical Center, Leiden, Netherlands.; Department of Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, Netherlands., van der Plas EM; Department of Pediatrics, Medical Centre Alkmaar, Alkmaar, Netherlands., Goede J; Department of Pediatrics, Medical Centre Alkmaar, Alkmaar, Netherlands., Oostdijk W; Department of Pediatrics, Leiden University Medical Center, Leiden, Netherlands., Delemarre-van de Waal HA; Department of Pediatrics, Leiden University Medical Center, Leiden, Netherlands., Hack WW; Department of Pediatrics, Medical Centre Alkmaar, Alkmaar, Netherlands., van Buuren S; Netherlands Organisation for Applied Scientific Research TNO, Leiden, Netherlands.; Department of Methodology and Statistics, FSBS, University of Utrecht, Utrecht, Netherlands., Wit JM; Department of Pediatrics, Leiden University Medical Center, Leiden, Netherlands. |
| المصدر: | Acta paediatrica (Oslo, Norway : 1992) [Acta Paediatr] 2015 Jun; Vol. 104 (6), pp. e271-8. Date of Electronic Publication: 2015 Mar 11. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley-Blackwell Country of Publication: Norway NLM ID: 9205968 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1651-2227 (Electronic) Linking ISSN: 08035253 NLM ISO Abbreviation: Acta Paediatr Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2007- : Oslo : Wiley-Blackwell Original Publication: Oslo : Scandinavian University Press, c1992- |
| مواضيع طبية MeSH: | Testis/*anatomy & histology, Adolescent ; Child ; Child, Preschool ; Growth Charts ; Humans ; Infant ; Male ; Netherlands ; Organ Size ; Reference Values ; Sexual Development ; Young Adult |
| مستخلص: | Aim: Accurate calculations of testicular volume standard deviation (SD) scores are not currently available. We constructed LMS-smoothed age-reference charts for testicular volume in healthy boys. Methods: The LMS method was used to calculate reference data, based on testicular volumes from ultrasonography and Prader orchidometer of 769 healthy Dutch boys aged 6 months to 19 years. We also explored the association between testicular growth and pubic hair development, and data were compared to orchidometric testicular volumes from the 1997 Dutch nationwide growth study. Results: The LMS-smoothed reference charts showed that no revision of the definition of normal onset of male puberty - from nine to 14 years of age - was warranted. In healthy boys, the pubic hair stage SD scores corresponded with testicular volume SD scores (r = 0.394). However, testes were relatively small for pubic hair stage in Klinefelter's syndrome and relatively large in immunoglobulin superfamily member 1 deficiency syndrome. Conclusion: The age-corrected SD scores for testicular volume will aid in the diagnosis and follow-up of abnormalities in the timing and progression of male puberty and in research evaluations. The SD scores can be compared with pubic hair SD scores to identify discrepancies between cell functions that result in relative microorchidism or macroorchidism. (©2015 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.) |
| فهرسة مساهمة: | Keywords: LMS; Orchidometer; Reference values; Testis; Ultrasonography |
| تواريخ الأحداث: | Date Created: 20150210 Date Completed: 20160301 Latest Revision: 20220408 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1111/apa.12972 |
| PMID: | 25664405 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1651-2227 |
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| DOI: | 10.1111/apa.12972 |