دورية أكاديمية

Sun exposure and vitamin D supplementation in relation to vitamin D status of breastfeeding mothers and infants in the global exploration of human milk study.

التفاصيل البيبلوغرافية
العنوان: Sun exposure and vitamin D supplementation in relation to vitamin D status of breastfeeding mothers and infants in the global exploration of human milk study.
المؤلفون: Dawodu A; Global Health Center, Perinatal Institute and Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA. adekunle.dawodu@cchmc.org., Davidson B; Global Health Center, Perinatal Institute and Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA. barbara.davidson@cchmc.org., Woo JG; Global Health Center, Perinatal Institute and Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA. jessica.woo@cchmc.org., Peng YM; Children's Hospital of Fudan University, 399 Wanyuan Road, Shanghai 20102, China. ympeng@fudan.edu.cn., Ruiz-Palacios GM; National Institute of Medical Sciences and Nutrition, Vasco de Quiroga No. 15, Tlalpan, Mexico City 14000, Mexico. mlga08@gmail.com., de Lourdes Guerrero M; National Institute of Medical Sciences and Nutrition, Vasco de Quiroga No. 15, Tlalpan, Mexico City 14000, Mexico. mlga08@gmail.com., Morrow AL; Global Health Center, Perinatal Institute and Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA. ardythe.morrow@cchmc.org.
المصدر: Nutrients [Nutrients] 2015 Feb 05; Vol. 7 (2), pp. 1081-93. Date of Electronic Publication: 2015 Feb 05.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI Publishing
مواضيع طبية MeSH: Breast Feeding* , Infant* , Mothers* , Sunlight*, Vitamin D/*administration & dosage , Vitamin D Deficiency/*diet therapy, Adult ; Calcifediol/blood ; China/epidemiology ; Dietary Supplements ; Female ; Humans ; Infant Formula/administration & dosage ; Lactation/blood ; Longitudinal Studies ; Male ; Mexico/epidemiology ; Postpartum Period/blood ; Pregnancy ; Prevalence ; Prospective Studies ; Risk Factors ; Seasons ; United States/epidemiology ; Vitamin D/blood ; Vitamin D Deficiency/blood ; Vitamin D Deficiency/epidemiology ; Young Adult
مستخلص: Although vitamin D (vD) deficiency is common in breastfed infants and their mothers during pregnancy and lactation, a standardized global comparison is lacking. We studied the prevalence and risk factors for vD deficiency using a standardized protocol in a cohort of breastfeeding mother-infant pairs, enrolled in the Global Exploration of Human Milk Study, designed to examine longitudinally the effect of environment, diet and culture. Mothers planned to provide breast milk for at least three months post-partum and were enrolled at four weeks postpartum in Shanghai, China (n=112), Cincinnati, Ohio (n=119), and Mexico City, Mexico (n=113). Maternal serum 25(OH)D was measured by radioimmunoassay (<50 nmol/L was categorized as deficient). Serum 25(OH)D was measured in a subset of infants (35 Shanghai, 47 Cincinnati and 45 Mexico City) seen at 26 weeks of age during fall and winter seasons. Data collected prospectively included vD supplementation, season and sun index (sun exposure×body surface area exposed while outdoors). Differences and factors associated with vD deficiency were evaluated using appropriate statistical analysis. vD deficiency in order of magnitude was identified in 62%, 52% and 17% of Mexican, Shanghai and Cincinnati mothers, respectively (p<0.001). In regression analysis, vD supplementation (p<0.01), obesity (p=0.03), season (p=0.001) and sites (p<0.001) predicted maternal vD status. vD deficiency in order of magnitude was found in 62%, 28%, and 6% of Mexican, Cincinnati and Shanghai infants, respectively (p<0.001). Season (p=0.022), adding formula feeding (p<0.001) and a higher sun index (p=0.085) predicted higher infant vD status. vD deficiency appears to be a global problem in mothers and infants, though the prevalence in diverse populations may depend upon sun exposure behaviors and vD supplementation. Greater attention to maternal and infant vD status starting during pregnancy is warranted worldwide.
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معلومات مُعتمدة: P01 HD013021 United States HD NICHD NIH HHS; P30 DK078392 United States DK NIDDK NIH HHS; HD13021 United States HD NICHD NIH HHS
المشرفين على المادة: 1406-16-2 (Vitamin D)
P6YZ13C99Q (Calcifediol)
تواريخ الأحداث: Date Created: 20150210 Date Completed: 20151007 Latest Revision: 20181113
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC4344576
DOI: 10.3390/nu7021081
PMID: 25665158
قاعدة البيانات: MEDLINE
الوصف
تدمد:2072-6643
DOI:10.3390/nu7021081