التفاصيل البيبلوغرافية
| العنوان: |
Amplification of chirality through self-replication of micellar aggregates in water. |
| المؤلفون: |
Bukhryakov KV; KAUST Catalysis Center and Division of Physical Sciences and Engineering, King Abdullah University of Science and Technology, Thuwal 23955-6900, Kingdom of Saudi Arabia., Almahdali S; KAUST Catalysis Center and Division of Physical Sciences and Engineering, King Abdullah University of Science and Technology, Thuwal 23955-6900, Kingdom of Saudi Arabia., Rodionov VO; KAUST Catalysis Center and Division of Physical Sciences and Engineering, King Abdullah University of Science and Technology, Thuwal 23955-6900, Kingdom of Saudi Arabia. |
| المصدر: |
Langmuir : the ACS journal of surfaces and colloids [Langmuir] 2015 Mar 17; Vol. 31 (10), pp. 2931-5. Date of Electronic Publication: 2015 Mar 05. |
| نوع المنشور: |
Journal Article |
| اللغة: |
English |
| بيانات الدورية: |
Publisher: American Chemical Society Country of Publication: United States NLM ID: 9882736 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5827 (Electronic) Linking ISSN: 07437463 NLM ISO Abbreviation: Langmuir Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: |
Original Publication: Washington, DC : American Chemical Society, c1985- |
| مستخلص: |
We describe a system in which the self-replication of micellar aggregates results in a spontaneous amplification of chirality in the reaction products. In this system, amphiphiles are synthesized from two "clickable" fragments: a water-soluble "head" and a hydrophobic "tail". Under biphasic conditions, the reaction is autocatalytic, as aggregates facilitate the transfer of hydrophobic molecules to the aqueous phase. When chiral, partially enantioenriched surfactant heads are used, a strong nonlinear induction of chirality in the reaction products is observed. Preseeding the reaction mixture with an amphiphile of one chirality results in the amplification of this product and therefore information transfer between generations of self-replicating aggregates. Because our amphiphiles are capable of catalysis, information transfer, and self-assembly into bounded structures, they present a plausible model for prenucleic acid "lipid world" entities. |
| تواريخ الأحداث: |
Date Created: 20150306 Date Completed: 20150512 Latest Revision: 20150317 |
| رمز التحديث: |
20240628 |
| DOI: |
10.1021/la504984j |
| PMID: |
25740116 |
| قاعدة البيانات: |
MEDLINE |
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