دورية أكاديمية
[Functional states of the antioxidant enzymatic complex of tissues of Mytilus galloprovincialis Lam. under conditions of oxidative stress].
| العنوان: | [Functional states of the antioxidant enzymatic complex of tissues of Mytilus galloprovincialis Lam. under conditions of oxidative stress]. |
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| المؤلفون: | Soldatov AA, Gostyukhina OL, Golovina IV |
| المصدر: | Zhurnal evoliutsionnoi biokhimii i fiziologii [Zh Evol Biokhim Fiziol] 2014 May-Jun; Vol. 50 (3), pp. 183-9. |
| نوع المنشور: | English Abstract; Journal Article; Review |
| اللغة: | Russian |
| بيانات الدورية: | Publisher: Izdatelstvo Nauka Country of Publication: Russia (Federation) NLM ID: 21820250R Publication Model: Print Cited Medium: Print ISSN: 0044-4529 (Print) Linking ISSN: 00444529 NLM ISO Abbreviation: Zh Evol Biokhim Fiziol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Moscow Izdatelstvo Nauka |
| مواضيع طبية MeSH: | Oxidative Stress*, Catalase/*metabolism , Glutathione Peroxidase/*metabolism , Glutathione Reductase/*metabolism , Mytilus/*enzymology, Adaptation, Physiological ; Animals ; Mytilus/metabolism |
| مستخلص: | There are generalized materials on reaction of enzymatic antioxidant (AO) complex of tissues of molluscs of the genus Mytilus to oxidative loading of different intensity. It is shown that with increase of level of oxidative stress, a rise of activity of glutathione peroxidase (GP) and glutathione reductase (GR) is observed, as well as the rate of glutathione (GSH) in tissues also increases. Then the toxic loading is compensated by a rise of activities of enzymes of low affinity to hydroperoxides, specifically of catalase. In the glutathione system, it is possible to identify several relatively steady states: of low, moderate, and highly intensive processes. In several tissues, functioning of the AO system seems to be directed not to rendering harmless, but to generation of reactive oxygen species (O2-, superoxide dismutase), which is likely to be determined by specificity of their running processes (destruction of damaged byssus theads). The molluscan AO complex is characterized by high lability and sensitivity both to physiological states (spawning) and to action of factors of anthropogenic nature (cationic detergents). Reactions of AO complex of the mussel to the natural states and to toxic action are comparable between each other, which is necessary to be taken into account at diagnostics of the aquatic medium. |
| المشرفين على المادة: | EC 1.11.1.6 (Catalase) EC 1.11.1.9 (Glutathione Peroxidase) EC 1.8.1.7 (Glutathione Reductase) |
| تواريخ الأحداث: | Date Created: 20150318 Date Completed: 20150505 Latest Revision: 20150317 |
| رمز التحديث: | 20240628 |
| PMID: | 25775851 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0044-4529 |
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