دورية أكاديمية
[A potentially fatal intoxication with colchicine].
| العنوان: | [A potentially fatal intoxication with colchicine]. |
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| عنوان ترانسليتريتد: | Een levensbedreigende intoxicatie met colchicine. |
| المؤلفون: | Boonstra JJ; Universitair Medisch Centrum Utrecht, Utrecht., Kan AA, de Vries I, Deneer VH, Meinders AJ |
| المصدر: | Nederlands tijdschrift voor geneeskunde [Ned Tijdschr Geneeskd] 2015; Vol. 159, pp. A8144. |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | Dutch; Flemish |
| بيانات الدورية: | Publisher: Vereniging NTvG Country of Publication: Netherlands NLM ID: 0400770 Publication Model: Print Cited Medium: Internet ISSN: 1876-8784 (Electronic) Linking ISSN: 00282162 NLM ISO Abbreviation: Ned Tijdschr Geneeskd Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2017?-: Amsterdam : Vereniging NTvG Original Publication: Houten : Bohn Stafleu van Loghum |
| مواضيع طبية MeSH: | Suicide, Attempted*, Charcoal/*therapeutic use , Colchicine/*poisoning, Abdominal Pain/chemically induced ; Adolescent ; Charcoal/chemistry ; Critical Care ; Drug Overdose/mortality ; Female ; Humans ; Thrombocytopenia/chemically induced ; Vomiting |
| مستخلص: | Background: Approximately ten times a year the Dutch National Poisons Information Centre (NVIC) is consulted regarding a colchicine intoxication or overdose. Case Description: An 18-year old woman was admitted to the intensive care unit after a suicide attempt with a potentially lethal dosage of colchicine tablets (0.5 mg/kg body weight). After a few hours the patient developed abdominal pain and vomited. Over subsequent days she developed anaemia, thrombocytopenia and a paralytic ileus. Treatment mainly comprised intensive supportive care, including sedation, ventilation and repeated administration of activated charcoal. After a week she gradually began to recover and was able to leave IC 10 days after ingestion. Conclusion: Early recognition and treatment of colchicine intoxication is crucial to preventing a fatal outcome. Complete recovery is possible if extensive supportive treatment is given. |
| المشرفين على المادة: | 16291-96-6 (Charcoal) SML2Y3J35T (Colchicine) |
| تواريخ الأحداث: | Date Created: 20150326 Date Completed: 20150824 Latest Revision: 20181202 |
| رمز التحديث: | 20221213 |
| PMID: | 25804106 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1876-8784 |
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