دورية أكاديمية
Uncomplicated malaria in children: The place of rapid diagnostic test.
| العنوان: | Uncomplicated malaria in children: The place of rapid diagnostic test. |
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| المؤلفون: | Elechi HA; Department of Paediatrics, University of Maiduguri, Maiduguri, Nigeria., Rabasa AI; Department of Paediatrics, Abubakar Tafawa Balewa University Teaching Hospital, Bauchi, Nigeria., Bashir MF; Department of Paediatrics, Abubakar Tafawa Balewa University Teaching Hospital, Bauchi, Nigeria., Gofama MM; Department of Paediatrics, University of Maiduguri, Maiduguri, Nigeria., Ibrahim HA; Department of Paediatrics, University of Maiduguri, Maiduguri, Nigeria., Askira UM; Deparetment of Medical Microbiology, University of Maiduguri, Maiduguri, Nigeria. |
| المصدر: | Nigerian medical journal : journal of the Nigeria Medical Association [Niger Med J] 2015 Mar-Apr; Vol. 56 (2), pp. 85-90. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Nigerian Medical Association Country of Publication: Nigeria NLM ID: 0315137 Publication Model: Print Cited Medium: Print ISSN: 0300-1652 (Print) Linking ISSN: 03001652 NLM ISO Abbreviation: Niger Med J Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Publication: 2021- : Abuja, Nigeria : Nigerian Medical Association Original Publication: Lagos : Literamed Publications (Nig.) Ltd. |
| مستخلص: | Background: Malaria has remained a major cause of morbidity and mortality among the under-five children in Nigeria. Prompt and accurate diagnosis of malaria is necessary in controlling this high burden and preventing unnecessary use of anti-malarial drugs. Malaria rapid diagnostic test (MRDT) offers the hope of achieving this goal. However, the performance of these kits among the most vulnerable age group to malaria is inadequate. Materials and Methods: In this cross-sectional study, 433 out-patients, aged <5 years with fever or history of fever were enrolled. Each candidate was tested for malaria parasitaemia using ACON; malaria pf. Thick and thin films were also prepared from the same finger prick blood for each candidate. Result: Malaria rapid diagnostic test had sensitivity of 8.3%, specificity of 100%, positive predictive value (PPV) of 100% and negative predictive value (NPV) of 74%. The sensitivity of MRDT increased with increasing age. This effect of age on sensitivity was statistically significant (P = 0.007). Similarly parasite density had significant effect on the sensitivity of MRDT (P = <0.001). Conclusion: Histidine-rich protein-2 based MRDT is not a reliable mean of diagnosing malaria in the under-five age children with acute uncomplicated malaria. |
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| فهرسة مساهمة: | Keywords: Febrile; malaria; malaria rapid diagnostic test; out-patient; under-five |
| تواريخ الأحداث: | Date Created: 20150404 Date Completed: 20150403 Latest Revision: 20181113 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC4382610 |
| DOI: | 10.4103/0300-1652.150686 |
| PMID: | 25838621 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0300-1652 |
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| DOI: | 10.4103/0300-1652.150686 |