دورية أكاديمية
Volaemic status and dyspepsia in end-stage renal disease patients.
| العنوان: | Volaemic status and dyspepsia in end-stage renal disease patients. |
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| المؤلفون: | Santos PR; School of Medicine, Sobral Campus, Federal University of Ceará, Sobral, Ceará, Brazil.; Dialysis Unit, Santa Casa Hospital, Sobral, Ceará, Brazil., Monteiro DL; School of Medicine, Sobral Campus, Federal University of Ceará, Sobral, Ceará, Brazil., de Paula PH; Dialysis Unit, Santa Casa Hospital, Sobral, Ceará, Brazil., Monte Neto VL; School of Medicine, Sobral Campus, Federal University of Ceará, Sobral, Ceará, Brazil., Coelho ML; Dialysis Unit, Santa Casa Hospital, Sobral, Ceará, Brazil., Arcanjo CC; School of Medicine, Sobral Campus, Federal University of Ceará, Sobral, Ceará, Brazil., Aragão SM; School of Medicine, Sobral Campus, Federal University of Ceará, Sobral, Ceará, Brazil., Gondim CB; School of Medicine, Sobral Campus, Federal University of Ceará, Sobral, Ceará, Brazil., Tapeti JT; School of Medicine, Sobral Campus, Federal University of Ceará, Sobral, Ceará, Brazil., Mendes HS; School of Medicine, Sobral Campus, Federal University of Ceará, Sobral, Ceará, Brazil., Vieira LV; School of Medicine, Sobral Campus, Federal University of Ceará, Sobral, Ceará, Brazil., Prado Rde C; School of Medicine, Sobral Campus, Federal University of Ceará, Sobral, Ceará, Brazil. |
| المصدر: | Nephrology (Carlton, Vic.) [Nephrology (Carlton)] 2015 Aug; Vol. 20 (8), pp. 519-22. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Blackwell Science Country of Publication: Australia NLM ID: 9615568 Publication Model: Print Cited Medium: Internet ISSN: 1440-1797 (Electronic) Linking ISSN: 13205358 NLM ISO Abbreviation: Nephrology (Carlton) Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Carlton, Vic., Australia : Blackwell Science, |
| مواضيع طبية MeSH: | Blood Volume*, Dyspepsia/*etiology , Kidney Failure, Chronic/*therapy , Renal Dialysis/*adverse effects, Adult ; Aged ; Blood Volume Determination ; Dyspepsia/diagnosis ; Dyspepsia/physiopathology ; Electric Impedance ; Female ; Gastrointestinal Motility ; Humans ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/diagnosis ; Kidney Failure, Chronic/physiopathology ; Linear Models ; Logistic Models ; Male ; Middle Aged ; Multivariate Analysis ; Odds Ratio ; Predictive Value of Tests ; Risk Factors ; Surveys and Questionnaires ; Treatment Outcome |
| مستخلص: | Aim: Studies in animals show a relationship between extracellular volume and gastrointestinal motility. End-stage renal disease (ESRD) patients present fluid overload and frequent dyspeptic symptoms. We looked for an association between volaemic status and dyspepsia among ESRD patients undergoing haemodialysis (HD). Methods: We studied 155 ESRD patients on HD. Their volaemic status was evaluated using bioimpedance analysis. Fluid overload (FO) in litres and relative fluid overload (rFO) in percentage were calculated. rFO > 15% was classified as hypervolaemia. Dyspepsia was assessed through the Porto Alegre Dyspeptic Symptoms Questionnaire (PADYQ). PADYQ scores equal to or greater than 6 classified patients as dyspeptic. Characteristics of patients with and without dyspepsia were compared. Pearson's test was used to test the correlation between continuous variables. Multivariate linear and logistic regressions were performed to test FO as predictor of dyspepsia score and the presence of dyspepsia. Results: There were 64 (41.2%) patients with dyspepsia. Dyspeptics presented higher FO (2.5 ± 1.8 L vs 1.0 ± 1.8 L; P < 0.001) and higher rFO (16 ± 9.9% vs 4.8 ± 12.0%; P < 0.001). Dyspepsia score was positively correlated with FO (r = 0.300; P < 0.001) and with rFO (r = 0.256; P = 0.001). There were more patients with hypervolaemia among dyspeptics compared to non-dyspeptics (65.6% vs 17.6%; P < 0.001). FO was an independent predictor of dyspepsia score (b = 1.036; P < 0.001) and the presence of dyspepsia (OR = 2.00, 95% CI = 1.55-2.50; P < 0.001). Conclusion: Hypervolaemia is associated with dyspepsia among ESRD patients on HD. (© 2015 Asian Pacific Society of Nephrology.) |
| فهرسة مساهمة: | Keywords: end-stage kidney disease; fluid and electrolyte disorders; gastrointestinal diseases; haemodialysis |
| تواريخ الأحداث: | Date Created: 20150410 Date Completed: 20160421 Latest Revision: 20150721 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1111/nep.12481 |
| PMID: | 25854288 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1440-1797 |
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| DOI: | 10.1111/nep.12481 |