دورية أكاديمية

Immunotherapy for hepatocellular carcinoma: From basic research to clinical use.

التفاصيل البيبلوغرافية
العنوان: Immunotherapy for hepatocellular carcinoma: From basic research to clinical use.
المؤلفون: Hong YP; Yu-Peng Hong, Department of Oncology, Zhejiang Provincial People's Hospital, Hangzhou 310014, Zhejiang Province, China., Li ZD; Yu-Peng Hong, Department of Oncology, Zhejiang Provincial People's Hospital, Hangzhou 310014, Zhejiang Province, China., Prasoon P; Yu-Peng Hong, Department of Oncology, Zhejiang Provincial People's Hospital, Hangzhou 310014, Zhejiang Province, China., Zhang Q; Yu-Peng Hong, Department of Oncology, Zhejiang Provincial People's Hospital, Hangzhou 310014, Zhejiang Province, China.
المصدر: World journal of hepatology [World J Hepatol] 2015 May 08; Vol. 7 (7), pp. 980-92.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Baishideng Publishing Group Country of Publication: United States NLM ID: 101532469 Publication Model: Print Cited Medium: Print ISSN: 1948-5182 (Print) NLM ISO Abbreviation: World J Hepatol Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: 2014- : Pleasanton, CA : Baishideng Publishing Group
Original Publication: Beijing, China : Baishideng
مستخلص: Hepatocellular carcinoma (HCC) is a common cancer worldwide with a poor prognosis. Few strategies have been proven efficient in HCC treatment, particularly for those patients not indicated for curative resection or transplantation. Immunotherapy has been developed for decades for cancer control and is attaining more attention as a result of encouraging outcomes of new strategies such as chimeric antigen receptor T cells and immune checkpoint blockade. Right at the front of the new era of immunotherapy, we review the immunotherapy in HCC treatment, from basic research to clinical trials, covering anything from immunomodulators, tumor vaccines and adoptive immunotherapy. The mechanisms, efficacy and safety as well as the approach particulars are unveiled to assist readers to gain a concise but extensive understanding of immunotherapy of HCC.
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فهرسة مساهمة: Keywords: Adoptive immunotherapy; Checkpoint blockade; Chemokine; Chimeric antigen receptor; Interferon; Tumor vaccine
تواريخ الأحداث: Date Created: 20150509 Date Completed: 20150508 Latest Revision: 20201001
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC4419101
DOI: 10.4254/wjh.v7.i7.980
PMID: 25954480
قاعدة البيانات: MEDLINE
الوصف
تدمد:1948-5182
DOI:10.4254/wjh.v7.i7.980