دورية أكاديمية
أعرض في EDS

Bone marrow-derived fibrocytes contribute to liver fibrosis.

التفاصيل البيبلوغرافية
العنوان: Bone marrow-derived fibrocytes contribute to liver fibrosis.
المؤلفون: Xu J; Department of Medicine, University of California, San Diego, CA 92093, USA., Kisseleva T; Department of Surgery, University of California, San Diego, CA 92093, USA tkisseleva@ucsd.edu.
المصدر: Experimental biology and medicine (Maywood, N.J.) [Exp Biol Med (Maywood)] 2015 Jun; Vol. 240 (6), pp. 691-700. Date of Electronic Publication: 2015 May 12.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Review
اللغة: English
بيانات الدورية: Publisher: Frontiers Media S.A Country of Publication: England NLM ID: 100973463 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-3699 (Electronic) Linking ISSN: 15353699 NLM ISO Abbreviation: Exp Biol Med (Maywood) Subsets: MEDLINE
أسماء مطبوعة: Publication: 2024- : Lausanne, Switzerland : Frontiers Media S.A.
Original Publication: Maywood, NJ : The Society, c2001-
مواضيع طبية MeSH: Bone Marrow Cells/*metabolism , Leukocyte Common Antigens/*metabolism , Liver Cirrhosis/*metabolism , Sepsis/*metabolism , Transforming Growth Factor beta1/*metabolism, Animals ; Bone Marrow Cells/pathology ; Collagen Type I/biosynthesis ; Humans ; Liver Cirrhosis/pathology ; Sepsis/pathology
مستخلص: Chronic liver injury often leads to hepatic fibrosis, a condition associated with increased levels of circulating TGF-β1 and lipopolysaccharide, activation of myofibroblasts, and extensive deposition of extracellular matrix, mostly collagen Type I. Hepatic stellate cells are considered to be the major(1) but not the only source of myofibroblasts in the injured liver.(2) Hepatic myofibroblasts may also originate from portal fibroblasts, mesenchymal cells, and fibrocytes.(3) Since the discovery of fibrocytes in 1994 by Dr. Bucala and colleagues, this bone marrow (BM)-derived collagen Type I-producing CD45(+) cells remain the most fascinating cells of the hematopoietic system. Due to the ability to differentiate into collagen Type I producing cells/myofibroblasts, fibrocytes were implicated in the pathogenesis of liver, skin, lung, and kidney fibrosis. However, studies of different organs often contain controversial results on the number of fibrocytes recruited to the site of injury and their biological function. Furthermore, fibrocytes were implicated in the pathogenesis of sepsis and were shown to possess antimicrobial activity. Finally, in response to specific stimuli, fibrocytes can give rise to fully differentiated macrophages, suggesting that in concurrence with the high plasticity of hematopoietic cells, fibrocytes exhibit progenitor properties. Here, we summarize our current understanding of the role of CD45(+)Collagen Type I(+) BM-derived cells in response to fibrogenic liver injury and septicemia and discuss the most recent evidence supporting the critical role of fibrocytes in the mediation of pro-fibrogenic and/or pro-inflammatory responses.
(© 2015 by the Society for Experimental Biology and Medicine.)
References: Am J Surg Pathol. 1998 Feb;22(2):141-7. (PMID: 9500214)
Nat Med. 2008 Sep;14(9):949-53. (PMID: 18690244)
J Biol Chem. 2001 Aug 24;276(34):31969-77. (PMID: 11423540)
Proteomics. 2010 Mar;10(5):1017-28. (PMID: 20049859)
J Leukoc Biol. 2005 Jun;77(6):923-33. (PMID: 15767291)
Nat Commun. 2013;4:2823. (PMID: 24264436)
Future Microbiol. 2008 Aug;3(4):437-51. (PMID: 18651815)
Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17892-7. (PMID: 19815530)
Stem Cells Dev. 2009 Jul-Aug;18(6):919-28. (PMID: 19021502)
Best Pract Res Clin Gastroenterol. 2011 Apr;25(2):207-17. (PMID: 21497739)
Int Immunol. 2000 Nov;12(11):1593-604. (PMID: 11058579)
J Am Soc Nephrol. 2008 Dec;19(12):2282-7. (PMID: 18987304)
J Clin Invest. 2004 Jan;113(2):243-52. (PMID: 14722616)
Nat Rev Microbiol. 2007 Aug;5(8):577-82. (PMID: 17632569)
J Clin Invest. 2004 Aug;114(3):438-46. (PMID: 15286810)
J Clin Invest. 2003 Nov;112(9):1383-94. (PMID: 14597764)
J Mol Med (Berl). 2011 Oct;89(10):997-1013. (PMID: 21499735)
Lancet. 1990 Sep 29;336(8718):763-5. (PMID: 1976144)
Gastroenterology. 2010 Sep;139(3):987-98. (PMID: 20546735)
Hepatology. 2009 Jul;50(1):185-97. (PMID: 19441102)
Mol Med. 1994 Nov;1(1):71-81. (PMID: 8790603)
Cell. 2008 Feb 22;132(4):612-30. (PMID: 18295579)
Keio J Med. 2005 Dec;54(4):190-2. (PMID: 16452829)
J Biol Chem. 2007 Aug 3;282(31):22910-20. (PMID: 17556364)
J Gastroenterol Hepatol. 2006 Oct;21 Suppl 3:S84-7. (PMID: 16958681)
Am J Pathol. 2011 Jul;179(1):189-98. (PMID: 21703401)
J Hepatol. 2011 Aug;55(2):459-65. (PMID: 21320559)
Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9448-53. (PMID: 22566629)
Immunity. 2007 Jan;26(1):117-29. (PMID: 17239632)
J Am Coll Radiol. 2008 Jan;5(1):36-9. (PMID: 18180007)
J Immunol. 2003 Nov 15;171(10):5537-46. (PMID: 14607961)
J Cell Biol. 2004 Jun 7;165(5):723-34. (PMID: 15184403)
J Clin Invest. 2009 Jul;119(7):1858-70. (PMID: 19603542)
Hepatology. 2009 Dec;50(6):2007-13. (PMID: 19824076)
Curr Opin Rheumatol. 2006 Nov;18(6):614-7. (PMID: 17053507)
J Hepatol. 2012 Oct;57(4):860-6. (PMID: 22668639)
Cell Mol Life Sci. 2005 Nov;62(22):2549-59. (PMID: 16261255)
Hepatology. 2002 Nov;36(5):1135-44. (PMID: 12395323)
J Clin Invest. 2007 Mar;117(3):549-56. (PMID: 17332882)
Experientia. 1971 May 15;27(5):549-50. (PMID: 5132594)
Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):14098-103. (PMID: 16966615)
Lab Invest. 1997 Jun;76(6):765-78. (PMID: 9194853)
Cell Cycle. 2013 Feb 1;12(3):381-2. (PMID: 23324345)
Mol Aspects Med. 2008 Feb-Apr;29(1-2):58-66. (PMID: 18022682)
Curr Opin Immunol. 2006 Aug;18(4):512-6. (PMID: 16777399)
Lab Invest. 2007 Sep;87(9):858-70. (PMID: 17607298)
J Immunol. 2007 Apr 15;178(8):5288-95. (PMID: 17404313)
Hepatol Res. 2011 Jul;41(7):683-6. (PMID: 21711427)
Hepatology. 2010 Jan;51(1):267-76. (PMID: 19827165)
Hepatology. 1992 Dec;16(6):1452-73. (PMID: 1446899)
Science. 2004 Mar 5;303(5663):1532-5. (PMID: 15001782)
J Cell Mol Med. 2008 Jan-Feb;12(1):22-37. (PMID: 18182061)
J Cell Biol. 2007 Jun 18;177(6):1119-32. (PMID: 17576803)
Nat Protoc. 2012 Mar 29;7(4):771-81. (PMID: 22461066)
J Leukoc Biol. 2007 Sep;82(3):449-56. (PMID: 17550974)
Am J Pathol. 2005 Mar;166(3):675-84. (PMID: 15743780)
J Leukoc Biol. 2007 Sep;82(3):710-20. (PMID: 17595377)
Lab Invest. 2003 Feb;83(2):163-73. (PMID: 12594232)
J Clin Invest. 2005 Feb;115(2):209-18. (PMID: 15690074)
J Vis Exp. 2012 Jun 29;(64):. (PMID: 22781701)
Hepatology. 2011 May;53(5):1685-95. (PMID: 21520179)
J Gastroenterol Hepatol. 2012 Mar;27 Suppl 2:94-8. (PMID: 22320925)
Nat Rev Mol Cell Biol. 2002 Feb;3(2):122-31. (PMID: 11836514)
J Hepatol. 2012 Apr;56(4):965-72. (PMID: 22173163)
Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):308-13. (PMID: 21173249)
Lab Invest. 2002 May;82(5):619-28. (PMID: 12004002)
Nat Med. 2007 Aug;13(8):952-61. (PMID: 17660828)
Crit Rev Immunol. 2008;28(3):185-200. (PMID: 19024344)
J Histochem Cytochem. 2008 Apr;56(4):347-58. (PMID: 18071065)
Exp Dermatol. 2006 Oct;15(10):808-14. (PMID: 16984263)
Nat Med. 2007 Nov;13(11):1324-32. (PMID: 17952090)
Proc Natl Acad Sci U S A. 1985 Dec;82(24):8681-5. (PMID: 3909149)
Gastroenterology. 2012 Oct;143(4):1073-83.e22. (PMID: 22750464)
Best Pract Res Clin Gastroenterol. 2011 Apr;25(2):305-17. (PMID: 21497747)
J Leukoc Biol. 2009 Nov;86(5):1111-8. (PMID: 19581373)
J Invest Dermatol. 2008 Aug;128(8):1915-9. (PMID: 18305566)
J Immunol Methods. 2010 Dec 15;363(1):9-20. (PMID: 20888336)
J Hepatol. 2006 Sep;45(3):429-38. (PMID: 16846660)
J Clin Invest. 2003 Dec;112(12):1776-84. (PMID: 14679171)
J Immunol. 2001 Jun 15;166(12):7556-62. (PMID: 11390511)
Int J Biochem Cell Biol. 2004 Apr;36(4):598-606. (PMID: 15010326)
Am J Respir Crit Care Med. 2009 Apr 1;179(7):588-94. (PMID: 19151190)
J Clin Invest. 2005 Jan;115(1):56-65. (PMID: 15630444)
Lab Invest. 2006 Mar;86(3):275-85. (PMID: 16402030)
J Immunol. 2008 Apr 15;180(8):5707-19. (PMID: 18390756)
Vitam Horm. 2007;75:131-59. (PMID: 17368315)
J Gastroenterol Hepatol. 2012 Mar;27 Suppl 2:65-8. (PMID: 22320919)
Methods Mol Biol. 2008;447:33-48. (PMID: 18369909)
Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):E3297-305. (PMID: 25074909)
Biochem Pharmacol. 2006 Nov 30;72(11):1622-31. (PMID: 16846592)
Semin Liver Dis. 2001 Aug;21(3):311-35. (PMID: 11586463)
Int J Biochem Cell Biol. 2006 Feb;38(2):135-51. (PMID: 16257564)
J Immunol. 1993 Dec 15;151(12):6742-50. (PMID: 7903097)
J Hypertens. 2008 Apr;26(4):780-90. (PMID: 18327089)
Blood. 2008 Mar 15;111(6):3070-80. (PMID: 18182576)
Biochem Soc Trans. 1997 May;25(2):520-4. (PMID: 9191147)
Am J Respir Cell Mol Biol. 2006 Aug;35(2):175-81. (PMID: 16543609)
Sci Signal. 2008 May 27;1(21):pe25. (PMID: 18506034)
J Immunol. 2008 May 15;180(10):6846-53. (PMID: 18453605)
Am J Pathol. 2007 Mar;170(3):843-54. (PMID: 17322370)
Lab Invest. 1996 Jan;74(1):265-78. (PMID: 8569191)
Nature. 2001 Nov 22;414(6862):454-7. (PMID: 11719807)
Exp Biol Med (Maywood). 2008 Feb;233(2):109-22. (PMID: 18222966)
J Immunol. 2007 Sep 15;179(6):4035-44. (PMID: 17785842)
J Mol Med (Berl). 2009 Aug;87(8):775-83. (PMID: 19444424)
PLoS One. 2010 Mar 18;5(3):e9730. (PMID: 20305780)
J Investig Med. 2002 May;50(3):179-84. (PMID: 12033282)
J Clin Invest. 2007 Mar;117(3):539-48. (PMID: 17332881)
Proc Am Thorac Soc. 2008 Apr 15;5(3):338-42. (PMID: 18403330)
Hepatology. 2010 Apr;51(4):1438-44. (PMID: 20209607)
Science. 1971 Aug 6;173(3996):548-50. (PMID: 4327529)
Am J Pathol. 2008 Dec;173(6):1617-27. (PMID: 19008372)
J Clin Invest. 2009 Jun;119(6):1417-9. (PMID: 19487817)
Gastroenterology. 1999 Nov;117(5):1205-21. (PMID: 10535885)
Hepatology. 2009 Mar;49(3):901-10. (PMID: 19072833)
Nat Med. 2012 Jul 06;18(7):1028-40. (PMID: 22772564)
Nat Rev Immunol. 2006 Dec;6(12):940-52. (PMID: 17124515)
Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6307-12. (PMID: 9177213)
معلومات مُعتمدة: R01 DK099205-01A1 United States DK NIDDK NIH HHS; R01 DK099205 United States DK NIDDK NIH HHS; R01 DK101737-01A1 United States DK NIDDK NIH HHS; U01 AA022614 United States AA NIAAA NIH HHS; R01 DK101737 United States DK NIDDK NIH HHS; R56 DK088837 United States DK NIDDK NIH HHS; U01 AA022614-01A1 United States AA NIAAA NIH HHS
فهرسة مساهمة: Keywords: Fibrocytes; bone marrow; collagen type I; liver fibrosis; myeloid cells; myofibroblasts
المشرفين على المادة: 0 (Collagen Type I)
0 (TGFB1 protein, human)
0 (Transforming Growth Factor beta1)
EC 3.1.3.48 (Leukocyte Common Antigens)
EC 3.1.3.48 (PTPRC protein, human)
تواريخ الأحداث: Date Created: 20150514 Date Completed: 20150821 Latest Revision: 20200306
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC4866973
DOI: 10.1177/1535370215584933
PMID: 25966982
قاعدة البيانات: MEDLINE
الوصف
تدمد:1535-3699
DOI:10.1177/1535370215584933