دورية أكاديمية

[Analysis of diversity and identification of the genovariants of plague agent strains from Mongolian foci].

التفاصيل البيبلوغرافية
العنوان: [Analysis of diversity and identification of the genovariants of plague agent strains from Mongolian foci].
المؤلفون: Kukleva LM, Shavina NY, Odinokov GN, Oglodin EG, Nosov NY, Vinogradova NA, Guseva NP, Eroshenko GA, Kutyrev VV
المصدر: Genetika [Genetika] 2015 Mar; Vol. 51 (3), pp. 298-305.
نوع المنشور: Journal Article
اللغة: Russian
بيانات الدورية: Publisher: Izdatelstvo Nauka Country of Publication: Russia (Federation) NLM ID: 0047354 Publication Model: Print Cited Medium: Print ISSN: 0016-6758 (Print) Linking ISSN: 00166758 NLM ISO Abbreviation: Genetika Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Moskva : Izdatelstvo Nauka
مواضيع طبية MeSH: Genetic Variation* , Phylogeny*, Yersinia pestis/*classification , Yersinia pestis/*genetics, Mongolia ; Plague/classification ; Plague/genetics
مستخلص: The genetic diversity of Yersinia pestis strains from the Mongolian natural plague foci has been investigated. A total of 32 strains isolated from western, eastern, and central aimaks, as well as from the territory of the Gobi region, have been studied. Twenty-four strains belong to the main Y. pestis subspecies, while eight belong to other subspecies. There is only one strain of biovar medievalis (genovariant 2.MED1) among the strains of the main subspecies, while the rest of the subspecies belong to the biovar antiqua. Biovar antiqua strains are split into three groups. Strains from the eastern part of the country were classified as genovariant 2.ANT3, and those from the western and central regions were classified as genovariant 3.ANT2, which was endemic for Mongolia. One strain from the Bayan-Ulegeiskii aimak had the rare genovariant 4.ANT. None of the strains of the biovar antiqua belonged to its ancient 0.ANT branch, which is inconsistent with the commonly accepted idea that ancient marmot's plague agent race originates from Mongolia. Six out of eight strains of the minor subspecies belonged to the ulegeica subspecies, which are endemic to Mongolia, one strain belonged to the microtus group, and the last belonged to a previously uncharacterized variant of the minor subspecies.
تواريخ الأحداث: Date Created: 20150602 Date Completed: 20150612 Latest Revision: 20201209
رمز التحديث: 20231215
PMID: 26027368
قاعدة البيانات: MEDLINE