دورية أكاديمية
Clindamycin Resistance among Staphylococcus Aureus Isolated at Mbarara Regional Referral Hospital, in South Western Uganda.
| العنوان: | Clindamycin Resistance among Staphylococcus Aureus Isolated at Mbarara Regional Referral Hospital, in South Western Uganda. |
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| المؤلفون: | Mwambi B; Department of Microbiology, Mbarara University of Science and Technology, P.O.Box 1410 Mbarara, Uganda., Iramiot J; Department of Microbiology, Mbarara University of Science and Technology, P.O.Box 1410 Mbarara, Uganda., Bwanga F; Department of Medical Microbiology Makerere University College of Health Sciences P. O Box 7072 Kampala, Uganda. ; MBN Clinical Laboratories, Uganda., Nakaye M; Department of Microbiology, Mbarara University of Science and Technology, P.O.Box 1410 Mbarara, Uganda., Itabangi H; Department of Microbiology, Mbarara University of Science and Technology, P.O.Box 1410 Mbarara, Uganda., Bazira J; Department of Microbiology, Mbarara University of Science and Technology, P.O.Box 1410 Mbarara, Uganda. |
| المصدر: | British microbiology research journal [Br Microbiol Res J] 2014 Dec 01; Vol. 4 (12), pp. 1335-1344. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Sciencedomain International Country of Publication: India NLM ID: 101608140 Publication Model: Print Cited Medium: Print ISSN: 2231-0886 (Print) Linking ISSN: 22310886 NLM ISO Abbreviation: Br Microbiol Res J Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Gurgaon : Sciencedomain International |
| مستخلص: | Aims: The study was conducted to determine the prevalence of Clindamycin (CL) resistance and antimicrobial susceptibility among clinical isolates of Staphylococcus aureus ( S. aureus ) from Mbarara Regional Referral Hospital (MRRH) in Southwestern Uganda. Study Design: Laboratory based cross sectional study. Place and Duration of the Study: The study was conducted at the Microbiology department of Mbarara Regional referral hospital between November 2012 and December 2013. Methodology: In our study, we recruited 300 S. aureus isolates that were stored in the laboratory and were obtained from different clinical samples. The isolates were tested for antimicrobial susceptibility by phenotypic methods and for the genotypic expression of Macrolide Lincosamide StreptograminB (MLS Results: Phenotypically, a total of 109 (36%) S. aureus isolates were resistant to CL, of which 9 (3%) were constitutively resistant while 100 (33.3%) were inducibly resistant. Genotypicaly, 134/300 (44.7%) isolates possessed at least one of the MLS Conclusion: S. aureus resistance to CL was high in this set up. There was also high resistance to Sulfamethoxazole/trimethoprim, Erythromycin and Oxacillin but low resistance to Linezolid. |
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| معلومات مُعتمدة: | R24 TW008886 United States TW FIC NIH HHS |
| فهرسة مساهمة: | Keywords: Staphylococcus aureus; clindamycin; d-test; genetic; phenotypic; resistance |
| تواريخ الأحداث: | Date Created: 20150606 Latest Revision: 20220321 |
| رمز التحديث: | 20221213 |
| مُعرف محوري في PubMed: | PMC4451190 |
| DOI: | 10.9734/BMRJ/2014/10572 |
| PMID: | 26046016 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 2231-0886 |
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| DOI: | 10.9734/BMRJ/2014/10572 |