دورية أكاديمية
The NLRP3 inflammasome and stroke.
| العنوان: | The NLRP3 inflammasome and stroke. |
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| المؤلفون: | Tong Y; Hubei Center for Disease Control and Prevention Wuhan 430079, P. R. China ; School of Public Health, Tongji Medical College, Huazhong University of Science and Technology Wuhan 430030, P. R China., Ding ZH; Xiangyang Hospital of Traditional Chinese Medical Hospital Xiangyang 441021, P. R. China., Zhan FX; Hubei Center for Disease Control and Prevention Wuhan 430079, P. R. China., Cai L; Wuhan Center for Disease Control and Prevention Wuhan, 430015, P. R. China., Yin X; School of Public Health, Tongji Medical College, Huazhong University of Science and Technology Wuhan 430030, P. R China., Ling JL; Queens University Belfast Northern Ireland, United Kingdom., Ye JJ; Hubei Center for Disease Control and Prevention Wuhan 430079, P. R. China., Hou SY; Hubei Center for Disease Control and Prevention Wuhan 430079, P. R. China., Lu Z; School of Public Health, Tongji Medical College, Huazhong University of Science and Technology Wuhan 430030, P. R China., Wang ZH; Department of Neurology, Shenzhen NO. 2 People's Hospital, The First Affiliated Hospital of Shenzhen University Shenzhen 518035, P. R. China., Liu JF; Hubei Center for Disease Control and Prevention Wuhan 430079, P. R. China. |
| المصدر: | International journal of clinical and experimental medicine [Int J Clin Exp Med] 2015 Apr 15; Vol. 8 (4), pp. 4787-94. Date of Electronic Publication: 2015 Apr 15 (Print Publication: 2015). |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: e-Century Pub. Corp Country of Publication: United States NLM ID: 101471010 Publication Model: eCollection Cited Medium: Print ISSN: 1940-5901 (Print) Linking ISSN: 19405901 NLM ISO Abbreviation: Int J Clin Exp Med Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Madison, WI : e-Century Pub. Corp. |
| مستخلص: | Inflammasome pattern recognition receptors, which belong to the family of multi-meric proteins, play an important role in innate immunity, including NLRPs, NLRC, and NAIP. Among these receptors, NLRP3 (nucleotide-binding domain (NOD)-like receptor protein 3) inflammasome may activate the inflammation and participate in atherosclerosis, pathophysiology of myocardial infarction, resultin ischemia/reperfusion injury and stroke and other cardiovascular diseases. Effective regulation of NLRP3 may help prevent or even treat stroke. In recent years, the role of inflammation in stroke has attracted much attention, and the in-depth study of its mechanism of action is gradually clear. This mini-review focuses on the association of regulatory mechanisms of NLRP3 inflammasome with the development of stroke, which may supply some clues for future therapies and novel drug targets for stroke. |
| References: | Curr Top Med Chem. 2009;9(14):1240-60. (PMID: 19849665) Inflammation. 2014 Apr;37(2):457-66. (PMID: 24158569) J Cell Biol. 2001 Aug 6;154(3):485-90. (PMID: 11489912) Stroke. 2004 Nov;35(11 Suppl 1):2712-9. (PMID: 15472106) Arterioscler Thromb Vasc Biol. 2004 Dec;24(12):2313-9. (PMID: 15472128) Lancet Neurol. 2004 Apr;3(4):227-35. (PMID: 15039035) Circulation. 1995 May 1;91(9):2488-96. (PMID: 7729036) Med Clin (Barc). 2011 Jan;136 Suppl 1:34-7. (PMID: 21596185) Cell Death Dis. 2013 Sep 05;4:e790. (PMID: 24008734) J Vasc Interv Neurol. 2014 May;7(1):11-20. (PMID: 24920983) Circulation. 2011 Feb 15;123(6):594-604. (PMID: 21282498) Expert Opin Investig Drugs. 2011 Jul;20(7):897-915. (PMID: 21510825) N Engl J Med. 2013 Jul 4;369(1):11-9. (PMID: 23803136) Proc Natl Acad Sci U S A. 2007 May 8;104(19):8041-6. (PMID: 17483456) Clin Sci (Lond). 2014 Feb;126(3):233-41. (PMID: 23944632) Lancet. 2011 May 14;377(9778):1681-92. (PMID: 21571151) Expert Opin Investig Drugs. 2012 Jul;21(7):995-1007. (PMID: 22612568) PLoS One. 2011;6(12 ):e29539. (PMID: 22216309) Sci Rep. 2014 Jun 03;4:5149. (PMID: 24889025) J Invest Dermatol. 2014 Feb;134(2):381-8. (PMID: 23884315) Br J Pharmacol. 2006 Dec;149(7):880-7. (PMID: 17031385) Stroke. 2007 May;38(5):1655-711. (PMID: 17431204) Science. 2010 Oct 15;330(6002):362-6. (PMID: 20947763) Public Health. 2012 Mar;126(3):210-3. (PMID: 22325671) Clin Exp Immunol. 2011 Oct;166(1):1-15. (PMID: 21762124) Int J Mol Med. 2014 Jul;34(1):341-9. (PMID: 24789624) Drug News Perspect. 2007 May;20(4):221-6. (PMID: 17637934) Nat Immunol. 2010 Feb;11(2):136-40. (PMID: 20023662) Harefuah. 2005 Sep;144(9):647-54, 675. (PMID: 16218538) PLoS One. 2013 Oct 28;8(10 ):e77794. (PMID: 24204969) Atherosclerosis. 2000 Jan;148(1):23-30. (PMID: 10580167) PLoS One. 2013 Apr 29;8(4):e62426. (PMID: 23658628) Neurology. 1998 Jan;50(1):196-203. (PMID: 9443480) Ann Rheum Dis. 2007 Dec;66(12):1683-4. (PMID: 17998217) EMBO J. 2009 Jul 22;28(14 ):2114-27. (PMID: 19536133) Lancet. 2014 Jan 18;383(9913):245-54. (PMID: 24449944) Arterioscler Thromb Vasc Biol. 2014 Mar;34(3):499-508. (PMID: 24526695) Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20388-93. (PMID: 19918053) Cell. 2010 Mar 19;140(6):821-32. (PMID: 20303873) J Immunol. 2014 May 1;192(9):4342-51. (PMID: 24696236) Lancet. 2012 Dec 15;380(9859):2095-128. (PMID: 23245604) Lancet Neurol. 2007 Feb;6(2):149-61. (PMID: 17239802) Cerebrovasc Dis. 2005;20 Suppl 2:75-83. (PMID: 16327256) Curr Pharm Des. 2012;18(28):4266-88. (PMID: 22390643) Antimicrob Agents Chemother. 2012 Apr;56(4):1921-30. (PMID: 22290938) PLoS One. 2012;7(7):e40643. (PMID: 22848390) Neurology. 2012 Feb 28;78(9):683-4. (PMID: 22371416) Stroke. 1996 Nov;27(11):1999-2004. (PMID: 8898805) Mol Cell. 2002 Aug;10(2):417-26. (PMID: 12191486) Lancet. 2014 Mar 15;383(9921):970-83. (PMID: 24269108) Am Heart J. 2011 Oct;162(4):597-605. (PMID: 21982649) Am J Respir Crit Care Med. 2012 Mar 1;185(5):547-56. (PMID: 22246178) Nature. 2010 Apr 29;464(7293):1357-61. (PMID: 20428172) Immunity. 2008 Mar;28(3):285-7. (PMID: 18341998) Circulation. 2012 Dec 4;126(23 ):2739-48. (PMID: 23129601) Crit Rev Biochem Mol Biol. 2012 Sep;47(5):424-43. (PMID: 22681257) PLoS Pathog. 2014 Jan;10 (1):e1003885. (PMID: 24453977) PLoS One. 2012;7(1):e29695. (PMID: 22295065) Am J Cardiovasc Dis. 2011;1(3):244-54. (PMID: 22254202) Exp Physiol. 2013 Feb;98 (2):462-72. (PMID: 22848083) Stroke Res Treat. 2011;2011:179061. (PMID: 21912753) Heart Lung Circ. 2013 Sep;22(9):746-50. (PMID: 23462287) J Immunol. 2014 Feb 15;192(4):1835-46. (PMID: 24453255) J Cereb Blood Flow Metab. 2014 Apr;34(4):660-7. (PMID: 24424382) Stroke. 1996 Dec;27(12):2204-6. (PMID: 8969781) Lancet. 2008 May 10;371(9624):1612-23. (PMID: 18468545) Cell. 2012 May 11;149(4):847-59. (PMID: 22541070) Open Rheumatol J. 2012;6:80-6. (PMID: 22802905) |
| فهرسة مساهمة: | Keywords: NLRP3; inflammasome; inflammation; stroke |
| تواريخ الأحداث: | Date Created: 20150702 Date Completed: 20150701 Latest Revision: 20201001 |
| رمز التحديث: | 20221213 |
| مُعرف محوري في PubMed: | PMC4483817 |
| PMID: | 26131053 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1940-5901 |
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