دورية أكاديمية
Cold water cleaning of brain proteins, biofilm and bone - harnessing an ultrasonically activated stream.
| العنوان: | Cold water cleaning of brain proteins, biofilm and bone - harnessing an ultrasonically activated stream. |
|---|---|
| المؤلفون: | Birkin PR; Chemistry, University of Southampton, SO17 1BJ, UK. prb2@soton.ac.uk., Offin DG, Vian CJ, Howlin RP, Dawson JI, Secker TJ, Hervé RC, Stoodley P, Oreffo RO, Keevil CW, Leighton TG |
| المصدر: | Physical chemistry chemical physics : PCCP [Phys Chem Chem Phys] 2015 Aug 28; Vol. 17 (32), pp. 20574-9. Date of Electronic Publication: 2015 Jul 22. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 100888160 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-9084 (Electronic) Linking ISSN: 14639076 NLM ISO Abbreviation: Phys Chem Chem Phys Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Cambridge [England] : Royal Society of Chemistry, c1999- |
| مواضيع طبية MeSH: | Biofilms* , Ultrasonics*, Brain/*metabolism , Proteins/*metabolism , Staphylococcus epidermidis/*metabolism , Water/*metabolism, Animals ; Mice ; Mice, Inbred C57BL ; Proteins/chemistry ; Stainless Steel/chemistry ; Temperature ; Water/chemistry |
| مستخلص: | In the absence of sufficient cleaning of medical instruments, contamination and infection can result in serious consequences for the health sector and remains a significant unmet challenge. In this paper we describe a novel cleaning system reliant on cavitation action created in a free flowing fluid stream where ultrasonic transmission to a surface, through the stream, is achieved using careful design and control of the device architecture, sound field and the materials employed. Cleaning was achieved with purified water at room temperature, moderate fluid flow rates and without the need for chemical additives or the high power consumption associated with conventional strategies. This study illustrates the potential in harnessing an ultrasonically activated stream to remove biological contamination including brain tissue from surgical stainless steel substrates, S. epidermidis biofilms from glass, and fat/soft tissue matter from bone structures with considerable basic and clinical applications. |
| المشرفين على المادة: | 0 (Proteins) 059QF0KO0R (Water) 12597-68-1 (Stainless Steel) |
| تواريخ الأحداث: | Date Created: 20150723 Date Completed: 20160121 Latest Revision: 20150806 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1039/c5cp02406d |
| PMID: | 26200694 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1463-9084 |
|---|---|
| DOI: | 10.1039/c5cp02406d |