دورية أكاديمية
Efficacy of humidity retention bags for the reduced adsorption and improved cleaning of tissue proteins including prion-associated amyloid to surgical stainless steel surfaces.
| العنوان: | Efficacy of humidity retention bags for the reduced adsorption and improved cleaning of tissue proteins including prion-associated amyloid to surgical stainless steel surfaces. |
|---|---|
| المؤلفون: | Secker TJ; a Environmental Healthcare Unit, Centre for Biological Sciences , University of Southampton , Southampton , UK., Pinchin HE, Hervé RC, Keevil CW |
| المصدر: | Biofouling [Biofouling] 2015; Vol. 31 (6), pp. 535-41. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Taylor & Francis Country of Publication: England NLM ID: 9200331 Publication Model: Print Cited Medium: Internet ISSN: 1029-2454 (Electronic) Linking ISSN: 08927014 NLM ISO Abbreviation: Biofouling Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2002- : Abingdon, Oxford : Taylor & Francis Original Publication: Chur ; New York : Harwood Academic Publishers, c1988- |
| مواضيع طبية MeSH: | Humidity*, Amyloid/*analysis , Decontamination/*methods , Equipment Contamination/*prevention & control , Prions/*analysis , Stainless Steel/*chemistry , Surgical Instruments/*standards, Adsorption ; Biofouling ; Cross Infection/prevention & control ; Desiccation ; Humans ; Staining and Labeling |
| مستخلص: | Increasing drying time adversely affects attachment of tissue proteins and prion-associated amyloid to surgical stainless steel, and reduces the efficacy of commercial cleaning chemistries. This study tested the efficacy of commercial humidity retention bags to reduce biofouling on surgical stainless steel and to improve subsequent cleaning. Surgical stainless steel surfaces were contaminated with ME7-infected brain homogenates and left to dry for 15 to 1,440 min either in air, in dry polythene bags or within humidity retention bags. Residual contamination pre/post cleaning was analysed using Thioflavin T/SYPRO Ruby dual staining and microscope analysis. An increase in biofouling was observed with increased drying time in air or in sealed dry bags. Humidity retention bags kept both protein and prion-associated amyloid minimal across the drying times both pre- and post-cleaning. Therefore, humidity bags demonstrate a cheap, easy to implement solution to improve surgical instrument reprocessing and to potentially reduce associated hospital acquired infections. |
| معلومات مُعتمدة: | United Kingdom Department of Health |
| فهرسة مساهمة: | Keywords: contamination; decontamination; hospital infections; humidity; prions; proteins |
| المشرفين على المادة: | 0 (Amyloid) 0 (Prions) 12597-68-1 (Stainless Steel) |
| تواريخ الأحداث: | Date Created: 20150813 Date Completed: 20160208 Latest Revision: 20181202 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1080/08927014.2015.1067686 |
| PMID: | 26263927 |
| قاعدة البيانات: | MEDLINE |
PDF full text from Publisher 
Full Text Finder | تدمد: | 1029-2454 |
|---|---|
| DOI: | 10.1080/08927014.2015.1067686 |