دورية أكاديمية

The adaptive evolution of virulence: a review of theoretical predictions and empirical tests.

التفاصيل البيبلوغرافية
العنوان: The adaptive evolution of virulence: a review of theoretical predictions and empirical tests.
المؤلفون: Cressler CE; Department of Mathematics & Statistics, Queen's University, Kingston, ON K7L 3N6, Canada.; Department of Biology, Queen's University, Kingston, ON K7L 3N6, Canada., McLEOD DV; Department of Mathematics & Statistics, Queen's University, Kingston, ON K7L 3N6, Canada., Rozins C; Department of Mathematics & Statistics, Queen's University, Kingston, ON K7L 3N6, Canada., VAN DEN Hoogen J; Department of Mathematics & Statistics, Queen's University, Kingston, ON K7L 3N6, Canada., Day T; Department of Mathematics & Statistics, Queen's University, Kingston, ON K7L 3N6, Canada.; Department of Biology, Queen's University, Kingston, ON K7L 3N6, Canada.; Fogarty International Center, National Institutes of Health, Bethesda, Maryland 20892, USA.
المصدر: Parasitology [Parasitology] 2016 Jun; Vol. 143 (7), pp. 915-930. Date of Electronic Publication: 2015 Aug 25.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Cambridge University Press Country of Publication: England NLM ID: 0401121 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-8161 (Electronic) Linking ISSN: 00311820 NLM ISO Abbreviation: Parasitology Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London, New York, Cambridge University Press.
مواضيع طبية MeSH: Biological Evolution* , Host-Parasite Interactions* , Models, Biological* , Virulence*, Parasites/*pathogenicity, Animals ; Humans
مستخلص: Why is it that some parasites cause high levels of host damage (i.e. virulence) whereas others are relatively benign? There are now numerous reviews of virulence evolution in the literature but it is nevertheless still difficult to find a comprehensive treatment of the theory and data on the subject that is easily accessible to non-specialists. Here we attempt to do so by distilling the vast theoretical literature on the topic into a set of relatively few robust predictions. We then provide a comprehensive assessment of the available empirical literature that tests these predictions. Our results show that there have been some notable successes in integrating theory and data but also that theory and empiricism in this field do not 'speak' to each other very well. We offer a few suggestions for how the connection between the two might be improved.
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فهرسة مساهمة: Keywords: Tradeoff hypothesis; evolutionary medicine; infectious disease
تواريخ الأحداث: Date Created: 20150826 Date Completed: 20170317 Latest Revision: 20210109
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC4873896
DOI: 10.1017/S003118201500092X
PMID: 26302775
قاعدة البيانات: MEDLINE
الوصف
تدمد:1469-8161
DOI:10.1017/S003118201500092X