دورية أكاديمية
أعرض في EDS

Transarterial Embolization for Hepatocellular Carcinoma: A Comparison between Nonspherical PVA and Microspheres.

التفاصيل البيبلوغرافية
العنوان: Transarterial Embolization for Hepatocellular Carcinoma: A Comparison between Nonspherical PVA and Microspheres.
المؤلفون: Scaffaro LA; Radiology Division, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil., Kruel CD; Surgery Division, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil., Stella SF; Institute for Health Technology Assessment, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil., Gravina GL; School of Medicine, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil., Machado Filho G; School of Medicine, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil., Borges de Almeida CP; School of Medicine, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil., Pinto LC; School of Medicine, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil., Alvares-da-Silva MR; Gastroenterology Division, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil., Kruel CR; Surgery Division, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.
المصدر: BioMed research international [Biomed Res Int] 2015; Vol. 2015, pp. 435120. Date of Electronic Publication: 2015 Aug 27.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Hindawi Pub. Co Country of Publication: United States NLM ID: 101600173 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2314-6141 (Electronic) NLM ISO Abbreviation: Biomed Res Int Subsets: MEDLINE
أسماء مطبوعة: Original Publication: New York, NY : Hindawi Pub. Co.
مواضيع طبية MeSH: Microspheres*, Carcinoma, Hepatocellular/*therapy , Chemoembolization, Therapeutic/*methods , Liver Neoplasms/*therapy , Polyvinyl Alcohol/*therapeutic use, Aged ; Female ; Humans ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Retrospective Studies
مستخلص: Transarterial chemoembolization (TACE) and transarterial embolization (TAE) have improved the survival rates of patients with unresectable hepatocellular carcinoma (HCC); however, the optimal TACE/TAE embolic agent has not yet been identified. The aim of this study was to compare the effect of two different embolic agents such as microspheres (ME) and polyvinyl alcohol (PVA) on survival, tumor response, and complications in patients with HCC submitted to transarterial embolization (TAE). Eighty HCC patients who underwent TAE between June 2008 and December 2012 at a single center were retrospectively studied. A total of 48 and 32 patients were treated with PVA and ME, respectively. There were no significant differences in survival (P = 0.679) or tumoral response (P = 0.369) between groups (PVA or ME). Overall survival rates at 12, 18, 24, 36, and 48 months were 97.9, 88.8, 78.9, 53.4, and 21.4% in the PVA-TAE group and 100, 92.9, 76.6, 58.8, and 58% in the ME-TAE group (P = 0.734). Patients submitted to TAE with ME presented postembolization syndrome more frequently when compared with the PVA group (P = 0.02). According to our cohort, the choice of ME or PVA as embolizing agent had no significant impact on overall survival.
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المشرفين على المادة: 9002-89-5 (Polyvinyl Alcohol)
تواريخ الأحداث: Date Created: 20150929 Date Completed: 20160725 Latest Revision: 20181113
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC4564629
DOI: 10.1155/2015/435120
PMID: 26413523
قاعدة البيانات: MEDLINE
الوصف
تدمد:2314-6141
DOI:10.1155/2015/435120