دورية أكاديمية
HBV carriage in children born from HIV-seropositive mothers in Senegal: The need of birth-dose HBV vaccination.
العنوان: | HBV carriage in children born from HIV-seropositive mothers in Senegal: The need of birth-dose HBV vaccination. |
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المؤلفون: | Gueye SB; Laboratoire Bactériologie-Virologie, CHU Le Dantec, Université Cheikh Anta Diop, Dakar-Sénégal, Dakar, Senegal., Diop-Ndiaye H; Laboratoire Bactériologie-Virologie, CHU Le Dantec, Université Cheikh Anta Diop, Dakar-Sénégal, Dakar, Senegal., Lo G; Laboratoire Bactériologie-Virologie, CHU Le Dantec, Université Cheikh Anta Diop, Dakar-Sénégal, Dakar, Senegal., Mintsa S; Laboratoire Bactériologie-Virologie, CHU Le Dantec, Université Cheikh Anta Diop, Dakar-Sénégal, Dakar, Senegal., Guindo I; Laboratoire Bactériologie-Virologie, CHU Le Dantec, Université Cheikh Anta Diop, Dakar-Sénégal, Dakar, Senegal., Dia A; Laboratoire Bactériologie-Virologie, CHU Le Dantec, Université Cheikh Anta Diop, Dakar-Sénégal, Dakar, Senegal., Sow-Sall A; Laboratoire Bactériologie-Virologie, CHU Le Dantec, Université Cheikh Anta Diop, Dakar-Sénégal, Dakar, Senegal., Gaye-Diallo A; Laboratoire Bactériologie-Virologie, CHU Le Dantec, Université Cheikh Anta Diop, Dakar-Sénégal, Dakar, Senegal., Mboup S; Laboratoire Bactériologie-Virologie, CHU Le Dantec, Université Cheikh Anta Diop, Dakar-Sénégal, Dakar, Senegal., Touré-Kane C; Laboratoire Bactériologie-Virologie, CHU Le Dantec, Université Cheikh Anta Diop, Dakar-Sénégal, Dakar, Senegal. |
المصدر: | Journal of medical virology [J Med Virol] 2016 May; Vol. 88 (5), pp. 815-9. Date of Electronic Publication: 2015 Nov 04. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7705876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-9071 (Electronic) Linking ISSN: 01466615 NLM ISO Abbreviation: J Med Virol Subsets: MEDLINE |
أسماء مطبوعة: | Publication: New York Ny : Wiley-Liss Original Publication: New York, Liss. |
مواضيع طبية MeSH: | Carrier State/*epidemiology , Hepatitis B/*epidemiology , Hepatitis B Vaccines/*administration & dosage , Hepatitis B virus/*isolation & purification , Vaccination/*statistics & numerical data, Carrier State/prevention & control ; Child, Preschool ; Female ; Hepatitis B/prevention & control ; Hepatitis B Surface Antigens/blood ; Humans ; Infant ; Infant, Newborn ; Male ; Senegal/epidemiology ; Seroepidemiologic Studies |
مستخلص: | Hepatitis B is a major public health problem in Senegal, a country with high prevalence and a transmission occurring mainly during infancy. Only, one 6-8 weeks vaccination campaign was initiated in 2005 and it was part of the expanded program of immunization. The aim of this study was to determine the prevalence of HBsAg in children born from HIV-seropositive mothers by using dried blood specimens. Specimens were collected between July 2007 and November 2012 from children aged 2-48 weeks in Dakar and decentralized sites working on HIV mother-to-child transmission prevention. HBsAg detection was performed using Architect HBsAg Qualitative II kit (Abbott Diagnostics, Ireland) and for all reactive samples confirmation was done using Architect HBsAg Qualitative II Confirmatory kit (Abbott Diagnostics, Ireland). Nine hundred thirty samples were collected throughout the country with 66% out of Dakar, the capital city. The median age was 20 weeks and 88% of children were less than 1 year of age with a sex ratio of 1.27 in favor of boys. HBsAg was detected in 28 cases giving a global prevalence of 3%. According to age, HBsAg prevalences were 5.1% for children less than 6 weeks, 4.1% and 4.6%, respectively, for those aged 12-18 weeks and 18-24 weeks of age. The HIV prevalence was 2.6% with no HIV/HBV co-infection. This study showed a high rate of HBV infection in children under 24 months, highlighting the need to promote birth-dose HBV vaccination as recommended by WHO. (© 2015 Wiley Periodicals, Inc.) |
فهرسة مساهمة: | Keywords: HBsAg; Senegal; dried blood specimens; immunization; infants |
المشرفين على المادة: | 0 (Hepatitis B Surface Antigens) 0 (Hepatitis B Vaccines) |
تواريخ الأحداث: | Date Created: 20151022 Date Completed: 20161213 Latest Revision: 20220409 |
رمز التحديث: | 20240628 |
DOI: | 10.1002/jmv.24409 |
PMID: | 26488892 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1096-9071 |
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DOI: | 10.1002/jmv.24409 |