دورية أكاديمية

Management of type II unruptured cesarean scar pregnancy: Comparison of gestational mass excision and uterine artery embolization combined with methotrexate.

التفاصيل البيبلوغرافية
العنوان: Management of type II unruptured cesarean scar pregnancy: Comparison of gestational mass excision and uterine artery embolization combined with methotrexate.
المؤلفون: Sun YY; Department of Obstetrics and Gynecology, Affiliated First Hospital of Shanghai Jiao Tong University, Shanghai, China., Xi XW; Department of Obstetrics and Gynecology, Affiliated First Hospital of Shanghai Jiao Tong University, Shanghai, China., Yan Q; Department of Obstetrics and Gynecology, Affiliated First Hospital of Shanghai Jiao Tong University, Shanghai, China., Qiao QQ; Department of Obstetrics and Gynecology, Affiliated First Hospital of Shanghai Jiao Tong University, Shanghai, China., Feng YJ; Department of Obstetrics and Gynecology, Affiliated First Hospital of Shanghai Jiao Tong University, Shanghai, China., Zhu YP; Department of Obstetrics and Gynecology, Affiliated First Hospital of Shanghai Jiao Tong University, Shanghai, China. Electronic address: zhuyp63@126.com.
المصدر: Taiwanese journal of obstetrics & gynecology [Taiwan J Obstet Gynecol] 2015 Oct; Vol. 54 (5), pp. 489-92.
نوع المنشور: Comparative Study; Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Country of Publication: China (Republic : 1949- ) NLM ID: 101213819 Publication Model: Print Cited Medium: Internet ISSN: 1875-6263 (Electronic) Linking ISSN: 10284559 NLM ISO Abbreviation: Taiwan J Obstet Gynecol Subsets: MEDLINE
أسماء مطبوعة: Publication: 2007- : Taipei, Taiwan : Elsevier
Original Publication: Hong Kong : Elsevier (Singapore)
مواضيع طبية MeSH: Cesarean Section/*adverse effects , Cicatrix/*surgery , Methotrexate/*administration & dosage , Pregnancy, Ectopic/*surgery , Uterine Artery Embolization/*methods , Uterine Hemorrhage/*therapy , Uterus/*surgery, Abortifacient Agents, Nonsteroidal/administration & dosage ; Adult ; Cicatrix/complications ; Female ; Follow-Up Studies ; Humans ; Laparotomy/methods ; Pregnancy ; Pregnancy, Ectopic/etiology ; Retrospective Studies ; Treatment Outcome ; Uterine Hemorrhage/etiology ; Uterus/blood supply
مستخلص: Objective: This research was carried out to investigate the effectiveness, rationality, and safety of laparotomy management compared with uterine artery embolization (UAE) combined with methotrexate (MTX) for the treatment of deep implantation cesarean scar pregnancy (CSP II).
Materials and Methods: Data from 29 patients seen between June 2008 and February 2012 were retrospectively analyzed. The patients were divided into the surgery group and the UAE combined with MTX group according to the treatment they received. We compared the clinical characteristics and treatment outcomes between the two groups.
Results: The patients' clinical characteristics did not differ between the surgery group and the UAE combined with MTX group. However, the mean blood loss was decreased in the surgery group compared with the UAE combined with MTX group (90 ± 4.5 mL vs. 286 ± 5.2 mL, p < 0.05). No patients required blood transfusion in the surgery group, whereas two patients in the UAE combined with MTX group received blood transfusions. The length of time for the serum beta human chorionic gonadotropin (β-HCG) level to normalize, the time required for the disappearance of the gestational mass, and the duration of hospital stay were significantly less in the surgery group than in the UAE combined with MTX group (13.7 ± 1.0 days vs. 40.7 ± 1.7 days, 7.1 ± 1.3 days vs. 135.4 ± 6.7 days, and 11.0 ± 1.2 days vs. 41.4 ± 3.2 days, respectively; p < 0.01). Although the treatment success rate did not differ significantly between the two groups, the success rate was 100% for the surgery group and 73% for the UAE combined with MTX group.
Conclusion: Surgical treatment can remove gestational masses and allow wound repair. Moreover, laparotomy is available in almost all hospitals. Thus, surgery can be an effective and reasonable treatment for CSP II.
(Copyright © 2015. Published by Elsevier B.V.)
فهرسة مساهمة: Keywords: cesarean scar pregnancy; laparotomy; uterine artery embolization
المشرفين على المادة: 0 (Abortifacient Agents, Nonsteroidal)
YL5FZ2Y5U1 (Methotrexate)
تواريخ الأحداث: Date Created: 20151103 Date Completed: 20160830 Latest Revision: 20151102
رمز التحديث: 20240628
DOI: 10.1016/j.tjog.2015.08.002
PMID: 26522097
قاعدة البيانات: MEDLINE
الوصف
تدمد:1875-6263
DOI:10.1016/j.tjog.2015.08.002