دورية أكاديمية
Identification of two phylogenetic lineages of equine hepacivirus and high prevalence in Brazil.
| العنوان: | Identification of two phylogenetic lineages of equine hepacivirus and high prevalence in Brazil. |
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| المؤلفون: | Figueiredo AS; Laboratory of Viral Hepatitis, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, RJ, 21040-360 Brazil. Electronic address: andreza.figueiredo@ioc.fiocruz.br., Lampe E; Laboratory of Viral Hepatitis, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, RJ, 21040-360 Brazil., do Espírito-Santo MP; Laboratory of Viral Hepatitis, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, RJ, 21040-360 Brazil., Mello FC; Laboratory of Viral Hepatitis, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, RJ, 21040-360 Brazil., de Almeida FQ; Veterinary Institute, Federal Rural University of Rio de Janeiro, UFRRJ, Rio de Janeiro, RJ 23851-970 Brazil., de Lemos ER; Laboratory of Hantaviruses and Rickettsioses, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, RJ, 21040-360 Brazil., Godoi TL; Animal Science Institute, Federal Rural University of Rio de Janeiro, UFRRJ, Rio de Janeiro, RJ, 23851-970 Brazil., Dimache LA; Animal Science Institute, Federal Rural University of Rio de Janeiro, UFRRJ, Rio de Janeiro, RJ, 23851-970 Brazil., Dos Santos DR; Department of Veterinary Microbiology and Immunology, Federal Rural University of Rio de Janeiro, UFRRJ, Rio de Janeiro, RJ, 23851-970 Brazil., Villar LM; Laboratory of Viral Hepatitis, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, RJ, 21040-360 Brazil. |
| المصدر: | Veterinary journal (London, England : 1997) [Vet J] 2015 Dec; Vol. 206 (3), pp. 414-6. Date of Electronic Publication: 2015 Oct 22. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Balliere Tindall Country of Publication: England NLM ID: 9706281 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2971 (Electronic) Linking ISSN: 10900233 NLM ISO Abbreviation: Vet J Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: London : Balliere Tindall Original Publication: London : Ballière Tindall, c1997- |
| مواضيع طبية MeSH: | Hepacivirus/*classification , Hepatitis C/*veterinary , Horse Diseases/*virology, Animals ; Brazil/epidemiology ; Female ; Genetic Variation ; Hepacivirus/genetics ; Hepatitis C/epidemiology ; Hepatitis C/virology ; Horse Diseases/epidemiology ; Horses ; Male ; Phylogeny ; Prevalence |
| مستخلص: | Non-primate hepacivirus (NPHV), as described in horses, is the virus most genetically related to hepatitis C virus (HCV). Although detected worldwide, limited data on genomic variability and distribution of NPHV are available in Latin America. The aim of this study was to investigate the genetic diversity and prevalence of equine NPHV in Brazil. Thirteen percent of 202 equines from three Brazilian states were positive for NPHV genome by reverse transcriptase PCR. Nucleotide sequences of the partial NS5B genome presented the greatest diversity described to date (25.6%), which is comparable to the upper limit of diversity for HCV subtype classification for the same region. Phylogenetic analysis revealed that Brazilian NPHV sequences along with isolates worldwide form two strongly supported clades (pp = 1.0) suggesting the existence of two distinct lineages. (Copyright © 2015 Elsevier Ltd. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Brazil; Horse; Non-primate hepacivirus; Nucleotide distance; Subtype classification |
| تواريخ الأحداث: | Date Created: 20151108 Date Completed: 20161213 Latest Revision: 20161230 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1016/j.tvjl.2015.10.015 |
| PMID: | 26545848 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1532-2971 |
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| DOI: | 10.1016/j.tvjl.2015.10.015 |