دورية أكاديمية
A long-term follow-up of patients with prolonged asystole of greater than 15s on head-up tilt testing.
العنوان: | A long-term follow-up of patients with prolonged asystole of greater than 15s on head-up tilt testing. |
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المؤلفون: | Sau A; Imperial College London, London, United Kingdom., Mereu R; University of Pavia, Department of Internal Medicine, Pavia, Italy., Taraborrelli P; Imperial College Healthcare NHS Trust, Department of Cardiology, London, United Kingdom., Dhutia NM; National Heart and Lung Institute, Hammersmith Hospital, Imperial College London, United Kingdom., Willson K; Imperial College London, London, United Kingdom., Hayat SA; Imperial College Healthcare NHS Trust, Department of Cardiology, London, United Kingdom., Francis DP; Imperial College London, London, United Kingdom; Imperial College Healthcare NHS Trust, Department of Cardiology, London, United Kingdom., Sutton R; Imperial College London, London, United Kingdom; Imperial College Healthcare NHS Trust, Department of Cardiology, London, United Kingdom., Lim PB; Imperial College London, London, United Kingdom; Imperial College Healthcare NHS Trust, Department of Cardiology, London, United Kingdom. Electronic address: pblim@imperial.ac.uk. |
المصدر: | International journal of cardiology [Int J Cardiol] 2016 Jan 15; Vol. 203, pp. 482-5. Date of Electronic Publication: 2015 Oct 21. |
نوع المنشور: | Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
اللغة: | English |
بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8200291 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1874-1754 (Electronic) Linking ISSN: 01675273 NLM ISO Abbreviation: Int J Cardiol Subsets: MEDLINE |
أسماء مطبوعة: | Publication: Amsterdam : Elsevier Original Publication: Amsterdam : Elsevier/North-Holland Biomedical Press, c1981- |
مواضيع طبية MeSH: | Cardiac Pacing, Artificial*/methods , Tilt-Table Test*, Heart Arrest/*diagnosis , Heart Arrest/*therapy, Adult ; Aged ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Pacemaker, Artificial ; Prognosis ; Retrospective Studies ; Surveys and Questionnaires ; Treatment Outcome |
مستخلص: | Background: Head-up tilt (HUT) is used for diagnosis of vasovagal syncope (VVS), and can provoke cardioinhibition. VVS is usually considered benign, however pacemaker insertion may be indicated in some patients. We sought to characterize the long-term outcomes of patients with prolonged asystole (>15s) on HUT. Methods: We conducted a retrospective study on patients with asystole >15s on HUT identified from 5133 patients who were investigated between 1998 and 2012 at our institution. Patients were mailed questionnaires or telephoned to ascertain outcomes. Where contact was not possible, the patients' general practitioners were contacted to request up-to-date information. Results: A total of 26 patients with a mean age of 45 ± 18 years and a mean duration of asystole on HUT of 26 ± 7s were successfully followed up from a total of 77 patients identified. The follow-up duration was 99 ± 39 months. Six patients had undergone pacemaker (PPM) implantation. Of the patients without PPM, 16 reported spontaneously improved symptoms. Ten patients sustained injury prior to HUT compared with one after HUT, when a clear diagnosis was made and management advice was given. There were no major injuries or deaths after HUT. The 6 patients with PPMs had a mean age of 60 ± 16 (67% male) at HUT. Four patients had no further syncope after PPM and two demonstrated improvement but still experienced recurrent syncope. Conclusions: Prolonged asystole (>15s) on tilt does not necessarily predict adverse outcomes with most patients improving spontaneously over the long-term. Pacemaker insertion in selected patients may reduce syncope recurrence but does not always abolish it. (Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.) |
معلومات مُعتمدة: | FS/10/38/28268 United Kingdom BHF_ British Heart Foundation |
فهرسة مساهمة: | Keywords: Asystole; Cardioinhibition; Pacemaker; Syncope; Tilt-table test |
تواريخ الأحداث: | Date Created: 20151109 Date Completed: 20161017 Latest Revision: 20220129 |
رمز التحديث: | 20221213 |
DOI: | 10.1016/j.ijcard.2015.10.090 |
PMID: | 26547742 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1874-1754 |
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DOI: | 10.1016/j.ijcard.2015.10.090 |