دورية أكاديمية

Palliative Senning in the Treatment of Congenital Heart Disease with Severe Pulmonary Hypertension.

التفاصيل البيبلوغرافية
العنوان: Palliative Senning in the Treatment of Congenital Heart Disease with Severe Pulmonary Hypertension.
المؤلفون: Penha JG; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil., Zorzanelli L; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil., Barbosa-Lopes AA; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil., Atik E; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil., Miana LA; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil., Tanamati C; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil., Caneo LF; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil., Miura N; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil., Aiello VD; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil., Jatene MB; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
المصدر: Arquivos brasileiros de cardiologia [Arq Bras Cardiol] 2015 Oct; Vol. 105 (4), pp. 353-61. Date of Electronic Publication: 2015 Aug 18.
نوع المنشور: Journal Article
اللغة: English; Portuguese
بيانات الدورية: Publisher: Sociedad Brasileira De Cardiologia Country of Publication: Brazil NLM ID: 0421031 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1678-4170 (Electronic) Linking ISSN: 0066782X NLM ISO Abbreviation: Arq Bras Cardiol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Sao Paulo : Sociedad Brasileira De Cardiologia
مواضيع طبية MeSH: Arterial Switch Operation/*methods , Hypertension, Pulmonary/*surgery , Palliative Care/*methods , Transposition of Great Vessels/*surgery, Biopsy ; Child ; Child, Preschool ; Female ; Follow-Up Studies ; Heart Atria/surgery ; Humans ; Hypertension, Pulmonary/pathology ; Infant ; Infant, Newborn ; Male ; Medical Illustration ; Oxygen/metabolism ; Quality of Life ; Retrospective Studies ; Time Factors ; Transposition of Great Vessels/pathology ; Treatment Outcome
مستخلص: Background: Transposition of the great arteries (TGA) is the most common cyanotic cardiopathy, with an incidence ranging between 0.2 and 0.4 per 1000 live births. Many patients not treated in the first few months of life may progress with severe pulmonary vascular disease. Treatment of these patients may include palliative surgery to redirect the flow at the atrial level.
Objective: Report our institutional experience with the palliative Senning procedure in children diagnosed with TGA and double outlet right ventricle with severe pulmonary vascular disease, and to evaluate the early and late clinical progression of the palliative Senning procedure.
Methods: Retrospective study based on the evaluation of medical records in the period of 1991 to 2014. Only patients without an indication for definitive surgical treatment of the cardiopathy due to elevated pulmonary pressure were included.
Results: After one year of follow-up there was a mean increase in arterial oxygen saturation from 62.1% to 92.5% and a mean decrease in hematocrit from 49.4% to 36.3%. Lung histological analysis was feasible in 16 patients. In 8 patients, pulmonary biopsy grades 3 and 4 were evidenced.
Conclusion: The palliative Senning procedure improved arterial oxygen saturation, reduced polycythemia, and provided a better quality of life for patients with TGA with ventricular septal defect, severe pulmonary hypertension, and poor prognosis.
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المشرفين على المادة: S88TT14065 (Oxygen)
تواريخ الأحداث: Date Created: 20151113 Date Completed: 20160330 Latest Revision: 20181113
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC4632999
DOI: 10.5935/abc.20150097
PMID: 26559982
قاعدة البيانات: MEDLINE
الوصف
تدمد:1678-4170
DOI:10.5935/abc.20150097