دورية أكاديمية
أعرض في EDS

[Tetanus in Ho Chi Minh City, Vietnam: epidemiological, clinical and outcome features of 389 cases at the Hospital for Tropical Diseases].

التفاصيل البيبلوغرافية
العنوان: [Tetanus in Ho Chi Minh City, Vietnam: epidemiological, clinical and outcome features of 389 cases at the Hospital for Tropical Diseases].
عنوان ترانسليتريتد: Le tétanos à Hô-Chi-Minh-Ville, Vietnam : épidémiologie, clinique et pronostic, à propos de 389 cas à l'Hôpital des maladies tropicales.
المؤلفون: An VT; Institut de la francophonie pour la médecine tropicale, Rue Samsènethai, BP 9519, Vientiane, Laos., Khue PM; Université de médecine et de pharmacie de Haiphong, 72A, Nguyen Binh Khiem, Ngo Quyen, Hai Phong, Vietnam. pmkhue@hpmu.edu.vn., Yen LM; Hôpital des maladies tropicales 190, Ben Ham Tu, Quartier 1, Dist. 5, Hô-Chi-Minh-Ville, Vietnam., Phong ND; Hôpital des maladies tropicales 190, Ben Ham Tu, Quartier 1, Dist. 5, Hô-Chi-Minh-Ville, Vietnam., Strobel M; Institut de la francophonie pour la médecine tropicale, Rue Samsènethai, BP 9519, Vientiane, Laos.
المصدر: Bulletin de la Societe de pathologie exotique (1990) [Bull Soc Pathol Exot] 2015 Dec; Vol. 108 (5), pp. 342-8. Date of Electronic Publication: 2015 Nov 25.
نوع المنشور: English Abstract; Journal Article
اللغة: French
بيانات الدورية: Publisher: Lavoisier Country of Publication: France NLM ID: 9212564 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1961-9049 (Electronic) Linking ISSN: 00379085 NLM ISO Abbreviation: Bull Soc Pathol Exot Subsets: MEDLINE
أسماء مطبوعة: Publication: [Paris] : Lavoisier
Original Publication: Paris : Masson, [1990-
مواضيع طبية MeSH: Tetanus/*epidemiology, Acute Kidney Injury/etiology ; Acute Kidney Injury/mortality ; Adult ; Clostridium tetani/isolation & purification ; Female ; Humans ; Intestinal Absorption ; Intestines/microbiology ; Male ; Metalloendopeptidases/pharmacokinetics ; Middle Aged ; Respiration, Artificial ; Retrospective Studies ; Risk Factors ; Sepsis/etiology ; Sepsis/mortality ; Severity of Illness Index ; Shock, Cardiogenic/etiology ; Shock, Cardiogenic/mortality ; Survival Rate ; Tetanus/complications ; Tetanus/therapy ; Tetanus Toxin/pharmacokinetics ; Tracheotomy ; Treatment Outcome ; Vietnam/epidemiology ; Wound Infection/epidemiology
مستخلص: The objective of this study is to describe the different aspects of tetanus during the past recent years in southern Vietnam: epidemiology, clinical picture, management, and death risk factors. It is a retrospective study concerning 389 cases admitted in 2007 and 2008 at the reference Hospital for Tropical Diseases in Ho Chi Minh City. 93% of all cases were generalized tetanus, and 50% were severe cases. A majority of patients were adult males (medium age 43, M/ F sex-ratio 2.9). Half of them underwent tracheotomy and 39% assisted ventilation. Case fatality rate was 6.4%, the lowest reported rate worldwide in the last ten years. Fatalities resulted mainly from neuro-vegetative disorders, essentially cardiogenic shock (28% of all deaths) [OR = 16.95; p < 0.001], sepsis (24%) [OR = 3.25; (p < 0,114], and acute renal failure (16%) [OR = 7,22; p < 0.004]. Age over 60-year [OR = 4.53; p < 0.0001] and a leukocyte count>12.000/mm(3) [OR = 2.32; p < 0.020] were significantly associated with fatal outcome, contrarily to incubation and extension phase durations, or delayed serum administration. Systematic extension of vaccination to all adult males, and improved access to post exposure sero-immunization at all levels of health centres throughout the country may further reduce tetanus burden in Vietnam.
فهرسة مساهمة: Keywords: Clostridium tetani; Ho Chi Minh City; Hospital; South East Asia; Tetanus; Vietnam
المشرفين على المادة: 0 (Tetanus Toxin)
11032-48-7 (tetanospasmin)
EC 3.4.24.- (Metalloendopeptidases)
تواريخ الأحداث: Date Created: 20151127 Date Completed: 20160920 Latest Revision: 20151215
رمز التحديث: 20231215
DOI: 10.1007/s13149-015-0450-5
PMID: 26608271
قاعدة البيانات: MEDLINE
الوصف
تدمد:1961-9049
DOI:10.1007/s13149-015-0450-5