دورية أكاديمية
Clinical performance of a novel ultrathin strut, low-dose, sirolimus-eluting stent with abluminal-only biodegradable polymeric coating for patients undergoing percutaneous coronary intervention in the daily practice.
| العنوان: | Clinical performance of a novel ultrathin strut, low-dose, sirolimus-eluting stent with abluminal-only biodegradable polymeric coating for patients undergoing percutaneous coronary intervention in the daily practice. |
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| المؤلفون: | Prado GF Jr; Department of Interventional Cardiology, Heart Institute-InCor, University of São Paulo, São Paulo, Brazil., Ribeiro EE; Department of Interventional Cardiology, Heart Institute-InCor, University of São Paulo, São Paulo, Brazil., Melo PH; Department of Interventional Cardiology, Heart Institute-InCor, University of São Paulo, São Paulo, Brazil., Pinton FA; Department of Interventional Cardiology, Heart Institute-InCor, University of São Paulo, São Paulo, Brazil., Esteves-Filho A; Department of Interventional Cardiology, Heart Institute-InCor, University of São Paulo, São Paulo, Brazil., Takimura CK; Department of Interventional Cardiology, Heart Institute-InCor, University of São Paulo, São Paulo, Brazil., Mariani J Jr; Department of Interventional Cardiology, Heart Institute-InCor, University of São Paulo, São Paulo, Brazil., Kajita LJ; Department of Interventional Cardiology, Heart Institute-InCor, University of São Paulo, São Paulo, Brazil., Marchiori G; Department of Interventional Cardiology, Heart Institute-InCor, University of São Paulo, São Paulo, Brazil., Araripe Falcao Bde A; Department of Interventional Cardiology, Heart Institute-InCor, University of São Paulo, São Paulo, Brazil., Galon MZ; Department of Interventional Cardiology, Heart Institute-InCor, University of São Paulo, São Paulo, Brazil., Soares PR; Department of Interventional Cardiology, Heart Institute-InCor, University of São Paulo, São Paulo, Brazil., Zalc S; Department of Interventional Cardiology, Heart Institute-InCor, University of São Paulo, São Paulo, Brazil., Lemos PA; Department of Interventional Cardiology, Heart Institute-InCor, University of São Paulo, São Paulo, Brazil. |
| المصدر: | Cardiovascular diagnosis and therapy [Cardiovasc Diagn Ther] 2015 Dec; Vol. 5 (6), pp. 414-9. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: AME Publishing Company Country of Publication: China NLM ID: 101601613 Publication Model: Print Cited Medium: Print ISSN: 2223-3652 (Print) Linking ISSN: 22233652 NLM ISO Abbreviation: Cardiovasc Diagn Ther Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Publication: SHEUNG WAN, Hong Kong : AME Publishing Company Original Publication: Hangzhou, China : CDT Office, [2011]- |
| مستخلص: | Background: The present study aimed to evaluate the clinical performance, in the daily practice of a busy catheterization laboratory, of a novel drug-eluting stent (DES) built with an ultra-thin-strut metallic platform, eluting sirolimus at low doses, abluminal coated with biodegradable polymers, and mounted in a low-compliant delivery system. Methods: Prospective, single-arm study, comprising all consecutive patients undergoing percutaneous coronary intervention (PCI) with the Inspiron™ sirolimus-eluting stent (SES) (Scitech, Aparecida de Goiania, Brazil). The primary endpoint was the occurrence of major adverse cardiac events (MACE) [cardiac death, non-PCI related myocardial infarction (MI), or target vessel revascularization (TVR)]. Results: A total of 470 patients were included, from which 51.3% were diabetics, 33.8% had triple-vessel disease, 15.3% had heart failure, 38.9% had at least one bifurcation treated, 19.8% were treated for a bare metal stent restenosis, and 61.9% had at least one type C lesion; one or more of these features were found in 96.0%. At 300 days, the rate target lesion revascularization was 5.4% and the rate of MACE was 8.1%. The incidence of definite or probable stent thrombosis was 0.4%, with no cases between 30 and 300 days. Conclusions: The novel stent is associated with excellent short and mid-term clinical outcomes in patients treated with PCI in the daily practice. |
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| فهرسة مساهمة: | Keywords: Biodegradable polymer; complex lesions; drug-eluting stent (DES); sirolimus-eluting stent (SES); stent thrombosis |
| تواريخ الأحداث: | Date Created: 20151218 Date Completed: 20151217 Latest Revision: 20201001 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC4666690 |
| DOI: | 10.3978/j.issn.2223-3652.2015.07.07 |
| PMID: | 26675281 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 2223-3652 |
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| DOI: | 10.3978/j.issn.2223-3652.2015.07.07 |