التفاصيل البيبلوغرافية
| العنوان: |
Low frequency overactivation in dyslexia: Evidence from resting state Magnetoencephalography. |
| المؤلفون: |
Pagnotta MF, Zouridakis G, Lianyang Li, Lizarazu M, Lallier M, Molinaro N, Carreiras M |
| المصدر: |
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference [Annu Int Conf IEEE Eng Med Biol Soc] 2015; Vol. 2015, pp. 6959-62. |
| نوع المنشور: |
Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: |
English |
| بيانات الدورية: |
Publisher: [IEEE] Country of Publication: United States NLM ID: 101763872 Publication Model: Print Cited Medium: Internet ISSN: 2694-0604 (Electronic) Linking ISSN: 23757477 NLM ISO Abbreviation: Annu Int Conf IEEE Eng Med Biol Soc Subsets: MEDLINE |
| أسماء مطبوعة: |
Original Publication: [Piscataway, NJ] : [IEEE], [2007]- |
| مواضيع طبية MeSH: |
Brain Mapping* , Rest*, Dyslexia/*physiopathology , Magnetoencephalography/*methods, Female ; Humans ; Male ; Young Adult |
| مستخلص: |
In this study, we compared the brain activation profiles obtained from resting state Magnetoencephalographic (MEG) activity in 15 dyslexic patients with the profiles of 15 normal controls, using power spectral density (PSD) analysis. We first estimated intracranial dipolar MEG sources on a dense grid on the cortical surface and then projected these sources on a standardized atlas with 68 regions of interest (ROIs). Averaging the PSD values of all sources in each ROI across all control subjects resulted in a normative database that was used to convert the PSD values of dyslexic patients into z-scores in eight distinct frequency bands. We found that dyslexic patients exhibited statistically significant overactivation in the delta band (0.1-4 Hz) in the right temporal (entorhinal and insula), left inferior frontal (Broca's area), and right inferior frontal regions. Overactivation may be interpreted as a compensatory mechanism for reading characterizing dyslexic patients. These findings suggest that resting-state MEG activation maps may be used as specific biomarkers that can help with the diagnosis of and assess the efficacy of intervention in dyslexia. |
| تواريخ الأحداث: |
Date Created: 20160107 Date Completed: 20160926 Latest Revision: 20200928 |
| رمز التحديث: |
20221213 |
| DOI: |
10.1109/EMBC.2015.7319993 |
| PMID: |
26737893 |
| قاعدة البيانات: |
MEDLINE |
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