دورية أكاديمية
Assessing genotoxic effects in fish from a marine protected area influenced by former mining activities and other stressors.
| العنوان: | Assessing genotoxic effects in fish from a marine protected area influenced by former mining activities and other stressors. |
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| المؤلفون: | Gusso-Choueri PK; Graduate Program in Ecology and Conservation, Federal University of Paraná (UFPR), CP 19031, CEP 81531-990 Curitiba, PR, Brazil; Cellular Toxicology Laboratory, Department of Cellular Biology, Federal University of Paraná (UFPR), CP19031, 81531-990 Curitiba, PR, Brazil; Laboratory for the Study of Aquatic Pollution and Ecotoxicology (NEPEA), São Paulo State University, São Vicente Campus (UNESP Campus do Litoral Paulista), Praça Infante Dom Henrique, s/n, CP 11330-900 São Vicente, SP, Brazil. Electronic address: pchoueri@ufpr.br., Choueri RB; Department of Marine Sciences, Federal University of São Paulo, Santos Campus (UNIFESP - Santos), Av. Almirante Saldanha da Gama, 89, CP 11030-490 Santos, SP, Brazil., Santos GS; Graduate Program in Ecology and Conservation, Federal University of Paraná (UFPR), CP 19031, CEP 81531-990 Curitiba, PR, Brazil; Genetics Department, Federal University of Paraná (UFPR), 81531-990 Curitiba, PR, Brazil., de Araújo GS; Laboratory for the Study of Aquatic Pollution and Ecotoxicology (NEPEA), São Paulo State University, São Vicente Campus (UNESP Campus do Litoral Paulista), Praça Infante Dom Henrique, s/n, CP 11330-900 São Vicente, SP, Brazil; Institute of Oceanography, University of São Paulo (IOUSP), Praça do Oceanográfico, 191, CEP 05508-120 São Paulo, SP, Brazil., Cruz AC; Laboratory for the Study of Aquatic Pollution and Ecotoxicology (NEPEA), São Paulo State University, São Vicente Campus (UNESP Campus do Litoral Paulista), Praça Infante Dom Henrique, s/n, CP 11330-900 São Vicente, SP, Brazil; Institute of Oceanography, University of São Paulo (IOUSP), Praça do Oceanográfico, 191, CEP 05508-120 São Paulo, SP, Brazil., Stremel T; Research Group on Environmental and Sanitary Analytical Chemistry (QAAS), Ponta Grossa State University, Av. General Carlos Cavalcanti, 4748, CEP 84030-900 Ponta Grossa, Brazil., de Campos SX; Research Group on Environmental and Sanitary Analytical Chemistry (QAAS), Ponta Grossa State University, Av. General Carlos Cavalcanti, 4748, CEP 84030-900 Ponta Grossa, Brazil., Cestari MM; Graduate Program in Ecology and Conservation, Federal University of Paraná (UFPR), CP 19031, CEP 81531-990 Curitiba, PR, Brazil; Genetics Department, Federal University of Paraná (UFPR), 81531-990 Curitiba, PR, Brazil., Ribeiro CA; Graduate Program in Ecology and Conservation, Federal University of Paraná (UFPR), CP 19031, CEP 81531-990 Curitiba, PR, Brazil; Cellular Toxicology Laboratory, Department of Cellular Biology, Federal University of Paraná (UFPR), CP19031, 81531-990 Curitiba, PR, Brazil., Abessa DM; Laboratory for the Study of Aquatic Pollution and Ecotoxicology (NEPEA), São Paulo State University, São Vicente Campus (UNESP Campus do Litoral Paulista), Praça Infante Dom Henrique, s/n, CP 11330-900 São Vicente, SP, Brazil. |
| المصدر: | Marine pollution bulletin [Mar Pollut Bull] 2016 Mar 15; Vol. 104 (1-2), pp. 229-39. Date of Electronic Publication: 2016 Jan 25. |
| نوع المنشور: | Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: England NLM ID: 0260231 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3363 (Electronic) Linking ISSN: 0025326X NLM ISO Abbreviation: Mar Pollut Bull Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2003- : Oxford : Elsevier Original Publication: London, Macmillan. |
| مواضيع طبية MeSH: | Catfishes* , DNA Damage* , Environmental Exposure*, Mutagenicity Tests/*veterinary , Water Pollutants, Chemical/*toxicity, Animals ; Brazil ; Comet Assay/methods ; Comet Assay/veterinary ; Environmental Monitoring ; Micronucleus Tests/methods ; Micronucleus Tests/veterinary ; Mining ; Mutagenicity Tests/methods |
| مستخلص: | The goal of the current study was to evaluate different genotoxicity tools in order to assess a marine protected area (MPA) affected by former mining activities and urban settlements. A catfish (Cathorops spixii) was analyzed for genotoxic effects at the (i) molecular and at the (ii) chromosomal levels. Through factor analysis, genotoxicity was found to be linked to levels of metals bioaccumulated and PAH metabolites in the bile. Micronucleus and nuclear alteration were less vulnerable to the effects of confounding factors in mildly contaminated areas since they were more frequently associated with bioaccumulated metals than the DNA analysis. The different genotoxicity responses allowed for the identification of sources of pollution in the MPA. This approach was important for detecting environmental risks related to genotoxic contaminants in a mildly contaminated MPA. (Copyright © 2016 Elsevier Ltd. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Biomarkers; Environmental quality assessment; Estuary; Genotoxicity; Multivariate approach; Weight of evidence |
| المشرفين على المادة: | 0 (Water Pollutants, Chemical) |
| تواريخ الأحداث: | Date Created: 20160130 Date Completed: 20161215 Latest Revision: 20181202 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1016/j.marpolbul.2016.01.025 |
| PMID: | 26822909 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1879-3363 |
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| DOI: | 10.1016/j.marpolbul.2016.01.025 |