دورية أكاديمية
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Imazapyr+imazapic herbicide determines acute toxicity in silver catfish Rhamdia quelen.

التفاصيل البيبلوغرافية
العنوان: Imazapyr+imazapic herbicide determines acute toxicity in silver catfish Rhamdia quelen.
المؤلفون: Golombieski JI; Department of Agricultural and Environmental Sciences, Federal University of Santa Maria (UFSM)/CESNORS, Linha 7 de Setembro, BR 386, Km 40, Frederico Westphalen, 98400-000 RS, Brazil. Electronic address: jgolombieski2012@gmail.com., Sutili FJ; Department of Physiology and Pharmacology, UFSM, Avenida Roraima 1000, Santa Maria (SM), 97105-900 RS, Brazil. Electronic address: sutilifj@gmail.com., Salbego J; Department of Physiology and Pharmacology, UFSM, Avenida Roraima 1000, Santa Maria (SM), 97105-900 RS, Brazil. Electronic address: josalbego2004@yahoo.com.br., Seben D; Department of Agricultural and Environmental Sciences, Federal University of Santa Maria (UFSM)/CESNORS, Linha 7 de Setembro, BR 386, Km 40, Frederico Westphalen, 98400-000 RS, Brazil. Electronic address: debyseben@hotmail.com., Gressler LT; Department of Physiology and Pharmacology, UFSM, Avenida Roraima 1000, Santa Maria (SM), 97105-900 RS, Brazil. Electronic address: lutgressler@hotmail.com., da Cunha JA; Department of Physiology and Pharmacology, UFSM, Avenida Roraima 1000, Santa Maria (SM), 97105-900 RS, Brazil. Electronic address: jessyka.arruda@hotmail.com., Gressler LT; Department of Preventive Veterinary Medicine, UFSM, Avenida Roraima 1000, SM, 97105-900 RS, Brazil. Electronic address: letrevi@gmail.com., Zanella R; Department of Chemistry, UFSM, Avenida Roraima 1000, SM, 97105-900 RS, Brazil. Electronic address: larp_rz@yahoo.com.br., Vaucher Rde A; Graduate Program in Nanoscience, Franciscan University, Rua dos Andradas 1614, SM, 97010-032 RS, Brazil. Electronic address: rodvaucher@hotmail.com., Marchesan E; Department of Plant Science, UFSM, Avenida Roraima 1000, SM, 97105-900 RS, Brazil. Electronic address: eniomarchesan@gmail.com., Baldisserotto B; Department of Physiology and Pharmacology, UFSM, Avenida Roraima 1000, Santa Maria (SM), 97105-900 RS, Brazil. Electronic address: bbaldisserotto@hotmail.com.
المصدر: Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2016 Jun; Vol. 128, pp. 91-9. Date of Electronic Publication: 2016 Feb 19.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7805381 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2414 (Electronic) Linking ISSN: 01476513 NLM ISO Abbreviation: Ecotoxicol Environ Saf Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Amsterdam, Netherlands : Elsevier
مواضيع طبية MeSH: Catfishes/*blood , Herbicides/*toxicity , Imidazoles/*toxicity , Immunity, Innate/*drug effects , Niacin/*analogs & derivatives , Nicotinic Acids/*toxicity , Water Pollutants, Chemical/*toxicity, Animals ; Aspartate Aminotransferases/blood ; Blood Glucose/analysis ; Catfishes/immunology ; Catfishes/metabolism ; Gills/drug effects ; Gills/immunology ; Gills/metabolism ; Herbicides/analysis ; Imidazoles/analysis ; Muscles/drug effects ; Muscles/immunology ; Muscles/metabolism ; Niacin/analysis ; Niacin/toxicity ; Nicotinic Acids/analysis ; Potassium/blood ; Sodium/blood ; Toxicity Tests, Acute ; Water Pollutants, Chemical/analysis
مستخلص: Imazapyr (IMY) and imazapic (IMI) are imidazolinone herbicides which have been associated in a commercial formulation (Kifix(®)). To date, there are no studies on the toxicity of an IMY+IMI herbicide in fish. This work aimed to assess the acute toxicity (24 and 96 h) of IMY+IMI (0, 0.488 and 4.88 µg/L) towards Rhamdia quelen through hematological, biochemical, immunological, ionoregulatory and enzymatic indexes. Red blood cell count was lower at 4.88 than at 0.488 µg/L (24 and 96 h); mean corpuscular volume was lower than control at both concentrations (24 h) and at 0.488 µg/L (96 h); lymphocytes declined at 4.88 µg/L comparing to control (96 h); and monocytes increased at 4.88 µg/L (96 h) in comparison with the respective control and with 4.88 µg/L at 24h. Aspartate aminotransferase was higher at 0.488 µg/L (96 h) than the respective control and the respective concentration at 24 h; uric acid reduced at 4.88 µg/L comparing with 0.488 µg/L (96 h); and cortisol was lower at 4.88 µg/L compared to 0.488 µg/L and control (96 h). Herbicide exposure lowered plasma bactericidal activity at both concentrations (24 h) and at 0.488 µg/L (96 h); and plasma complement activity declined at 4.88 µg/L comparing with 0.488 µg/L and control (96 h), and was lower at all concentrations at 96 h than at 24 h. Plasma K(+) levels were higher at 4.88µg/L than in the remaining groups (24 and 96h); and Na(+) levels decreased at 4.88 µg/L compared to control (96 h). Na(+)/K(+)-ATPase and H(+)-ATPase activities in gills were lower at 4.88 µg/L comparing with control (24 h) and with the respective concentration at 96 h; and AChE activity in brain was higher at 0.488 and 4.88 µg/L than control (24 h) and the respective concentrations at 96 h, while in muscle it was higher at 0.488 and 4.88 µg/L than control (96 h) and the respective concentrations at 24 h. The present findings demonstrate that, despite IMY+IMI targets the animal-absent AHAS enzyme, such formulation displayed an acute toxic effect upon R. quelen homeostasis by impacting on vital functions such as immune defense, metabolism, ionoregulation and neurotransmission.
(Copyright © 2016 Elsevier Inc. All rights reserved.)
فهرسة مساهمة: Keywords: AChE; ATPases; Blood cells; Cortisol; Natural immunity; Plasma ions
المشرفين على المادة: 0 (Blood Glucose)
0 (Herbicides)
0 (Imidazoles)
0 (Nicotinic Acids)
0 (Water Pollutants, Chemical)
2679MF687A (Niacin)
787MX0M5A6 (imazapyr)
9NEZ333N27 (Sodium)
EC 2.6.1.1 (Aspartate Aminotransferases)
K98N09T10R (imazapic)
RWP5GA015D (Potassium)
تواريخ الأحداث: Date Created: 20160222 Date Completed: 20161104 Latest Revision: 20181202
رمز التحديث: 20231215
DOI: 10.1016/j.ecoenv.2016.02.010
PMID: 26896896
قاعدة البيانات: MEDLINE
الوصف
تدمد:1090-2414
DOI:10.1016/j.ecoenv.2016.02.010