دورية أكاديمية
Integrative Medicine for Relief of Nausea and Vomiting in the Treatment of Colorectal Cancer Using Oxaliplatin-Based Chemotherapy: A Systematic Review and Meta-Analysis.
| العنوان: | Integrative Medicine for Relief of Nausea and Vomiting in the Treatment of Colorectal Cancer Using Oxaliplatin-Based Chemotherapy: A Systematic Review and Meta-Analysis. |
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| المؤلفون: | Chen MH; The China-Australia International Research Centre for Chinese Medicine, School of Health Sciences, RMIT University, Bundoora, VIC, 3083, Australia., May BH; The China-Australia International Research Centre for Chinese Medicine, School of Health Sciences, RMIT University, Bundoora, VIC, 3083, Australia., Zhou IW; The China-Australia International Research Centre for Chinese Medicine, School of Health Sciences, RMIT University, Bundoora, VIC, 3083, Australia., Zhang AL; The China-Australia International Research Centre for Chinese Medicine, School of Health Sciences, RMIT University, Bundoora, VIC, 3083, Australia., Xue CC; The China-Australia International Research Centre for Chinese Medicine, School of Health Sciences, RMIT University, Bundoora, VIC, 3083, Australia.; Guangdong Provincial Academy of Chinese Medical Sciences and Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China. |
| المصدر: | Phytotherapy research : PTR [Phytother Res] 2016 May; Vol. 30 (5), pp. 741-53. Date of Electronic Publication: 2016 Feb 23. |
| نوع المنشور: | Journal Article; Meta-Analysis; Review; Systematic Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley Country of Publication: England NLM ID: 8904486 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1099-1573 (Electronic) Linking ISSN: 0951418X NLM ISO Abbreviation: Phytother Res Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Original Publication: London : Heyden & Son, c1987- |
| مواضيع طبية MeSH: | Antiemetics/*therapeutic use , Antineoplastic Agents/*adverse effects , Colorectal Neoplasms/*drug therapy , Integrative Medicine/*methods , Nausea/*drug therapy , Organoplatinum Compounds/*adverse effects , Vomiting/*drug therapy, Animals ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Female ; Humans ; Organoplatinum Compounds/administration & dosage ; Organoplatinum Compounds/therapeutic use ; Oxaliplatin |
| مستخلص: | The management of chemotherapy-induced nausea and vomiting (CINV) remains an issue in the treatment of colorectal cancer using oxaliplatin-based regimens. Certain traditional plant-based medicines (TMs) have histories of use for nausea and vomiting and have been integrated with conventional therapies for CINV. To assess the effectiveness of integrative management of CINV, meta-analysis was conducted of 27 randomised controlled studies (1843 participants) published from 2005 to 2013. The oxaliplatin plus TM groups showed significantly reduced CINV (risk ratio 0.65 [0.59, 0.71], I(2) = 28%) compared with oxaliplatin controls, with or without the addition of conventional anti-emetics. Further sensitivity analyses based on the ingredients of the TMs identified six plants (Atractylodes macrocephala, Poria cocos, Coix lacryma-jobi, Astragalus membranaceus, Glycyrrhiza uralensis and Panax ginseng) that were associated with significant reductions in CINV without important heterogeneity. Experimental studies of these six plants have reported inhibitory effects on nausea and vomiting (or its animal equivalent), regulation of gastrointestinal motility, gastroprotective effects and antioxidant actions, which may at least partially explain the effects identified in the meta-analyses of the clinical trial results. These plants warrant further clinical research as potential additions to chemotherapy regimens in patients whose CINV is not sufficiently well controlled by conventional therapies. Copyright © 2016 John Wiley & Sons, Ltd. (Copyright © 2016 John Wiley & Sons, Ltd.) |
| فهرسة مساهمة: | Keywords: colorectal cancer; integrative medicine; natural products; nausea and vomiting; oxaliplatin; systematic review; traditional medicine |
| المشرفين على المادة: | 0 (Antiemetics) 0 (Antineoplastic Agents) 0 (Organoplatinum Compounds) 04ZR38536J (Oxaliplatin) |
| تواريخ الأحداث: | Date Created: 20160226 Date Completed: 20170330 Latest Revision: 20220409 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1002/ptr.5586 |
| PMID: | 26912094 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1099-1573 |
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| DOI: | 10.1002/ptr.5586 |