دورية أكاديمية
The evolution of diabetic ketoacidosis: An update of its etiology, pathogenesis and management.
| العنوان: | The evolution of diabetic ketoacidosis: An update of its etiology, pathogenesis and management. |
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| المؤلفون: | Nyenwe EA; Division of Endocrinology, Diabetes and Metabolism, University of Tennessee Health Science Center, 920 Madison Ave., Suite 300A, Memphis, TN 38163. Electronic address: enyenwe@uthsc.edu., Kitabchi AE; Division of Endocrinology, Diabetes and Metabolism, University of Tennessee Health Science Center, 920 Madison Ave., Suite 300A, Memphis, TN 38163. |
| المصدر: | Metabolism: clinical and experimental [Metabolism] 2016 Apr; Vol. 65 (4), pp. 507-21. Date of Electronic Publication: 2015 Dec 19. |
| نوع المنشور: | Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Inc Country of Publication: United States NLM ID: 0375267 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8600 (Electronic) Linking ISSN: 00260495 NLM ISO Abbreviation: Metabolism Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: New York, NY : Elsevier Inc. Original Publication: New York, Grune & Stratton. |
| مواضيع طبية MeSH: | Diabetic Ketoacidosis/*pathology , Diabetic Ketoacidosis/*therapy, Animals ; Diabetes Mellitus/therapy ; Diabetic Ketoacidosis/diagnosis ; Diabetic Ketoacidosis/etiology ; Humans ; Incidence |
| مستخلص: | The prognosis of diabetic ketoacidosis has undergone incredibly remarkable evolution since the discovery of insulin nearly a century ago. The incidence and economic burden of diabetic ketoacidosis have continued to rise but its mortality has decreased to less than 1% in good centers. Improved outcome is attributable to a better understanding of the pathophysiology of the disease and widespread application of treatment guidelines. In this review, we present the changes that have occurred over the years, highlighting the evidence behind the recommendations that have improved outcome. We begin with a discussion of the precipitants and pathogenesis of DKA as a prelude to understanding the rationale for the recommendations. A brief review of ketosis-prone type 2 diabetes, an update relating to the diagnosis of DKA and a future perspective are also provided. (Copyright © 2016 Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Diabetic ketoacidosis; Etiology; Management; Pathogenesis |
| تواريخ الأحداث: | Date Created: 20160316 Date Completed: 20160725 Latest Revision: 20220410 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1016/j.metabol.2015.12.007 |
| PMID: | 26975543 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1532-8600 |
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| DOI: | 10.1016/j.metabol.2015.12.007 |