دورية أكاديمية

Cement Dust Exposure and Perturbations in Some Elements and Lung and Liver Functions of Cement Factory Workers.

التفاصيل البيبلوغرافية
العنوان: Cement Dust Exposure and Perturbations in Some Elements and Lung and Liver Functions of Cement Factory Workers.
المؤلفون: Richard EE; Department of Medical Laboratory Science, Faculty of Allied Medical Sciences, College of Medical Sciences, University of Calabar, Calabar 543000, Nigeria., Augusta Chinyere NA; Department of Medical Laboratory Science, Faculty of Allied Medical Sciences, College of Medical Sciences, University of Calabar, Calabar 543000, Nigeria., Jeremaiah OS; Department of Medical Laboratory Science, Faculty of Allied Medical Sciences, College of Medical Sciences, University of Calabar, Calabar 543000, Nigeria., Opara UC; Department of Medical Laboratory Science, Faculty of Allied Medical Sciences, College of Medical Sciences, University of Calabar, Calabar 543000, Nigeria., Henrieta EM; Department of Medical Laboratory Science, Faculty of Allied Medical Sciences, College of Medical Sciences, University of Calabar, Calabar 543000, Nigeria., Ifunanya ED; Department of Medical Laboratory Science, Faculty of Allied Medical Sciences, College of Medical Sciences, University of Calabar, Calabar 543000, Nigeria.
المصدر: Journal of toxicology [J Toxicol] 2016; Vol. 2016, pp. 6104719. Date of Electronic Publication: 2016 Feb 11.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Hindawi Pub. Corp Country of Publication: Egypt NLM ID: 101519097 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1687-8191 (Print) Linking ISSN: 16878191 NLM ISO Abbreviation: J Toxicol Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: [Cairo, Egypt] : Hindawi Pub. Corp., 2008-
مستخلص: Background. Cement dust inhalation is associated with deleterious health effects. The impact of cement dust exposure on the peak expiratory flow rate (PEFR), liver function, and some serum elements in workers and residents near cement factory were assessed. Methods. Two hundred and ten subjects (50 workers, 60 residents, and 100 controls) aged 18-60 years were studied. PEFR, liver function {aspartate and alanine transaminases (AST and ALT) and total and conjugated bilirubin (TB and CB)}, and serum elements {lead (Pb), copper (Cu), manganese (Mn), iron (Fe), cadmium (Cd), selenium (Se), chromium (Cr), zinc (Zn), and arsenic (As)} were determined using peak flow meter, colorimetry, and atomic absorption spectrometry, respectively. Data were analysed using ANOVA and correlation at p = 0.05. Results. The ALT, TB, CB, Pb, As, Cd, Cr, Se, Mn, and Cu were significantly higher and PEFR, Fe, and Zn lower in workers and residents compared to controls (p < 0.05). Higher levels of ALT, AST, and Fe and lower levels of Pb, Cd, Cr, Se, Mn, and Cu were seen in cement workers compared to residents (p < 0.05). Negative correlation was observed between duration of exposure and PEFR (r = -0.416, p = 0.016) in cement workers. Conclusions. Cement dust inhalation may be associated with alterations in serum elements levels and lung and liver functions while long term exposure lowers peak expiratory flow rate.
References: Med J Malaysia. 2000 Mar;55(1):51-7. (PMID: 11072491)
Int J Environ Res Public Health. 2013 Jan 16;10(1):390-8. (PMID: 23325026)
BMC Pulm Med. 2010 Apr 14;10:19. (PMID: 20398255)
Part Fibre Toxicol. 2014 Oct 02;11:51. (PMID: 25272992)
Clin Chem. 1961 Dec;7:603-25. (PMID: 14040183)
BMC Public Health. 2012 Nov 20;12:999. (PMID: 23164428)
Int J Occup Environ Health. 2014 Apr-Jun;20(2):146-56. (PMID: 24999850)
J Occup Environ Med. 2003 Sep;45(9):1008-14. (PMID: 14506344)
Thorax. 1978 Apr;33(2):219-27. (PMID: 663882)
Niger J Physiol Sci. 2008 Jun-Dec;23(1-2):111-4. (PMID: 19434225)
West Afr J Med. 1990 Jul-Sep;9(3):187-92. (PMID: 2271430)
Br Med J. 1959 Nov 21;2(5159):1041-6. (PMID: 13846051)
Am J Clin Pathol. 1957 Jul;28(1):56-63. (PMID: 13458125)
Clin Biochem. 2006 May;39(5):498-510. (PMID: 16730254)
تواريخ الأحداث: Date Created: 20160317 Date Completed: 20160316 Latest Revision: 20201001
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC4766340
DOI: 10.1155/2016/6104719
PMID: 26981118
قاعدة البيانات: MEDLINE
الوصف
تدمد:1687-8191
DOI:10.1155/2016/6104719