دورية أكاديمية
أعرض في EDS

The role of obesity measures in the development and persistence of major depressive disorder.

التفاصيل البيبلوغرافية
العنوان: The role of obesity measures in the development and persistence of major depressive disorder.
المؤلفون: Gibson-Smith D; Department of Psychiatry/ EMGO+ Institute for Health and Care Research, VU University Medical Center, and GGZ inGeest Amsterdam, The Netherlands. Electronic address: d.gibson-smith@ggzingeest.nl., Bot M; Department of Psychiatry/ EMGO+ Institute for Health and Care Research, VU University Medical Center, and GGZ inGeest Amsterdam, The Netherlands., Paans NP; Department of Psychiatry/ EMGO+ Institute for Health and Care Research, VU University Medical Center, and GGZ inGeest Amsterdam, The Netherlands., Visser M; Department of Health Sciences, Faculty of Earth and Life Sciences and EMGO+ Institute for Health and Care Research, VU University, Amsterdam, The Netherlands; Department of Nutrition and Dietetics, Internal Medicine, VU University Medical Center, The Netherlands., Brouwer I; Department of Health Sciences, Faculty of Earth and Life Sciences and EMGO+ Institute for Health and Care Research, VU University, Amsterdam, The Netherlands., Penninx BW; Department of Psychiatry/ EMGO+ Institute for Health and Care Research, VU University Medical Center, and GGZ inGeest Amsterdam, The Netherlands.
المصدر: Journal of affective disorders [J Affect Disord] 2016 Jul 01; Vol. 198, pp. 222-9. Date of Electronic Publication: 2016 Mar 11.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7906073 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2517 (Electronic) Linking ISSN: 01650327 NLM ISO Abbreviation: J Affect Disord Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Amsterdam, Elsevier/North-Holland Biomedical Press.
مواضيع طبية MeSH: Depressive Disorder, Major/*epidemiology , Depressive Disorder, Major/*psychology , Obesity/*epidemiology , Obesity/*psychology, Adolescent ; Adult ; Aged ; Body Mass Index ; Comorbidity ; Female ; Follow-Up Studies ; Humans ; Incidence ; Longitudinal Studies ; Male ; Middle Aged ; Netherlands ; Odds Ratio ; Risk Factors ; Waist Circumference ; Young Adult
مستخلص: Background: The role of obesity with the development of major depressive disorder (MDD) requires conformation and whether obesity contributes to more chronic depression in persons with established (MDD) is unknown. This study examined the longitudinal relationship of body mass index (BMI) and waist circumference with the incidence and persistence of MDD over 2-year and 6-year periods.
Method: Data were sourced from the Netherlands Study of Depression and Anxiety. MDD was established with Composite International Diagnostic Interviews. The relationship of BMI and waist circumference with the development of depression two and six years later were estimated in the subsample with no current psychopathology at baseline. Associations with the persistence of depression was estimated in the subsample with current MDD.
Results: Higher BMI at baseline, but not waist circumference, slightly increased the odds of the development of MDD after two years (odds ratio (OR) per standard deviation increase: 1.11; p=0.03), This relationship was not significant after adjustment for health and lifestyle variables. Conversely, over a 6-year period both BMI and waist circumference moderately increased the odds of developing MDD even after adjustment (OR:1.17; p=0.05, OR:1.20; p=0.05). Persistence of MDD in currently depressed subjects, is not related with BMI or waist circumference (adjusted OR:0.93; p=0.2, OR:0.91; p=0.15).
Limitations: Development of depression may differ in participants lost to follow-up.
Conclusion: Over a 6 year period, patients with higher BMI show a slightly increased risk of development of depression. However, in depressed patients there is no relationship between BMI and the persistence of depression.
(Copyright © 2016 Elsevier B.V. All rights reserved.)
تواريخ الأحداث: Date Created: 20160401 Date Completed: 20171120 Latest Revision: 20220317
رمز التحديث: 20231215
DOI: 10.1016/j.jad.2016.03.032
PMID: 27031289
قاعدة البيانات: MEDLINE
الوصف
تدمد:1573-2517
DOI:10.1016/j.jad.2016.03.032