دورية أكاديمية

[THE MOLECULAR GENETIC CHARACTERISTIC OF SPECIES CONTENT OF SALIVA AND GINGIVAL RECESS UNDER PERIODONTITIS].

التفاصيل البيبلوغرافية
العنوان: [THE MOLECULAR GENETIC CHARACTERISTIC OF SPECIES CONTENT OF SALIVA AND GINGIVAL RECESS UNDER PERIODONTITIS].
المؤلفون: Tamarova ER, Baimiev AKh, Shvetz KY, Mavzyutov AR
المصدر: Klinicheskaia laboratornaia diagnostika [Klin Lab Diagn] 2015 Dec; Vol. 60 (12), pp. 56-9.
نوع المنشور: Journal Article
اللغة: Russian
بيانات الدورية: Publisher: Meditsina Country of Publication: Russia (Federation) NLM ID: 9432021 Publication Model: Print Cited Medium: Print ISSN: 0869-2084 (Print) Linking ISSN: 08692084 NLM ISO Abbreviation: Klin Lab Diagn Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Moskva : "Meditsina", 1992-
مواضيع طبية MeSH: DNA, Bacterial/*genetics , Periodontal Pocket/*diagnosis , Periodontitis/*diagnosis , Porphyromonas gingivalis/*genetics , Streptococcus/*genetics , Treponema denticola/*genetics, Adolescent ; Adult ; Aged ; Anesthetics, Local ; Anti-Bacterial Agents/therapeutic use ; Case-Control Studies ; Female ; Gingiva/microbiology ; Humans ; Lidocaine ; Lincomycin/therapeutic use ; Male ; Middle Aged ; Periodontal Pocket/drug therapy ; Periodontal Pocket/microbiology ; Periodontal Pocket/pathology ; Periodontitis/drug therapy ; Periodontitis/microbiology ; Periodontitis/pathology ; Polymerase Chain Reaction/methods ; Porphyromonas gingivalis/classification ; Porphyromonas gingivalis/isolation & purification ; Saliva/microbiology ; Streptococcus/classification ; Streptococcus/isolation & purification ; Treponema denticola/classification ; Treponema denticola/isolation & purification
مستخلص: The examination was carried out of samplings of 110 patients with periodontitis (observation group) and 60 patients without pathology of periodont (comparison group). The polymerase chain reaction was used to analyze samples of saliva and contents of periodontal recesses for detecting species-specific DNA fragments of Porphymmonas gigngivalis, Streptococcus macacae, S. mutans, S. oralis, S. salivarius, S. sangis, S. sobrinus, Treponema denticola. In patients with periodontitis S. mutans, S. oralis S. sobrinus were reliably more often detected in the content of periodontal recesses and S. mutans, S. sobrinus i in saliva. In the observation group the rate of detection of association S. mutans--S. oralis--S. sangis--S. sobrinus was significantly exceeded (up to 15.6%, X2 = 9.1, p = 0.004). In ten days of effective treatment of periodontitis reliable decreastng of rate of detection of S. wasoralis, S. sobrinus was observed in contents of periodontal recesses but not in of saliva. The detection of S.sobrinus using technique of polymerase chain reaction in contents of periodontal recesses and/or saliva of patients with periodontitis has a diagnostic value. The detection of S.sobrinus in contents of periodontal recesses is significant both in monoculture and in association S. mutans--S. oralis--S. sangis--S.sobrinus. The absence of S. sobrinus in contents of periodontal recesses testifies effectiveness of treatment of main disease (periodontitis).
المشرفين على المادة: 0 (Anesthetics, Local)
0 (Anti-Bacterial Agents)
0 (DNA, Bacterial)
98PI200987 (Lidocaine)
BOD072YW0F (Lincomycin)
تواريخ الأحداث: Date Created: 20160402 Date Completed: 20160419 Latest Revision: 20201209
رمز التحديث: 20240628
PMID: 27032255
قاعدة البيانات: MEDLINE