دورية أكاديمية
C8-T1 Radiculopathy Due to an Intradural Extramedullary Metastasis of a Pancreatic Neuroendocrine Tumor: Case Report and Review of the Literature.
| العنوان: | C8-T1 Radiculopathy Due to an Intradural Extramedullary Metastasis of a Pancreatic Neuroendocrine Tumor: Case Report and Review of the Literature. |
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| المؤلفون: | Cabezas-Camarero S; From the Departments of *Medical Oncology and †Radiology, ‡Pathology Laboratory, and §Department of Neurosurgery, Hospital Universitario Clínico San Carlos, Madrid, Spain. Centre Affiliated to the 'Red Temática de Investigación Cooperativa (RD12/0036/006)', Instituto Carlos III, Spanish Ministry of Economy and Competitivity., Sastre J, Polidura MC, Gómez-Ruíz MN, Subhi-Issa I, Alonso Lera P, Paredes BG, Díaz-Rubio E |
| المصدر: | Pancreas [Pancreas] 2016 May-Jun; Vol. 45 (5), pp. 772-9. |
| نوع المنشور: | Case Reports; Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 8608542 Publication Model: Print Cited Medium: Internet ISSN: 1536-4828 (Electronic) Linking ISSN: 08853177 NLM ISO Abbreviation: Pancreas Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Hagerstown, MD : Lippincott Williams & Wilkins Original Publication: [New York, N.Y.] : Raven Press, [c1986- |
| مواضيع طبية MeSH: | Neuroendocrine Tumors/*diagnostic imaging , Pancreatic Neoplasms/*diagnostic imaging , Radiculopathy/*diagnostic imaging , Spinal Cord Compression/*diagnostic imaging , Spinal Cord Neoplasms/*diagnostic imaging, Aged, 80 and over ; Fatal Outcome ; Humans ; Magnetic Resonance Imaging/methods ; Male ; Neuroendocrine Tumors/pathology ; Pancreatic Neoplasms/pathology ; Positron Emission Tomography Computed Tomography/methods ; Radiculopathy/etiology ; Spinal Cord Compression/etiology ; Spinal Cord Neoplasms/complications ; Spinal Cord Neoplasms/secondary |
| مستخلص: | Pancreatic neuroendocrine tumors (pNETs) are usually well-to-moderately differentiated neuroendocrine tumors (NETs) that most often metastasize to the liver and lymph nodes with other locations being uncommon. We present a case of intradural pNET metastasis and conduct a review of the literature. Forty-five cases, including the case presently reported, of spinal cord compression due to well-differentiated NETs were found: carcinoid (80%), pNET (13.3%), and NETs of unknown primary (6.7%). Seventy-eight percent of cases consisted of extradural compressions from vertebral bone metastases, whereas there were only 5 cases of intradural extramedullary spinal cord compression. Most cases were managed with surgery and/or radiotherapy with a good clinical outcome in the majority. We report the first case of a pNET intradural extramedullary metastasis and conduct the largest review to date of an infrequent complication of well-differentiated NETs such as malignant spinal cord compression. Aggressive local treatment is warranted in most cases because it usually achieves neurologic improvement and symptomatic relief in patients who may still have a long life expectancy. |
| تواريخ الأحداث: | Date Created: 20160415 Date Completed: 20170111 Latest Revision: 20170112 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1097/MPA.0000000000000515 |
| PMID: | 27077714 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1536-4828 |
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| DOI: | 10.1097/MPA.0000000000000515 |