دورية أكاديمية
أعرض في EDS

Serratia marcescens resistance profile and its susceptibility to photodynamic antimicrobial chemotherapy.

التفاصيل البيبلوغرافية
العنوان: Serratia marcescens resistance profile and its susceptibility to photodynamic antimicrobial chemotherapy.
المؤلفون: Parente TM; Biotechnology Post-Graduate Program, Federal University of Ceara, Comandante Mauricélio, Rocha Pontes Street, 100, Sobral, CE 62.042-280 Brazil., Rebouças Ede L; Biotechnology Post-Graduate Program, Federal University of Ceara, Comandante Mauricélio, Rocha Pontes Street, 100, Sobral, CE 62.042-280 Brazil., Santos VC; Brazilian Agricultural Research Corporation-EMBRAPA Goats and Sheep, Fazenda Três Lagoas, Sobral/Groaíras Road, Km 4, Sobral, CE 62010-970 Brazil., Barbosa FC; College of Dentistry, Federal University of Ceara, Coronel Estanislau Frota Street s/n, Sobral, CE 62010-560, Brazil., Zanin IC; College of Dentistry, Federal University of Ceara, Coronel Estanislau Frota Street s/n, Sobral, CE 62010-560, Brazil. Electronic address: irianaz@yahoo.com.br.
المصدر: Photodiagnosis and photodynamic therapy [Photodiagnosis Photodyn Ther] 2016 Jun; Vol. 14, pp. 185-90. Date of Electronic Publication: 2016 Apr 13.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101226123 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-1597 (Electronic) Linking ISSN: 15721000 NLM ISO Abbreviation: Photodiagnosis Photodyn Ther Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Amsterdam ; Boston : Elsevier, c2004-
مواضيع طبية MeSH: Photochemotherapy* , Serratia marcescens*, Anti-Infective Agents/*therapeutic use , Cross Infection/*therapy, Drug Resistance, Microbial ; Humans ; Photosensitizing Agents/pharmacology
مستخلص: Background: Some authors have reported the antimicrobial action of photodynamic antimicrobial chemotherapy (PACT) on bacteria related to nosocomial infections but there are few studies evaluating PACT on Serratia marcescens grown as planktonic cultures or as biofilms. The purpose of this study was to analyze the S. marcescens resistance profile and its susceptibility to PACT.
Methods: Initially, 55 S. marcescens strains isolated from environmental, oral and extra-oral infections were tested by antimicrobial resistance to cefotaxime (CTX), imipenem (IPM), ciprofloxacin (CIP), tobramycin (TOB) and doxycycline (DOX) using E-test(®). Following, isolates grown as planktonic cultures or biofilms were submitted to PACT using the association of a light-emitting diode and toluidine blue (TBO). The E-test(®) results demonstrated intermediated sensitive strains to CTX, IMP, TOB, and DOX; and resistant strains to CTX, TOB, DOX and CIP. Also, CTX and IMP demonstrated variation when CLSI 2007 and CLSI 2015 were compared.
Results: Planktonic cultures and biofilms submitted to PACT demonstrated counts varying from 10(11) to 10(7) for planktonic cultures and 10(10) to 10(7) for biofilms. There were no statistical differences in the results when planktonic cultures and biofilms were compared.
Conclusions: Increase in the profile of S. marcescens resistance was observed when CLSI 2007 and CLSI 2015 were compared. Also, IMP remains as the drug with lower rate of resistance. Additionally, both S. marcescens planktonic cultures and early biofilms are susceptible to PACT under tested conditions.
(Copyright © 2016 Elsevier B.V. All rights reserved.)
فهرسة مساهمة: Keywords: Antibiotic resistance; Biofilms; Infection disease; Photodynamic antimicrobial chemotherapy; Serratia marcescens
المشرفين على المادة: 0 (Anti-Infective Agents)
0 (Photosensitizing Agents)
تواريخ الأحداث: Date Created: 20160418 Date Completed: 20170517 Latest Revision: 20170517
رمز التحديث: 20240628
DOI: 10.1016/j.pdpdt.2016.04.007
PMID: 27085794
قاعدة البيانات: MEDLINE
الوصف
تدمد:1873-1597
DOI:10.1016/j.pdpdt.2016.04.007