دورية أكاديمية
أعرض في EDS

Optimizing contrast media application in coronary CT angiography at lower tube voltage: Evaluation in a circulation phantom and sixty patients.

التفاصيل البيبلوغرافية
العنوان: Optimizing contrast media application in coronary CT angiography at lower tube voltage: Evaluation in a circulation phantom and sixty patients.
المؤلفون: Kok M; Department of Radiology, Maastricht University Medical Center, The Netherlands; CARIM, School for Cardiovascular Diseases, Maastricht University Medical Center, Maastricht, The Netherlands. Electronic address: madeleinekok1@gmail.com., Mihl C; Department of Radiology, Maastricht University Medical Center, The Netherlands; CARIM, School for Cardiovascular Diseases, Maastricht University Medical Center, Maastricht, The Netherlands. Electronic address: caspermihl@gmail.com., Hendriks BM; Department of Radiology, Maastricht University Medical Center, The Netherlands. Electronic address: babs.hendriks@mumc.nl., Altintas S; CARIM, School for Cardiovascular Diseases, Maastricht University Medical Center, Maastricht, The Netherlands; Department of Cardiology, Maastricht University Medical Center, The Netherlands. Electronic address: s.altintas@mumc.nl., Kietselaer BL; Department of Radiology, Maastricht University Medical Center, The Netherlands; CARIM, School for Cardiovascular Diseases, Maastricht University Medical Center, Maastricht, The Netherlands; Department of Cardiology, Maastricht University Medical Center, The Netherlands. Electronic address: b.kietselaer@mumc.nl., Wildberger JE; Department of Radiology, Maastricht University Medical Center, The Netherlands; CARIM, School for Cardiovascular Diseases, Maastricht University Medical Center, Maastricht, The Netherlands. Electronic address: j.wildberger@mumc.nl., Das M; Department of Radiology, Maastricht University Medical Center, The Netherlands; CARIM, School for Cardiovascular Diseases, Maastricht University Medical Center, Maastricht, The Netherlands. Electronic address: m.das@mumc.nl.
المصدر: European journal of radiology [Eur J Radiol] 2016 Jun; Vol. 85 (6), pp. 1068-74. Date of Electronic Publication: 2016 Mar 22.
نوع المنشور: Comparative Study; Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Science Ireland Ltd Country of Publication: Ireland NLM ID: 8106411 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7727 (Electronic) Linking ISSN: 0720048X NLM ISO Abbreviation: Eur J Radiol Subsets: MEDLINE
أسماء مطبوعة: Publication: Limerick : Elsevier Science Ireland Ltd
Original Publication: Stuttgart ; New York : Thieme, [c1981-
مواضيع طبية MeSH: Phantoms, Imaging*, Computed Tomography Angiography/*methods , Contrast Media/*administration & dosage , Coronary Angiography/*methods , Iohexol/*analogs & derivatives, Adult ; Aged ; Aorta/diagnostic imaging ; Blood Pressure/physiology ; Heart Rate/physiology ; Humans ; Iliac Artery/diagnostic imaging ; Iodine/administration & dosage ; Iohexol/administration & dosage ; Middle Aged ; Multidetector Computed Tomography/methods ; Radiation Dosage ; Radiographic Image Enhancement/methods ; Renal Artery/diagnostic imaging ; Tomography, Spiral Computed/methods
مستخلص: Purpose: The purpose was to investigate optimal contrast media (CM) injection parameters for lower kVp settings, whilst maintaining diagnostic attenuation levels.
Methods and Materials: First, a circulation phantom with physiological parameters (BP 120/80mmHg, HR 60bpm) was used. A fixed CM injection protocol was used for each kVp setting (300mgI/ml [Iopromide], volume=45ml, flow rate=6.0ml/s, iodine delivery rate [IDR]=1.8gI/s, iodine load=13.5gI; at 120, 100, 80 and 70kVp). Then, IDR was decreased by steps of 0.2gI/s for each kVp setting, until diagnostically insufficient attenuation values were reached (<325HU). In order to keep injection time constant (7.5s), total iodine load (TIL) was reduced accordingly. Second, clinical applicability at 120 and 100kVp was evaluated in patients (n=60) referred for coronary CT angiography. A standard and reduced (12% less) CM protocol was used based on weight classes and scan duration ('high-pitch': 1s; 'adaptive sequence' and 'helical': 7s). Attenuation levels of the coronary arteries were measured and compared between protocols.
Results: Using a fixed CM injection at each kVp level resulted in the following HU values: 335HU±31 (120kVp); 425HU±30 (100kVp); 587HU±29 (80kVp); 666HU±27 (70kVp). Keeping diagnostic enhancement levels (353HU±28) CM could be reduced as follows: 12% for 100kVp; 45% for 80kVp and 56% for 70kVp. Diagnostic enhancement levels could be reproduced with concurrent CM reduction (-12% at 100kV) in the clinical setting (382HU±35).
Conclusion: CM injection parameters can be substantially reduced at low kVp settings (up to 56% at 70kVp), whilst maintaining diagnostic attenuation levels. This may play an important role in CT imaging of the coronary arteries as well as cerebral and peripheral circulations in the future.
(Copyright © 2016. Published by Elsevier Ireland Ltd.)
فهرسة مساهمة: Keywords: Contrast media; Multidetector-row computed tomography; Tube voltage
المشرفين على المادة: 0 (Contrast Media)
4419T9MX03 (Iohexol)
712BAC33MZ (iopromide)
9679TC07X4 (Iodine)
تواريخ الأحداث: Date Created: 20160511 Date Completed: 20161213 Latest Revision: 20181202
رمز التحديث: 20231215
DOI: 10.1016/j.ejrad.2016.03.022
PMID: 27161054
قاعدة البيانات: MEDLINE
الوصف
تدمد:1872-7727
DOI:10.1016/j.ejrad.2016.03.022