دورية أكاديمية
أعرض في EDS

Initiation and completion rates for latent tuberculosis infection treatment: a systematic review.

التفاصيل البيبلوغرافية
العنوان: Initiation and completion rates for latent tuberculosis infection treatment: a systematic review.
المؤلفون: Sandgren A; Former Surveillance and Response Section, European Centre for Disease Prevention and Control (ECDC), Stockholm, 171 65, Sweden., Vonk Noordegraaf-Schouten M; Pallas, Health Research and Consultancy B.V., Rotterdam, 3001, The Netherlands., van Kessel F; Pallas, Health Research and Consultancy B.V., Rotterdam, 3001, The Netherlands., Stuurman A; Pallas, Health Research and Consultancy B.V., Rotterdam, 3001, The Netherlands., Oordt-Speets A; Pallas, Health Research and Consultancy B.V., Rotterdam, 3001, The Netherlands., van der Werf MJ; Tomtebodavägen 11a, 171 65, Solna, Sweden. marieke.vanderwerf@ecdc.europa.eu.
المصدر: BMC infectious diseases [BMC Infect Dis] 2016 May 17; Vol. 16, pp. 204. Date of Electronic Publication: 2016 May 17.
نوع المنشور: Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Systematic Review
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100968551 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2334 (Electronic) Linking ISSN: 14712334 NLM ISO Abbreviation: BMC Infect Dis Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central, [2001-
مواضيع طبية MeSH: Latent Tuberculosis/*drug therapy, Emigrants and Immigrants ; HIV Infections/microbiology ; Health Personnel ; Ill-Housed Persons ; Humans ; Latent Tuberculosis/diagnosis ; Medication Adherence/statistics & numerical data
مستخلص: Background: Control of latent tuberculosis infection (LTBI) is an important step towards tuberculosis elimination. Preventive treatment will prevent the development of disease in most cases diagnosed with LTBI. However, low initiation and completion rates affect the effectiveness of preventive treatment. The objective was to systematically review data on initiation rates and completion rates for LTBI treatment regimens in the general population and specific populations with LTBI.
Methods: A systematic review of the literature (PubMed, Embase) published up to February 2014 was performed.
Results: Forty-five studies on initiation rates and 83 studies on completion rates of LTBI treatment were found. These studies provided initiation rates (IR) and completion rates (CR) in people with LTBI among the general population (IR 26-99 %, CR 39-96 %), case contacts (IR 40-95 %, CR 48-82 %), healthcare workers (IR 47-98 %, CR 17-79 %), the homeless (IR 34-90 %, CR 23-71 %), people who inject drugs (IR 52-91 %, CR 38-89 %), HIV-infected individuals (IR 67-92 %, CR 55-95 %), inmates (IR 7-90 %, CR 4-100 %), immigrants (IR 23-97 %, CR 7-86 %), and patients with comorbidities (IR 82-93 %, CR 75-92 %). Generally, completion rates were higher for short than for long LTBI treatment regimens.
Conclusion: Initiation and completion rates for LTBI treatment regimens were frequently suboptimal and varied greatly within and across different populations.
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فهرسة مساهمة: Keywords: Latent tuberculosis; Risk groups; Treatment completion; Treatment initiation; Tuberculosis
تواريخ الأحداث: Date Created: 20160518 Date Completed: 20170619 Latest Revision: 20240325
رمز التحديث: 20240325
مُعرف محوري في PubMed: PMC4869320
DOI: 10.1186/s12879-016-1550-y
PMID: 27184748
قاعدة البيانات: MEDLINE
الوصف
تدمد:1471-2334
DOI:10.1186/s12879-016-1550-y