دورية أكاديمية
Six-Year Graft Survival After Partial Pancreas Heterotopic Auto-Transplantation: A Case Report.
| العنوان: | Six-Year Graft Survival After Partial Pancreas Heterotopic Auto-Transplantation: A Case Report. |
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| المؤلفون: | Kobayashi T; Division of Digestive and General Surgery, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan. Electronic address: kobataka@med.niigata-u.ac.jp., Miura K; Division of Digestive and General Surgery, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan., Ishikawa H; Division of Digestive and General Surgery, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan., Soma D; Division of Digestive and General Surgery, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan., Zhang Z; Division of Digestive and General Surgery, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan., Yuza K; Division of Digestive and General Surgery, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan., Hirose Y; Division of Digestive and General Surgery, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan., Takizawa K; Division of Digestive and General Surgery, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan., Nagahashi M; Division of Digestive and General Surgery, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan., Sakata J; Division of Digestive and General Surgery, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan., Kameyama H; Division of Digestive and General Surgery, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan., Kosugi SI; Division of Digestive and General Surgery, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan., Tada T; Department of Surgery, Tachikawa General Hospital, Nagaoka, Japan., Hirukawa H; Department of Surgery, Tachikawa General Hospital, Nagaoka, Japan., Wakai T; Division of Digestive and General Surgery, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan. |
| المصدر: | Transplantation proceedings [Transplant Proc] 2016 Apr; Vol. 48 (3), pp. 988-90. |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Science Inc Country of Publication: United States NLM ID: 0243532 Publication Model: Print Cited Medium: Internet ISSN: 1873-2623 (Electronic) Linking ISSN: 00411345 NLM ISO Abbreviation: Transplant Proc Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: New York, N.Y. : Elsevier Science Inc. Original Publication: New York Stratton. |
| مواضيع طبية MeSH: | Graft Survival* , Pancreas Transplantation*, Pancreatic Neoplasms/*surgery, Female ; Follow-Up Studies ; Humans ; Middle Aged ; Transplantation, Heterotopic ; Pancreatic Neoplasms |
| مستخلص: | Background: Long-term graft survival of partial pancreas auto-transplantation after total pancreatectomy has not been clarified. The clinical implications of repeat completion pancreatectomy for locally recurrent pancreatic carcinoma in the remnant pancreas after initial pancreatectomy also have not been clarified. Methods: We have previously reported a 61-year-old woman presenting with re-sectable carcinoma of the remnant pancreas at 3 years after undergoing a pylorus-preserving pancreaticoduodenectomy for invasive ductal carcinoma of the pancreas head. We also performed distal pancreas auto-transplantation with the use of a part of the resected pancreas to preserve endocrine function. Results: The patient was discharged at 20 days after surgery without any complications. She had been followed regularly in our outpatient clinic. She had been treated with S-1 as adjuvant chemotherapy; 72 months after the completion total pancreatectomy with distal partial pancreas auto-transplantation, the patient was alive without any evidence of the pancreatic carcinoma recurrence. The pancreas graft was still functioning with a blood glucose level of 112 mg/dL, HbA1C of 6.7%, and serum C-peptide of 1.2 ng/mL; and urinary C-peptide was 11.6 μg/d. Conclusions: Our patient demonstrated that repeated pancreatectomies can provide a chance for survival after a locally recurrent pancreatic carcinoma if the disease is limited to the remnant pancreas. An additional partial pancreas auto-transplantation was successfully performed to preserve endocrine function. However, the indications for pancreas auto-transplantation should be decided carefully in the context of pancreatic carcinoma recurrence. (Copyright © 2016 Elsevier Inc. All rights reserved.) |
| تواريخ الأحداث: | Date Created: 20160529 Date Completed: 20161223 Latest Revision: 20231213 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1016/j.transproceed.2016.01.030 |
| PMID: | 27234786 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1873-2623 |
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| DOI: | 10.1016/j.transproceed.2016.01.030 |