دورية أكاديمية
أعرض في EDS

Interventions for improving adherence to treatment for latent tuberculosis infection: a systematic review.

التفاصيل البيبلوغرافية
العنوان: Interventions for improving adherence to treatment for latent tuberculosis infection: a systematic review.
المؤلفون: Stuurman AL; Pallas health research and consultancy BV, Rotterdam, The Netherlands., Vonk Noordegraaf-Schouten M; Pallas health research and consultancy BV, Rotterdam, The Netherlands., van Kessel F; Pallas health research and consultancy BV, Rotterdam, The Netherlands., Oordt-Speets AM; Pallas health research and consultancy BV, Rotterdam, The Netherlands., Sandgren A; European Centre for Disease Prevention and Control (ECDC), Tomtebodavägen 11a, Solna, 171 65, Sweden., van der Werf MJ; European Centre for Disease Prevention and Control (ECDC), Tomtebodavägen 11a, Solna, 171 65, Sweden. marieke.vanderwerf@ecdc.europa.eu.
المصدر: BMC infectious diseases [BMC Infect Dis] 2016 Jun 08; Vol. 16, pp. 257. Date of Electronic Publication: 2016 Jun 08.
نوع المنشور: Journal Article; Review; Systematic Review
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100968551 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2334 (Electronic) Linking ISSN: 14712334 NLM ISO Abbreviation: BMC Infect Dis Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central, [2001-
مواضيع طبية MeSH: Patient Compliance*, Antitubercular Agents/*therapeutic use , Latent Tuberculosis/*drug therapy, Antitubercular Agents/administration & dosage ; Directly Observed Therapy ; Humans ; Latent Tuberculosis/prevention & control ; Motivation ; Prospective Studies
مستخلص: Background: Latent tuberculosis infection (LTBI) control relies on high initiation and completion rates of preventive treatment to preclude progression to tuberculosis disease. Specific interventions may improve initiation and completion rates. The objective was to systematically review data on determinants of initiation, adherence and completion of LTBI treatment, and on interventions to improve initiation and completion.
Methods: A systematic review of the literature (PubMed, Embase) published up to February 2014 was performed. Relevant prospective intervention studies were assessed using GRADE.
Results: Sixty-two articles reporting on determinants of treatment initiation and completion were included and 23 articles on interventions. Determinants of LTBI treatment completion include shorter treatment regimen and directly observed treatment (DOT, positive association), adverse events and alcohol use (negative association), and specific populations with LTBI (both positive and negative associations). A positive effect on completion was noted in intervention studies that used short regimens and social interventions; mixed results were found for intervention studies that used DOT or incentives.
Conclusion: LTBI treatment completion can be improved by using shorter regimens and social interventions. Specific needs of the different populations with LTBI should be addressed taking into consideration the setting and condition in which the LTBI treatment programme is implemented.
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فهرسة مساهمة: Keywords: Latent tuberculosis; Risk groups; Treatment adherence; Treatment completion; Treatment initiation; Tuberculosis
المشرفين على المادة: 0 (Antitubercular Agents)
تواريخ الأحداث: Date Created: 20160609 Date Completed: 20170703 Latest Revision: 20181202
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC4897858
DOI: 10.1186/s12879-016-1549-4
PMID: 27268103
قاعدة البيانات: MEDLINE
الوصف
تدمد:1471-2334
DOI:10.1186/s12879-016-1549-4