دورية أكاديمية
Coenuriasis in a spectacled langur (Presbytis obscura): praziquantel treatment and the antibody response to cyst antigens.
| العنوان: | Coenuriasis in a spectacled langur (Presbytis obscura): praziquantel treatment and the antibody response to cyst antigens. |
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| المؤلفون: | Price TC; Baylor College of Medicine, Houston, Texas., Dresden MH, Alvarado T, Flanagan J, Chappell CL |
| المصدر: | The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 1989 May; Vol. 40 (5), pp. 514-20. |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: American Society of Tropical Medicine and Hygiene Country of Publication: United States NLM ID: 0370507 Publication Model: Print Cited Medium: Print ISSN: 0002-9637 (Print) Linking ISSN: 00029637 NLM ISO Abbreviation: Am J Trop Med Hyg Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Northbrook, IL : American Society of Tropical Medicine and Hygiene Original Publication: Baltimore. |
| مواضيع طبية MeSH: | Cercopithecidae/*parasitology , Cestode Infections/*veterinary , Monkey Diseases/*drug therapy , Praziquantel/*therapeutic use, Animals ; Antibodies, Helminth/biosynthesis ; Antigens, Helminth/immunology ; Cestode Infections/drug therapy ; Cestode Infections/immunology ; Electrophoresis, Polyacrylamide Gel ; Enzyme-Linked Immunosorbent Assay ; Immunoblotting ; Immunoglobulin G/biosynthesis ; Immunoglobulin M/biosynthesis ; Male ; Monkey Diseases/immunology ; Taenia/immunology ; Tomography, X-Ray Computed/veterinary |
| مستخلص: | A diagnosis of coenuriasis was made in a spectacled langur raised in captivity. Multiple cysts removed from the subcutaneous tissues and later from the abdominal cavity were identified as coenuri, typical of the genus Taenia. Post-surgical treatment of the remaining cysts with praziquantel was assessed with whole body computerized tomography (CT). CT at 6 weeks post-treatment revealed a reduction in size and increased calcification of abdominal cysts as compared to pretreatment CT. Cyst fluid antigens in ELISA assays showed a high titer (1:5, 120) IgG response in the langur serum, while no IgM response could be detected. No decrease in IgG titer was seen 6 weeks after treatment. Immunoblot analyses identified several parasite-specific antigens with apparent molecular weights of greater than 92.5 (3 bands), 88, 41, 37, and 34 kDa. |
| المشرفين على المادة: | 0 (Antibodies, Helminth) 0 (Antigens, Helminth) 0 (Immunoglobulin G) 0 (Immunoglobulin M) 6490C9U457 (Praziquantel) |
| تواريخ الأحداث: | Date Created: 19890501 Date Completed: 19890703 Latest Revision: 20190516 |
| رمز التحديث: | 20231215 |
| DOI: | 10.4269/ajtmh.1989.40.514 |
| PMID: | 2729508 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0002-9637 |
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| DOI: | 10.4269/ajtmh.1989.40.514 |