دورية أكاديمية
أعرض في EDS

Ultrasound-Guided Percutaneous Ethanol Injection Protocol to Treat Solid and Mixed Thyroid Nodules.

التفاصيل البيبلوغرافية
العنوان: Ultrasound-Guided Percutaneous Ethanol Injection Protocol to Treat Solid and Mixed Thyroid Nodules.
المؤلفون: Felício JS; Endocrinology Division, University Hospital João de Barros Barreto, Federal University of Pará , Belém , Brazil., Conceição AM; Endocrinology Division, University Hospital João de Barros Barreto, Federal University of Pará , Belém , Brazil., Santos FM; Endocrinology Division, University Hospital João de Barros Barreto, Federal University of Pará , Belém , Brazil., Sato MM; Endocrinology Division, University Hospital João de Barros Barreto, Federal University of Pará , Belém , Brazil., Bastos Fde A; Endocrinology Division, University Hospital João de Barros Barreto, Federal University of Pará , Belém , Brazil., Braga de Souza AC; Endocrinology Division, University Hospital João de Barros Barreto, Federal University of Pará , Belém , Brazil., Koury CC; Endocrinology Division, University Hospital João de Barros Barreto, Federal University of Pará , Belém , Brazil., Neto JF; Endocrinology Division, University Hospital João de Barros Barreto, Federal University of Pará , Belém , Brazil., Cunha de Melo FT; Endocrinology Division, University Hospital João de Barros Barreto, Federal University of Pará , Belém , Brazil., Carvalho CT; Endocrinology Division, University Hospital João de Barros Barreto, Federal University of Pará , Belém , Brazil., Arbage TP; Endocrinology Division, University Hospital João de Barros Barreto, Federal University of Pará , Belém , Brazil., Junior AB; Endocrinology Division, University Hospital João de Barros Barreto, Federal University of Pará , Belém , Brazil., de Rider Brito HA; Endocrinology Division, University Hospital João de Barros Barreto, Federal University of Pará , Belém , Brazil., Júnior MO; Endocrinology Division, University Hospital João de Barros Barreto, Federal University of Pará , Belém , Brazil., Resende Fde S; Endocrinology Division, University Hospital João de Barros Barreto, Federal University of Pará , Belém , Brazil., Peixoto AS; Endocrinology Division, University Hospital João de Barros Barreto, Federal University of Pará , Belém , Brazil., Felício KM; Endocrinology Division, University Hospital João de Barros Barreto, Federal University of Pará , Belém , Brazil.
المصدر: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2016 Jun 06; Vol. 7, pp. 52. Date of Electronic Publication: 2016 Jun 06 (Print Publication: 2016).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: [Lausanne : Frontiers Research Foundation]
مستخلص: Context: Ultrasound (US)-guided percutaneous ethanol injection (PEI) has been proposed for treatment of benign thyroid nodules (TNs). However, there is no consensus for the optimal amount of ethanol injection, number of applications, and time to re-evaluation in order to achieve maximum volume reduction with minimum adverse effects.
Objective: The purpose of the present study was to analyze the effectiveness of an US-guided PEI protocol to treat solid and mixed TNs based on a new target outcome.
Patients and Methods: We performed a prospective study evaluating the results of PEI in 52 patients with benign solid and mixed TNs. The ethanol dose was fixed in 30% of the nodular volume per session. Patients returned 1 month after each session for US re-evaluation. Therapeutic success was defined as volume reduction of at least 30% associated with disappearance of clinical symptoms and a complete esthetic satisfaction reported by the patient.
Results: We performed a mean of 2.8 ± 1.9 PEI sessions, with an average total volume of ethanol injected of 9.1 ± 10.3 ml, and a follow-up time of 10.0 ± 8.7 months. There was a reduction of at least 50% of the initial nodular volume in 33 patients (63.5%). In 11 patients (21.2%), the reduction did not reach 50% (mean reduction of 31 ± 11%), but 6 of them reported esthetically satisfactory results and treatment was stopped. Our therapeutic success rate considering the patients with esthetic improvement was 75%. There were no severe complications.
Conclusion: Our protocol is effective and safe to treat solid and mixed benign TNs based on our established outcome.
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فهرسة مساهمة: Keywords: US-guided; alcoholization; nodule volume reduction; percutaneous ethanol injection; thyroid nodules
تواريخ الأحداث: Date Created: 20160705 Date Completed: 20160704 Latest Revision: 20181113
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC4893597
DOI: 10.3389/fendo.2016.00052
PMID: 27375551
قاعدة البيانات: MEDLINE
الوصف
تدمد:1664-2392
DOI:10.3389/fendo.2016.00052