دورية أكاديمية
أعرض في EDS

Markers associated with heading and aftermath heading in perennial ryegrass full-sib families.

التفاصيل البيبلوغرافية
العنوان: Markers associated with heading and aftermath heading in perennial ryegrass full-sib families.
المؤلفون: Arojju SK; Teagasc, Crop Science Department, Oak Park, Carlow, Ireland.; Department of Botany, Trinity College Dublin, Dublin 2, Dublin, Ireland., Barth S; Teagasc, Crop Science Department, Oak Park, Carlow, Ireland., Milbourne D; Teagasc, Crop Science Department, Oak Park, Carlow, Ireland., Conaghan P; Teagasc, Grassland Science Research Department, Animal and Grassland Research and Innovation Centre, Oak Park, Carlow, Ireland., Velmurugan J; Teagasc, Crop Science Department, Oak Park, Carlow, Ireland., Hodkinson TR; Department of Botany, Trinity College Dublin, Dublin 2, Dublin, Ireland., Byrne SL; Teagasc, Crop Science Department, Oak Park, Carlow, Ireland. stephen.byrne@teagasc.ie.
المصدر: BMC plant biology [BMC Plant Biol] 2016 Jul 16; Vol. 16 (1), pp. 160. Date of Electronic Publication: 2016 Jul 16.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100967807 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2229 (Electronic) Linking ISSN: 14712229 NLM ISO Abbreviation: BMC Plant Biol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central, [2001-
مواضيع طبية MeSH: Lolium/*genetics, Alleles ; Chromosome Mapping ; Genetic Markers ; Genetic Variation ; Genome, Plant ; Genome-Wide Association Study ; Genomics ; Genotype ; Lolium/classification ; Phylogeny
مستخلص: Background: Heading and aftermath heading are important traits in perennial ryegrass because they impact forage quality. So far, genome-wide association analyses in this major forage species have only identified a small number of genetic variants associated with heading date that overall explained little of the variation. Some possible reasons include rare alleles with large phenotypic affects, allelic heterogeneity, or insufficient marker density. We established a genome-wide association panel with multiple genotypes from multiple full-sib families. This ensured alleles were present at the frequency needed to have sufficient statistical power to identify associations. We genotyped the panel via partial genome sequencing and performed genome-wide association analyses with multi-year phenotype data collected for heading date, and aftermath heading.
Results: Genome wide association using a mixed linear model failed to identify any variants significantly associated with heading date or aftermath heading. Our failure to identify associations for these traits is likely due to the extremely low linkage disequilibrium we observed in this population. However, using single marker analysis within each full-sib family we could identify markers and genomic regions associated with heading and aftermath heading. Using the ryegrass genome we identified putative orthologs of key heading genes, some of which were located in regions of marker-trait associations.
Conclusion: Given the very low levels of LD, genome wide association studies in perennial ryegrass populations are going to require very high SNP densities. Single marker analysis within full-sibs enabled us to identify significant marker-trait associations. One of these markers anchored proximal to a putative ortholog of TFL1, homologues of which have been shown to play a key role in continuous heading of some members of the rose family, Rosaceae.
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فهرسة مساهمة: Keywords: Aftermath heading; Flowering; Genome wide association; Heading; Lolium perenne; Perennial ryegrass; Single marker analysis
المشرفين على المادة: 0 (Genetic Markers)
تواريخ الأحداث: Date Created: 20160717 Date Completed: 20170818 Latest Revision: 20231105
رمز التحديث: 20231105
مُعرف محوري في PubMed: PMC4947259
DOI: 10.1186/s12870-016-0844-y
PMID: 27422157
قاعدة البيانات: MEDLINE
الوصف
تدمد:1471-2229
DOI:10.1186/s12870-016-0844-y